- Search results for K04675
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84 products were found matching "K04675"!
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Item number: CSB-PA281732.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ACVR1. Antigen Species: Human
Keywords: | Anti-SKR1, Anti-ALK-2, Anti-TSR-I, Anti-ACVR1, Anti-ACTR-I, Anti-ACVRLK2, EC=2.7.11.30, Anti-Activin receptor type I,... |
Application: | ELISA, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 163.00€
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Item number: Cay16679-10
Bone morphogenetic proteins (BMP) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation. DMH1 is an analog of the non-selective BMP receptor inhibitor dorsomorphin (Cay-11967) that potently inhibits the kinase activity of activin receptor-like...
Keywords: | BMP Inhibitor II, DorsoMorphin Homolog 1, VU036482, 4-[6-[4-(1-methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
Application: | ALK2 inhibitor |
CAS | 1206711-16-1 |
MW: | 380.4 D |
From 52.00€
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Item number: ELK-ELK4461.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ACVR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ACVR1. Next,...
Keywords: | SKR1, TSR-I, ACVR1, ALK-2, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | ELISA |
Species reactivity: | human |
From 365.00€
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Item number: Cay19396-1
LDN-193189 inhibits SMAD1/5/8 phosphorylation by the bone morphogenetic protein (BMP) type I receptors, which are known as activin receptor-like kinases (ALKs), with an IC50 value of 4.9 nM. In in vitro kinase assays, it shows specificity for ALK1, 2, 3, and 6 (IC50s = 0.8, 0.8, 5.3, and 16.7 nM, respectively) over...
Keywords: | DM-3189, 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline, dihydrochloride |
Application: | ALK1 / ALK2 / ALK3 / ALK6 inhibitor |
CAS | 1435934-00-1 |
MW: | 479.4 D |
From 32.00€
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Item number: BPS-101935
Recombinant human ALK2 (PF197_198L) (activin receptor-like kinase-2), encompassing amino acids 147-end with a PF197_198L mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
Keywords: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Origin: | human |
MW: | 67 kD |
914.00€
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Item number: BPS-101936
Recombinant human ALK2 (Q207D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
Keywords: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Origin: | human |
MW: | 67 kD |
914.00€
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Item number: BPS-101937
Recombinant human ALK2 (Q207E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active
Keywords: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Origin: | human |
MW: | 67 kD |
914.00€
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Item number: BPS-101931
Recombinant human ALK2 (G328E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
Keywords: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Insect cells |
Origin: | human |
MW: | 67 kD |
914.00€
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Item number: BPS-101932
Recombinant human ALK2 (G328V) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328V mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
Keywords: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Insect cells |
Origin: | human |
MW: | 67 kD |
914.00€
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Item number: BPS-101933
Recombinant human ALK2 (G328W) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328W mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
Keywords: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Insect cells |
Origin: | human |
MW: | 67 kD |
914.00€
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Item number: BPS-101934
Recombinant human ALK2 (G356D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G356D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
Keywords: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Insect cells |
Origin: | human |
MW: | 67 kD |
914.00€
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Item number: Cay11802-10
Normal development and tissue repair are controlled in part by SMADs, a family of intracellular proteins that are activated by signaling via serine/threonine kinase receptors of the TGF-beta superfamily. LDN-193189 inhibits SMAD1/5/8 phosphorylation by the bone morphogenetic protein (BMP) type I receptors, which are...
Keywords: | 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
Application: | BMP type I receptor inhibitor |
CAS | 1062368-24-4 |
MW: | 406.5 D |
From 44.00€
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