- Search results for K04833
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47 products were found matching "K04833"!
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Item number: CSB-BP020834HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-128aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MEQTVLVPPG PDSFNFFTRE SLAAIERRIA EEKAKNPKPD KKDDDENGPK PNSDLEAGKN LPFIYGDIPP EMVSEPLEDL DPYYINKKTF IVLNKGKAIF RFSATSALYI...
Keywords: | NAC1, SCN1A, Sodium channel protein type I subunit alpha, Sodium channel protein type 1 subunit alpha, Sodium channel... |
Application: | Activity not tested |
Expressed in: | Insect cells |
Origin: | human |
MW: | 18.3 kD |
From 474.00€
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NEW
Item number: CSB-EP020834HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-128aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MEQTVLVPPG PDSFNFFTRE SLAAIERRIA EEKAKNPKPD KKDDDENGPK PNSDLEAGKN LPFIYGDIPP EMVSEPLEDL DPYYINKKTF IVLNKGKAIF RFSATSALYI LTPFNPLRKI AIKILVHS. Purity:...
Keywords: | NAC1, SCN1A, Sodium channel protein type I subunit alpha, Sodium channel protein type 1 subunit alpha, Sodium channel... |
Application: | Activity not tested |
Expressed in: | E.coli |
Origin: | human |
MW: | 18.5 kD |
From 283.00€
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Item number: Cay38904-10
Levobupivacaine-d9 is intended for use as an internal standard for the quantification of levobupivacaine (Cay-31596) by GC- or LC-MS. Levobupivacaine is a sodium channel blocker and local anesthetic, as well as the levorotary stereoisomer of bupivacaine (Cay-16618). It inhibits cardiac sodium channel currents (INa)...
Keywords: | (S)-(-)-Bupivacaine-d9, 1-butyl-d9-N-(2,6-dimethylphenyl)-(2S)-2-piperidinecarboxamide, monohydrochloride |
Application: | GC-MS, LC-MS internal standard, quantification, sodium channel blocker, local anesthetic |
MW: | 333.9 D |
From 82.00€
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Item number: Cay40428-10
AA43279 is an activator of voltage-gated sodium channel 1.1 (Nav1.1, EC50 = 9.5 µM in a patch-clamp assay using HEK293 cells expressing the human channel). It is selective for Nav1.1 over Nav1.4 and Nav1.7 at 30 µM but also activates Nav1.2, Nav1.5, and Nav1.6 (EC50s = 22.8, 14.4, and 11.6 µM, respectively). AA43279...
Keywords: | 3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide |
Application: | Nav1.1 activator |
CAS | 354812-16-1 |
MW: | 248.3 D |
From 66.00€
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Item number: Cay35008-10
Eslicarbazepine is a voltage-gated sodium channel (Nav) inhibitor and an active metabolite of the prodrug eslicarbazepine acetate (Cay-23656). It enhances slow activation of voltage-gated sodium channels, reducing channel availability. Eslicarbazepine is protective against seizures induced by maximal electroshock...
Keywords: | (S)-Licarbazepine, BIA 2-194, CGP 13751, (10S)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide |
Application: | Eslicarbazepine acetate active metabolite, voltage-gated sodium channel inhibitor |
CAS | 104746-04-5 |
MW: | 254.3 D |
From 48.00€
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Item number: Cay28884-2.5
Quinidine-d3 is intended for use as an internal standard for the quantification of quinidine (Cay-20356) by GC- or LC-MS. Quinidine is a stereoisomer of the antimalarial agent quinine (Cay-23958) and a class Ia antiarrhythmic agent. Quinidine blocks the voltage-gated sodium (Nav) channel Nav1.5 in a use-dependent...
Keywords: | (+)-Quinidine-d3, beta-Quinidine-d3, 6'-(methoxy-d3)-cinchonan-9S-ol |
Application: | GC-MS, LC-MS, internal standard, quantification, sodium channel blocker |
CAS | 1267657-68-0 |
MW: | 327.4 D |
448.00€
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Item number: Cay17340-10
Oxcarbazepine is a prodrug form of the antiepileptic compound 10,11-dihydro-10-hydroxy carbamazepine (Cay-18467). It inhibits high-frequency repetitive firing of rat spinal cord neurons when used at a concentration of 1 µM. Oxcarbazepine protects against electroshock-induced tonic hindlimb extension (ED50 = 10-20...
Keywords: | GP47680, 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide |
Application: | 10-hydroxycarbazepine prodrug, voltage-gated sodium channel blocker |
CAS | 28721-07-5 |
MW: | 252.3 D |
From 43.00€
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Item number: Cay24183-100
Zonisamide is a broad-spectrum sulfonamide antiepileptic agent. It selectively blocks the repeated firing of sodium channels (IC50 = 2 µg/ml) at low concentrations in mouse embryo spinal cord neurons, and it blocks spontaneous channel firing at concentrations above 10 µg/ml. In rat cerebral cortex neurons,...
Keywords: | CI-912, PD 110843, 1,2-benzisoxazole-3-methanesulfonamide |
Application: | Antiepileptic |
CAS | 68291-97-4 |
MW: | 212.2 D |
From 77.00€
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Item number: Cay18467-10
10,11-dihydro-10-hydroxy Carbamazepine is an antiepileptic agent and active metabolite of the prodrug oxcarbazepine (Cay-17340). It is a racemic mixture of (R)- and (S)-10,11-dihydro-10-hydroxy carbamazepine. (S)-10,11-dihydro-10-hydroxy Carbamazepine protects against seizures induced by maximal electroshock (MES)...
Keywords: | 10,11-hydroxy-10,11 Dihydrocarbamezer, BIA 2-005, GP 47779, Licarbazepine,... |
Application: | Anticonvulsant, voltage-gated sodium channel SCN1A, SCN2A, SCN3A, SCN4A, SCN5A, SCN8A, SCN9A blocker |
CAS | 29331-92-8 |
MW: | 254.3 D |
From 68.00€
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Item number: Cay18870-10
Lennox-Gastaut syndrome (LGS) is a severe pediatric epilepsy syndrome characterized by multiple seizure types. Rufinamide is an anticonvulsant. It inhibits the activation of voltage-gated sodium channel 1.1 (Nav1.1) when used at a concentration of 100 µM. Rufinamide inhibits Nav1.1, but not Nav1.2, Nav1.3, and...
Keywords: | CGP 33101, RUF 331, 1-[(2,6-difluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide |
Application: | Antiepileptic |
CAS | 106308-44-5 |
MW: | 238.2 D |
From 43.00€
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Item number: Cay23889-100
Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker, in vivo. It induces less tissue damage compared with two other phenytoin prodrugs in rats following subcutaneous and intramuscular administration. Fosphenytoin has anticonvulsant activity in a mouse...
Keywords: | ACC-9653, Cl-982, 5,5-diphenyl-3-[(phosphonooxy)methyl]-2,4-imidazolidinedione, disodium salt |
Application: | Voltage-gated sodium channel blocker prodrug |
CAS | 92134-98-0 |
MW: | 406.2 D |
From 60.00€
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Item number: Cay33486-1
Carbamazepine-d10 is intended for use as an internal standard for the quantification of carbamazepine by GC- or LC-MS. Carbamazepine is an anticonvulsant. It reduces the occurrence of seizures in mouse models of tonic-clonic, or maximal electroshock-induced, seizures (ED50s = 15.46 and ~13 mg/kg, respectively)....
Keywords: | Carbazepine-d10, 5H-dibenz[b,f]azepine-1,2,3,4,6,7,8,9,10,11-d10-5-carboxamide |
Application: | Internal standard, GC-MS, LC-MS, Quantification, Anticonvulsant |
CAS | 132183-78-9 |
MW: | 246.3 D |
From 147.00€
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