19 products were found matching "K04961"!

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RYR1. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RYR1. Antigen Species: Human

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-534. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MGDAEGEDEV QFLRTDDEVV LQCSATVLKE QLKLCLAAEG FGNRLCFLEP TSNAQNVPPD LAICCFVLEQ SLSVRALQEM LANTVEAGVE SSQGGGHRTL LYGHAILLRH AHSRMYLSCL TTSRSMTDKL AFDVGLQEDA...

Suramin is a polysulfonated naphthylurea with antiviral, antiparasitic, and anticancer activities. It is negatively charged at physiological pH and therefore binds to various intracellular targets including, but not limited to, ryanodine receptor 1 (IC50 = 4.9 µM), G protein-coupled receptors, P2 purinergic...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse RYR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse RYR1. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RYR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RYR1. Next,...

Dantrolene is an inhibitor of calcium release from the sarcoplasmic reticulum (IC50 = 0.3 µM). It binds to sarcoplasmic reticulum vesicles isolated from normal and malignant hyperthermia-susceptible (MHS) pigs with Kd values of 0.3 and 0.09 µM, respectively. Dantrolene reduces spontaneous calcium wave frequency and...

S107 is a stabilizer of the protein-protein interaction between ryanodine receptor 1 (RyR1) and FK-506 binding protein 1A (FKBP12). It stabilizes sarcoplasmic reticulum RyR1 channels by decreasing the dissociation of FKBP12 in isolated mouse muscle fibers. S107 (50 and 100 µM) also reduces neurite growth and length...

Dantrolene-d4 is intended for use as an internal standard for the quantification of dantrolene (Cay-14326) by GC- or LC-MS. Dantrolene is an inhibitor of calcium release from the sarcoplasmic reticulum (IC50 = 0.3 µM). It binds to sarcoplasmic reticulum vesicles isolated from normal and malignant...

Protein function: Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules (PubMed:11741831, PubMed:16163667). Repeated very high-level exercise increases the open...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....