63 products were found matching "K05032"!
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Nateglinide D5
Item number: TGM-T12178-10mg
Description: Nateglinide D5 is a deuterium labeled Nateglinide. Smiles: [2H]c1c([2H])c([2H])c(C[C@@H](NC(=O)[C@H]2CC[C@@H](CC2)C(C)C)C(O)=O)c([2H])c1[2H]. References: Christopher J. Dunn, et al. Nateglinide. OFILE Drugs 2000 Sep: 60 (3): 6.
| Keywords: | Senaglinide D5, A4166 D5 |
| Application: | GC-MS, LC-MS, internal standard, quantification, hypoglycemic agent |
| CAS | 1227666-13-8 |
| MW: | 322.45 D |
From 694.00€
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Gliclazide
Item number: TGM-T1527-1g
Description: Gliclazide (SE1702), an oral antihyperglycemic agent, belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating beta-cells of the pancreas to release insulin. Target: Potassium Channel. Smiles: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1. References: Mamputu JC, Renier G. J...
| Keywords: | SE1702, S1702 |
| Application: | Targets ATP-binding cassette subfamily C (CFTR/MRP) member 8 (ABCC8, SUR1) |
| CAS | 21187-98-4 |
| MW: | 323.41 D |
From 45.00€
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Glibornuride
Item number: TGM-T15385-100mg
Description: Glibornuride, a blocker of ATP-sensitive K+ channels (pKi: 5.75), inhibits high-affinity [3H]-glibenclamide binding with potencies corresponding to its K+ channel activity. Target: Potassium Channel. Smiles: [H][C@@]12CC[C@@](C)([C@@H](O)[C@H]1NC(=O)NS(=O)(=O)c1ccc(C)cc1)C2(C)C. References: Löffler C,...
| Application: | Targets ATP-binding cassette subfamily C (CFTR/MRP) member 8 (ABCC8, SUR1) |
| CAS | 26944-48-9 |
| MW: | 366.48 D |
From 67.00€
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Glisoxepide
Item number: TGM-T15386-100mg
Description: Glisoxepide is a sulphonamide derivative and is an orally available nonselective K(ATP) channel blocker. It has antihyperglycemic activity and cardiovascular regulation effect. Target: Others. Smiles: S(NC(NN1CCCCCC1)=O)(=O)(=O)C2=CC=C(CCNC(=O)C3=NOC(C)=C3)C=C2. References: Sato T, et al. Bepridil, an...
| Application: | Targets ATP-binding cassette subfamily C (CFTR/MRP) member 8 (ABCC8, SUR1) |
| CAS | 25046-79-1 |
| MW: | 449.52 D |
From 1,520.00€
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Glipizide
Item number: TGM-T1603-1g
Description: Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity. Target: PPAR, ABC, Potassium Channel. Smiles: S(NC(NC1CCCCC1)=O)(=O)(=O)C2=CC=C(CCNC(=O)C=3C=NC(C)=CN3)C=C2. References: Gribble FM, Ashcroft FM. Metabolism. 2000 Oct,49(10 Suppl 2):3-6.
| Keywords: | K 4024, CP 28720 |
| Application: | Targets ATP-binding cassette subfamily C (CFTR/MRP) member 8 (ABCC8, SUR1) |
| CAS | 29094-61-9 |
| MW: | 445.54 D |
From 42.00€
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rac-trans-4-hydroxy Glyburide
Item number: TGM-T35635-1mg
Description: rac-trans-4-hydroxy Glyburide, an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide, is formed by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9. It inhibits glyburide binding to rat brain synaptosomes at high and low affinity sites of SUR1/Kir6.2 with IC50 values of 0.95 and...
| Application: | Glyburide active metabolite |
| CAS | 23155-00-2 |
| MW: | 510 D |
287.00€
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Gliclazide-d4
Item number: TGM-T71981-1mg
Description: Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic beta-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic beta-cell over cardiac and arterial smooth muscle...
| Application: | GC-MS, LC-MS internal standard, quantification, antidiabetic |
| CAS | 1185039-30-8 |
| MW: | 327.44 D |
From 220.00€
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Glibenclamide potassium
Item number: TGM-T72272-10g
Description: Glibenclamide potassium, also known as Glyburide potassium, is a potassium salt form of Glibenclamide. It is available in both anhydrous and hydrate versions, exhibiting greater solubility than the pure Glibenclamide [1]. Target: Others. Smiles:...
| Keywords: | Glyburide potassium |
| Application: | Antidiabetic, K+ channel inhibitor |
| CAS | 52169-36-5 |
| MW: | 532.09 D |
From 239.00€
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Nicorandil-d4
Item number: TGM-T71402-10mg
Description: Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2...
| Application: | GC-MS, LC-MS internal standard, quantification, vasodilator |
| CAS | 1132681-23-2 |
| MW: | 215.2 D |
From 154.00€
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Mitiglinide Calcium
Item number: TGM-T6587-100mg
Description: Mitiglinide Calcium (KAD-1229) is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. Target: Potassium Channel, ATPase. Smiles: [CaH2].OC(=O)[C@H](CC(=O)N1C[C@H]2CCCC[C@H]2C1)Cc1ccccc1. References: Shigeto M,et al.J Pharmacol...
| Keywords: | S21403, KAD-1229 |
| Application: | SUR1/Kir6.2 inhibitor |
| CAS | 145525-41-3 |
| MW: | 668.88 D |
From 31.00€
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Anti-ABCC8
Item number: CSB-PA22439A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: ABCC8. Antigen Species: Human
| Keywords: | Anti-ABCC8, Anti-HRINS, Anti-Sulfonylurea receptor 1, Anti-ATP-binding cassette sub-family C member 8, ABC36 antibody,... |
| Application: | ELISA, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Anti-ABCC8
Item number: CSB-PA590986.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ABCC8. Antigen Species: Human
| Keywords: | Anti-ABCC8, Anti-HRINS, Anti-Sulfonylurea receptor 1, Anti-ATP-binding cassette sub-family C member 8, ABC36 antibody,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, rat |
From 167.00€
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