133 products were found matching "K05037"!
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Paroxetine (maleate) (CRM)
Item number: Cay40969-1
Paroxetine (maleate) (CRM) (Cay-40969) is a certified reference material categorized as an antidepressant. Paroxetine decreases immobility time in the forced swim test in mice. Formulations containing paroxetine have been used in the treatment of depression, obsessive-compulsive disorder (OCD), panic disorder,...
| Keywords: | (3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)-piperidine, 2Z-butenedioate |
| Application: | Certified reference material, antidepressant |
| CAS | 64006-44-6 |
| MW: | 445.4 D |
48.00€
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Mesembrine
Item number: Cay21100-5
Mesembrine is an alkaloid that has been found in S. tortuosum and has serotonin (5-HT) reuptake inhibitory activity. It selectively binds to the 5-HT transporter (SERT, IC50 = 4.3 µg/ml) over a variety of receptors (IC50s = 148->750 µg/ml). Mesembrine inhibits the reuptake of 5-HT in vitro (Ki = 1.4 nM). It has...
| Keywords: | (-)-Mesembrine, Mesembranone, (3aS,7aS)-3a-(3,4-dimethoxyphenyl)octahydro-1-methyl-6H-indol-6-one |
| Application: | Bioactive alkaloid, 5-HT reuptake inhibitor |
| CAS | 24880-43-1 |
| MW: | 289.4 D |
From 208.00€
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N-Desmethyl Clomipramine hydrochloride
Item number: TGM-T12147-10mg
Description: N-Desmethyl Clomipramine hydrochloride is a primary plasma N-desmethyl Clomipramine metabolite . Target: Others. Smiles: Cl.CNCCCN1c2ccccc2CCc2ccc(Cl)cc12. References: Sioufi A, et al. Simultaneous determination of clomipramine and its N-desmethyl metabolite in human whole blood by capillary gas...
| Keywords: | Desmethylclomipramine hydrochloride |
| Application: | Active clomipramine metabolite |
| CAS | 29854-14-6 |
| MW: | 337.29 D |
From 36.00€
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Paroxetine hydrochloride hemihydrate
Item number: TGM-T1636L-100mg
Description: Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI). Target: 5-HT Receptor. Smiles: FC(C=C1)=CC=C1[C@H](CCNC2)[C@@H]2COC3=CC=C(OCO4)C4=C3.FC(C=C5)=CC=C5[C@H](CCNC6)[C@@H]6COC7=CC=C(OCO8)C8=C7.Cl.O.Cl. References: Drugs and Lactation Database...
| Keywords: | Paroxetine Hydrochloride, Paxil, Seroxat, Paroxetine HCl |
| Application: | 5-hydroxytryptamine reuptake inhibitor |
| CAS | 110429-35-1 |
| MW: | 749.67 D |
From 79.00€
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Citalopram hydrobromide
Item number: TGM-T1483-100mg
Description: Citalopram hydrobromide (XU-62-320) , a selective serotonin reuptake inhibitor (SSRI), selectively inhibits the CNS neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (CNS). Citalopram hydrobromide is the orally bioavailable hydrobromide salt of the...
| Keywords: | XU-62-320, Bonitrile HBr, Lu 10-171, Nitalapram HBr, Lu 10-171 HBr, Citalopram HBr |
| Application: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 59729-32-7 |
| MW: | 405.304 D |
From 40.00€
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Trazodone hydrochloride
Item number: TGM-T1619-100mg
Description: Trazodone hydrochloride (Trazodone HCl) is a serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with...
| Keywords: | KB-831, Trazodone HCl, AF-1161 |
| Application: | Serotonin uptake inhibitor |
| CAS | 25332-39-2 |
| MW: | 408.33 D |
From 31.00€
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Norfluoxetine Hydrochloride
Item number: TGM-T21029-1mg
Description: Norfluoxetine Hydrochloride (Norfluoxetine HCl) is an active metabolite of fluoxetine. Fluoxetine is an antidepressant drug. Target: Others. Smiles: Cl.NCCC(Oc1ccc(cc1)C(F)(F)F)c1ccccc1. References: Shi S, Liu Y, Wu J, Li Z, Zhao Y, Zhong D, Zeng F. Comparative bioavailability and tolerability of a...
| Keywords: | Norfluoxetine HCl |
| Application: | Serotonin uptake inhibitor |
| CAS | 57226-68-3 |
| MW: | 331.76 D |
From 41.00€
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(-)-Mesembrine
Item number: TGM-T28019-10mg
Description: Mesembrine is a serotonin reuptake inhibitor and is also a weak inhibitor of the enzyme phosphodiesterase 4 (PDE4). Target: Others. Smiles: CN1[C@@]2([C@](CC1)(CCC(=O)C2)C3=CC(OC)=C(OC)C=C3)[H]. References: Krstenansky JL. Mesembrine alkaloids: Review of their occurrence, chemistry, and pharmacology. J...
| Keywords: | Mesembrin, Mesembrine, Mesembranone |
| Application: | Bioactive alkaloid, 5-HT reuptake inhibitor |
| CAS | 24880-43-1 |
| MW: | 289.37 D |
From 375.00€
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Alaproclate (hydrochloride)
Item number: TGM-T36521-10mg
Description: Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-alpha-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s = 18, 4, 8, and 12 mg/kg, respectively).1 Alaproclate inhibits NMDA-evoked...
| Application: | Selective serotonin reuptake inhibitor (SSRI) |
| CAS | 60719-83-7 |
| MW: | 292.2 D |
From 164.00€
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meta-Fluoxetine (hydrochloride)
Item number: TGM-T37474-10mg
Description: meta-Fluoxetine (hydrochloride) can be used in related research in the field of life sciences. Its product number is T37474 and CAS number is 79088-29-2. Target: Others. Smiles: Cl.FC(F)(F)C=1C=CC=C(OC(C=2C=CC=CC2)CCNC)C1
| Application: | Impurity, SSRI |
| CAS | 79088-29-2 |
| MW: | 345.79 D |
From 164.00€
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Sertraline Free Base
Item number: TGM-T68683-100mg
Description: Sertraline Free Base is a Selective Serotonin Reuptake Inhibitor (SSRI). It can treat depression, obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social anxiety disorder, and panic disorder. Target: Others. Smiles:...
| Application: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 79617-96-2 |
| MW: | 306.23 D |
From 1,491.00€
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Alaproclate
Item number: TGM-T69013-10mg
Description: Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia. Target: NMDAR. Smiles: O=C(OC(C)(C)CC1=CC=C(Cl)C=C1)C(N)C. References: Campagna J, et al. A small molecule ApoE4-targeted therapeutic candidate that normalizes...
| Application: | Targets solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (SLC6A4, SERT) |
| CAS | 60719-82-6 |
| MW: | 255.74 D |
From 286.00€
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