85 products were found matching "K04850"!
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Darodipine
Item number: Cay41667-10
Darodipine is a calcium channel inhibitor. It selectively inhibits calcium-induced contractions of isolated rabbit aorta (pD2 = 8.8) over norepinephrine-, serotonin-, or angiotensin II-induced contractions at 10 µM. In vivo, continuous infusion of darodipine (2 µg/kg per minute) increases cerebral tissue oxygenation...
| Keywords: | PY 108-068, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, 3,5-diethyl ester |
| Application: | Calcium channel inhibitor |
| CAS | 72803-02-2 |
| MW: | 371.4 D |
From 75.00€
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Nifedipine-d6
Item number: TGM-T12222-10mg
Description: Nifedipine D6 is deuterium labeled nifedipine which is a potent blocker of calcium channel. Smiles: [2H]C([2H])([2H])OC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC([2H])([2H])[2H]. References: Patel DP, et al. Highly sensitive and rapid ultra-performance liquid chromatography-tandem mass...
| Keywords: | BAY-a-1040 D6, Nifedipine D6 |
| Application: | Dihydropyridine calcium channel blocker, GC-MS, LC-MS, internal standard |
| CAS | 1188266-14-9 |
| MW: | 352.37 D |
From 178.00€
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Carboxyamidotriazole
Item number: TGM-T14872-10mg
Description: Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and antiangiogenic effects. Target: Calcium Channel. Smiles: NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N. References:...
| Keywords: | L-651582, CAI |
| Application: | Non-selective calcium channel blocker |
| CAS | 99519-84-3 |
| MW: | 424.67 D |
From 264.00€
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Nemadipine-A
Item number: TGM-T35729-10mg
Description: Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel alpha1-subunit in the C. elegans genome. It also inhibits L-type calcium channels in chick...
| Application: | Cell-permeable L-type calcium channel protein inhibitor |
| CAS | 54280-71-6 |
| MW: | 419.34 D |
From 170.00€
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Bepridil hydrochloride
Item number: TGM-T5391-100mg
Description: Bepridil hydrochloride (CERM 1978) is a calcium channel blocker that also inhibits Na+/Ca2+ exchange (NCX), sodium channels, and cardiac sarcolemmal KATP channels. Target: Calcium Channel. Smiles: Cl.CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1. References: Flaim SF, et al. Effects of bepridil hydrochloride...
| Keywords: | CERM 1978 |
| Application: | Calcium channel blocker |
| CAS | 68099-86-5 |
| MW: | 403 D |
From 42.00€
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CACNA1C Protein, Guinea Pig, Recombinant (His)
Item number: TGM-TMPH-00780-100ug
Description: Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required...
| Keywords: | Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, CCHL1A1, Voltage-gated calcium channel subunit... |
| MW: | 22.3 kD |
From 1,709.00€
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Amlodipine-d4 Maleate (Racemic)
Item number: TGM-TMIH-0087-1mg
Description: Amlodipine-d4 Maleate (Racemic) is a deuterated compound of Amlodipine Maleate (Racemic). Amlodipine Maleate (Racemic) has a CAS number of 88150-47-4. Amlodipine maleate is an orally active dihydropyridine calcium channel blocker that inhibits calcium inward flow by blocking voltage-dependent L-type...
| Application: | Internal standard, GC-MS, LC-MS |
| CAS | 1185246-15-4 |
| MW: | 528.97 D |
128.00€
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Nimodipine-d7
Item number: TGM-TMIJ-0095-1mg
Description: Nimodipine-d7 is a deuterated compound of Nimodipine. Nimodipine has a CAS number of 66085-59-4. Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells. Smiles:...
| Application: | GC-MS, LC-MS, internal standard, Ca2+ channel antagonist |
| CAS | 1246815-36-0 |
| MW: | 425.48 D |
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Felodipine-d5
Item number: TGM-TMIJ-0140-1mg
Description: Felodipine-d5 is a deuterated compound of Felodipine. Felodipine has a CAS number of 72509-76-3. Felodipine is a longlasting 1, 4-dihydropyridine calcium channel repressor. Smiles: C1C(C2C(C(=O)OC)=C(C)NC(C)=C2C(=O)OC([2H])([2H])C([2H])([2H])[2H])=C(Cl)C(Cl)=CC=1
| Application: | GC-MS, LC-MS, internal standard, quantification, L-type calcium channel inhibitor |
| CAS | 1242281-38-4 |
| MW: | 389.29 D |
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(R)-(+)-Bay-K-8644
Item number: TGM-TQ0145-1mg
Description: (R)-(+)-Bay-K-8644 is a Ca2+ channel and dihydropyridine agonist that inhibits Ba2+ currents (IBa), induces central respiratory depression in cats, and inhibits platelet activation through competitive antagonism of thromboxane A2-prostaglandin H2 receptors. Target: Calcium Channel, PPAR. Smiles:...
| Keywords: | (R)-(+)-Bay K 8644 |
| Application: | L-type channel blocker |
| CAS | 98791-67-4 |
| MW: | 356.3 D |
From 52.00€
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Manidipine
Item number: TGM-T6577-100mg
Description: Manidipine (Iperten), a calcium channel blocker, which is dihydropyridine type. It is utilized. Target: Calcium Channel. Smiles: C(OCCN1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1)(=O)C=4C(C(C(OC)=O)=C(C)NC4C)C5=CC(N(=O)=O)=CC=C5. References: Roth M, et al. Proc Natl Acad Sci U S A, 1992, 89(9), 4071-4075.
| Keywords: | Franidipine, Iperten, Artedil |
| Application: | L-type / T-type calcium channel blocker |
| CAS | 89226-50-6 |
| MW: | 610.7 D |
From 40.00€
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Voltage-dependent L-type calcium channel subunit alpha-1C...
Item number: CSB-CF004399GU.100
Organism: Cavia porcellus (Guinea pig). Source: in vitro E.coli expression system. Expression Region: 1-169aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: FQEQGEQEYK NCELDKNQRQ CVEYALKARP LRRYIPISIT FFRLFRVMRL VKLLSRGEGI RTLLWTFIKS FQALPYVALL IVMLFFIYAV IGMQVFGKIA LNDTTEINRN...
| Keywords: | CACH2, CACNA1C, Voltage-gated calcium channel subunit alpha Cav1.2, Voltage-dependent L-type calcium channel subunit... |
| Application: | Activity not tested |
| Expressed in: | E.coli in vitro |
| Origin: | Cavia porcellus (Guinea pig) |
| MW: | 22.3 kD |
From 799.00€
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