37 products were found matching "K04813"!
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NS9283
Item number: TGM-T28199-100mg
Description: NS9283, a positive allosteric modulator selective for the alpha4beta2 form, reduces ethanol consumption. Target: AChR. Smiles: C(#N)C=1C=C(C2=NC(=NO2)C=3C=CC=NC3)C=CC1. References: Maurer JJ, et al. Attenuation of nicotine taking and seeking in rats by the stoichiometry-selective alpha4beta2 nicotinic...
| Keywords: | NS 9283, NS-9283 |
| Application: | nAChR (alpha4beta2) positive allosteric modulator |
| CAS | 913830-15-6 |
| MW: | 248.24 D |
From 40.00€
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TMB 8 (hydrochloride)
Item number: TGM-T36554-10mg
Description: TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and alpha3beta4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat...
| Application: | Nicotinic acetylcholine receptor non-competitive antagonist |
| CAS | 53464-72-5 |
| MW: | 431.99 D |
From 68.00€
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CHRNB2 Protein, Human, Recombinant (His & V5)
Item number: TGM-TMPH-01763-100ug
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. CHRNB2 Protein, Human, Recombinant (His & V5) is expressed in E. coli expression system...
| Keywords: | CHRNB2, Neuronal acetylcholine receptor subunit beta-2 |
| MW: | 31.9 kD |
From 284.00€
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Acetamiprid
Item number: TGM-T14094-100mg
Description: Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist. Acetamiprid is a neonicotinoid insecticide used worldwide. It is shown to be associated with neuromuscular and reproductive disorders. Target: AChR. Smiles: CN(Cc1ccc(Cl)nc1)C(\C)=N\C#N. References: Terayama H, et al. Effect of...
| Application: | Neonicotinoid insecticide, nAchR agonist |
| CAS | 135410-20-7 |
| MW: | 222.67 D |
From 43.00€
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Neuronal acetylcholine receptor subunit beta-2 (CHRNB2),...
Item number: CSB-EP005396HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 26-233aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-V5-tagged. Target Protein Sequence: TDTEERLVEH LLDPSRYNKL IRPATNGSEL VTVQLMVSLA QLISVHEREQ IMTTNVWLTQ EWEDYRLTWK PEEFDNMKKV RLPSKHIWLP DVVLYNNADG MYEVSFYSNA VVSYDGSIFW LPPAIYKSAC...
| Keywords: | CHRNB2, Neuronal acetylcholine receptor subunit beta-2, Recombinant Human Neuronal acetylcholine receptor subunit beta-2... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 31.9 kD |
From 292.00€
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Varenicline (tartrate)
Item number: Cay15030-5
Varenicline is a full agonist of alpha7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs, EC50 = 18 µM) and a partial agonist of alpha4beta2 subunit-containing nAChRs (EC50 = 2.3 µM). Formulations containing varenicline have been used as aids in smoking cessation.Formal Name:...
| Keywords: | CP 526,555-18, 7,8,9,10-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine-(2R,3R)-dihydroxybutanedioate |
| Application: | alpha4beta2 neuronal nicotinic acetylcholine receptor agonist |
| CAS | 375815-87-5 |
| MW: | 361.4 D |
From 145.00€
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TMB 8 (hydrochloride)
Item number: Cay23928-10
TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and alpha3beta4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat brain...
| Keywords: | 3,4,5-trimethoxy-benzoic acid, 8-(diethylamino)octyl ester, monohydrochloride |
| Application: | Nicotinic acetylcholine receptor non-competitive antagonist |
| CAS | 53464-72-5 |
| MW: | 432 D |
From 39.00€
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Varenicline-d4
Item number: Cay26102-500
Varenicline-d4 is intended for use as an internal standard for the quantification of varenicline (Cay-15030) by GC- or LC-MS. Varenicline is a full agonist of alpha7 subunit-containing neuronal nicotinic acetylcholine receptors (nAChRs, EC50 = 18 µM) and a partial agonist of alpha4beta2 subunit-containing nAChRs...
| Keywords: | 7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline-7,7,9,9-d4 |
| Application: | GC-MS, LC-MS, Internal standard, Alpha4beta2 neuronal nicotinic acetylcholine receptor agonist |
| CAS | 2183239-01-0 |
| MW: | 215.3 D |
From 128.00€
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Anti-CHRNB2, Internal
Item number: ARG64701.100
Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions. [The UniProt Consortium]
| Keywords: | Anti-CHRNB2, Anti-Neuronal acetylcholine receptor subunit beta-2 |
| Application: | ELISA, WB |
| Host: | Goat |
| Species reactivity: | human |
822.00€
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Anti-CHRNB2
Item number: NSJ-R35399-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cholinergic receptor nicotinic beta 2 Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an...
| Keywords: | Anti-CHRNB2, Anti-Neuronal acetylcholine receptor subunit beta-2, CHRNB2 Antibody |
| Application: | WB, IHC (paraffin), ELISA (peptide) |
| Host: | Goat |
| Species reactivity: | human |
790.00€
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Varenicline Tartrate
Item number: LKT-V0369.10
alpha7 and beta4 nAChR agonist, alpha4beta2 and alpha6beta2 nAChR partial agonist.
| Application: | alpha-4 beta-2 nicotinic receptor partial agonist |
| CAS | 375815-87-5 |
| MW: | 361.35 D |
From 117.00€
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Morantel (tartrate)
Item number: Cay22902-250
Morantel is a positive allosteric modulator of neuronal nicotinic acetylcholine receptors (nAChRs). It enhances channel gating of the alpha3beta2 nAChR subtype by binding to non-canonical sites. Formulations containing morantel are used to treat nematode infections in livestock.Formal Name:...
| Keywords: | CP 12,009-18, UK 2964-18, 1,4,5,6-tetrahydro-1-methyl-2-[(2E)-2-(3-methyl-2-thienyl)ethenyl]-pyrimidine,... |
| Application: | Anthelmintic, nicotinic cholinergic receptor alpha3beta2 enhancer |
| CAS | 26155-31-7 |
| MW: | 370.4 D |
From 52.00€
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