35 products were found matching "K04805"!
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(±)-Nicotine
Item number: Cay16535-100
(±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs, Kis = 481 and 11.1 nM for alpha3beta4 and alpha4beta2 subtypes, respectively) and possesses addictive and teratogenic properties. (-)-(S)-Nicotine is...
| Keywords: | DL-Nicotine, 3-(1-methyl-2-pyrrolidinyl)-pyridine |
| Application: | nAChR agonist |
| CAS | 22083-74-5 |
| MW: | 162.2 D |
From 149.00€
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NS3861
Item number: TGM-T9542-100mg
Description: NS3861 is an agonist of nicotinic acetylcholine receptors (nAChRs) that binds with high affinity to heteromeric alpha3beta4 and alpha4beta2 nAChRs, displaying beta-subunit preference and no activation at alpha4-containing receptors. The maximal efficacy of NS3861 depends on the ligand-binding domain,...
| Application: | Neuronal nAChR agonist |
| CAS | 216853-59-7 |
| MW: | 284.22 D |
From 41.00€
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CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO)
Item number: TGM-TMPH-01762-100ug
Description: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO...
| Keywords: | Neuronal acetylcholine receptor subunit alpha-3, NACHRA3, CHRNA3 |
| MW: | 44.6 kD |
From 201.00€
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Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3),...
Item number: CSB-BP005389HU1.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 32-240aa. Protein Length: Extracellular Domain. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: SEAEHRLFER LFEDYNEIIR PVANVSDPVI IHFEVSMSQL VKVDEVNQIM ETNLWLKQIW NDYKLKWNPS DYGGAEFMRV PAQKIWKPDI VLYNNAVGDF QVDDKTKALL KYTGEVTWIP...
| Keywords: | CHRNA3, NACHRA3, Neuronal acetylcholine receptor subunit alpha-3, Recombinant Human Neuronal acetylcholine receptor... |
| Application: | Activity not tested |
| Expressed in: | Insect cells |
| Origin: | human |
| MW: | 26.6 kD |
From 489.00€
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Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3),...
Item number: CSB-EP005389HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 32-240aa. Protein Length: Extracellular Domain. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: SEAEHRLFER LFEDYNEIIR PVANVSDPVI IHFEVSMSQL VKVDEVNQIM ETNLWLKQIW NDYKLKWNPS DYGGAEFMRV PAQKIWKPDI VLYNNAVGDF...
| Keywords: | CHRNA3, NACHRA3, Neuronal acetylcholine receptor subunit alpha-3, Recombinant Human Neuronal acetylcholine receptor... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 44.6 kD |
From 219.00€
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Neuronal acetylcholine receptor subunit alpha-3 (CHRNA3),...
Item number: CSB-YP005389HU1.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 32-240aa. Protein Length: Extracellular Domain. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: SEAEHRLFER LFEDYNEIIR PVANVSDPVI IHFEVSMSQL VKVDEVNQIM ETNLWLKQIW NDYKLKWNPS DYGGAEFMRV PAQKIWKPDI VLYNNAVGDF QVDDKTKALL KYTGEVTWIP PAIFKSSCKI...
| Keywords: | CHRNA3, NACHRA3, Neuronal acetylcholine receptor subunit alpha-3, Recombinant Human Neuronal acetylcholine receptor... |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | human |
| MW: | 26.0 kD |
From 347.00€
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Anti-CHRNA3
Item number: CSB-PA000802.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-CHRNA3, Anti-NACHRA3, Anti-Neuronal acetylcholine receptor subunit alpha-3, ACHA3_HUMAN antibody, AChR antibody,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
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Anti-CHRNA3
Item number: CSB-PA085715.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA3. Antigen Species: Human
| Keywords: | Anti-CHRNA3, Anti-NACHRA3, Anti-Neuronal acetylcholine receptor subunit alpha-3, ACHA3_HUMAN antibody, AChR antibody,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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NS 3861
Item number: Cay37406-10
NS 3861 is a neuronal nicotinic acetylcholine receptor (nAChR) agonist. It induces inward currents in patch-clamp assays using X. laevis oocytes expressing recombinant human alpha3beta2- or alpha3beta4 subunit-containing nAChR receptors (EC50s = 1.6 and 1 µM, respectively). In vivo, NS 3861 (0.1 mg/kg) increases the...
| Keywords: | 3-(3-bromo-2-thienyl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene |
| Application: | Neuronal nAChR agonist |
| CAS | 216853-59-7 |
| MW: | 284.2 D |
From 136.00€
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Mecamylamine (hydrochloride)
Item number: Cay14602-10
Mecamylamine is a noncompetitive nicotinic acetylcholine receptor antagonist with preferential activity at the alpha3beta4 subtype (IC50 = 90-640 nM) compared to alpha4beta2, alpha3beta2, and alpha7 subtypes (IC50 range from 1-7 µM). Mecamylamine is widely used as a broad-spectrum antagonist of neuronal nicotinic...
| Keywords: | Inversine, N,2,3,3-tetramethyl-bicyclo[2.2.1]heptan-2-amine, monohydrochloride |
| Application: | Nicotinic acetylcholine receptor antagonist |
| CAS | 826-39-1 |
| MW: | 203.8 D |
From 61.00€
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Morantel (tartrate)
Item number: Cay22902-100
Morantel is a positive allosteric modulator of neuronal nicotinic acetylcholine receptors (nAChRs). It enhances channel gating of the alpha3beta2 nAChR subtype by binding to non-canonical sites. Formulations containing morantel are used to treat nematode infections in livestock.Formal Name:...
| Keywords: | CP 12,009-18, UK 2964-18, 1,4,5,6-tetrahydro-1-methyl-2-[(2E)-2-(3-methyl-2-thienyl)ethenyl]-pyrimidine,... |
| Application: | Anthelmintic, nicotinic cholinergic receptor alpha3beta2 enhancer |
| CAS | 26155-31-7 |
| MW: | 370.4 D |
From 52.00€
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Chlorisondamine (iodide)
Item number: Cay20119-25
Chlorisondamine is an antagonist of nicotinic acetylcholine receptors (nAChRs, IC50 = 1.8 µM in rat striatal synaptosomes) and a ganglion blocker. It decreases dopamine release induced by nicotine (Cay-16535, Cay-20887) in a dose-dependent manner in rat striatal synaptosomes at concentrations ranging from 0-100 µM....
| Keywords: | 4,5,6,7-tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-1H-isoindolium, diiodide |
| Application: | Nicotinic acetylcholine receptor antagonist |
| CAS | 96750-66-2 |
| MW: | 611.9 D |
From 52.00€
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