35 products were found matching "K04607"!
No results were found for the filter!
VU0422288
Item number: TGM-T29135-100mg
Description: VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobilization assay.VU0422288 can be used to study Rett syndrome (RTT). Target: GluR. Smiles: Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1. References:...
| Keywords: | ML 396, VU 0422288, VU-0422288, ML-396, ML396 |
| Application: | Group III metabotropic glutamate receptor positive allosteric modulator |
| CAS | 1630936-95-6 |
| MW: | 360.19 D |
From 72.00€
*
Lu AF21934
Item number: TGM-T3539-100mg
Description: Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human). Target: GluR. Smiles: NC(=O)[C@@H]1CCCC[C@@H]1C(=O)Nc1ccc(Cl)c(Cl)c1. References: Slawinska A, et al. Anxiolytic- but not antidepressant-like activity of Lu AF21934, a novel, selective...
| Application: | mGluR4 positive allosteric modulator (PAM) |
| CAS | 1445605-23-1 |
| MW: | 315.2 D |
From 35.00€
*
TCN238
Item number: TGM-T7494-100mg
Description: TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 µM). Target: GluR. Smiles: Nc1nccc(\C=C\c2ccccc2)n1. References: Pershina E V , Arkhipov V I . Subacute activation of mGlu4 receptors causes the feedback inhibition of its...
| Keywords: | TCN 238 |
| Application: | Positive allosteric mGluR4 modulator |
| CAS | 125404-04-8 |
| MW: | 197.24 D |
From 31.00€
*
VU0364770
Item number: TGM-T6727-100mg
Description: VU0364770 (VU 0364770)(EC50=1.1 µM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu subtypes. Target: GluR. Smiles: Clc1cccc(NC(=O)c2ccccn2)c1. References: Jones CK, et al. J Pharmacol Exp Ther, 2012, 340(2), 404-421.
| Keywords: | VU 0364770 |
| Application: | mGluR4 postitive allosteric modulator |
| CAS | 61350-00-3 |
| MW: | 232.67 D |
From 31.00€
*
VU 0364439
Item number: TGM-T6160-100mg
Description: VU 0364439 is an mGlu4 positive allosteric modulator (C50: 19.8 nM). Target: GluR. Smiles: Clc1ccccc1NS(=O)(=O)c1ccc(NC(=O)c2ccccn2)cc1Cl. References: Engers DW, et al. Bioorg Med Chem Lett, 2010, 20(17), 5175-5178.
| Application: | Positive allosteric mGluR4 modulator |
| CAS | 1246086-78-1 |
| MW: | 422.29 D |
From 42.00€
*
O-Phospho-L-serine
Item number: TGM-T1324-100mg
Description: O-Phospho-L-serine (Phosphoserine) is the phosphoric acid ester of serine. Target: NMDAR, Amino Acids and Derivatives, Endogenous Metabolite, GluR. Smiles: C([C@@H](C(O)=O)N)OP(=O)(O)O. References: Nakamura T, et al. Biosci Biotechnol Biochem. 2015 Mar 17:1-7.
| Keywords: | Dexfosfoserine, L-SOP, Phosphoserine, L-Serine O-phosphate |
| Application: | mGluR4 / mGluR6 agonist |
| CAS | 407-41-0 |
| MW: | 185.07 D |
From 34.00€
*
Anti-GRM4
Item number: CSB-PA003235.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-GRM4, Anti-mGluR4, Anti-GPRC1D, Anti-Metabotropic glutamate receptor 4, Glutamate receptor metabotropic 4 antibody,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
*
Anti-GRM4
Item number: CSB-PA116412.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRM4. Antigen Species: Human
| Keywords: | Anti-GRM4, Anti-mGluR4, Anti-GPRC1D, Anti-Metabotropic glutamate receptor 4, Glutamate receptor metabotropic 4 antibody,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
*
Anti-GRM4
Item number: CSB-PA693203.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Keywords: | Anti-GRM4, Anti-mGluR4, Anti-GPRC1D, Anti-Metabotropic glutamate receptor 4, Glutamate receptor metabotropic 4 antibody,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
283.00€
*
Anti-GRM4
Item number: CSB-PA923348.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRM4. Antigen Species: Human
| Keywords: | Anti-GRM4, Anti-mGluR4, Anti-GPRC1D, Anti-Metabotropic glutamate receptor 4, Glutamate receptor metabotropic 4 antibody,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
*
VU0361737
Item number: Cay16295-1
Metabotropic glutamate receptors (mGluRs) modulate brain excitability through diverse mechanisms. VU0361737 is a selective positive allosteric modulator (PAM) of mGluR4, displaying EC50 values of 110 and 240 nM for rat and human receptors, respectively. It has weak or no activity at other mGluRs. VU0361737 passes...
| Keywords: | N-(4-chloro-3-methoxyphenyl)-2-pyridinecarboxamide |
| Application: | mGluR4 positive allosteric modulator |
| CAS | 1161205-04-4 |
| MW: | 262.7 D |
From 44.00€
*
O-Phospho-L-Serine
Item number: Cay16151-1
O-Phospho-L-Serine is an agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM). It mimics the phosphatidylserine head group and has been shown to inhibit the proliferation of microglia and to enhance neuronal differentiation of progenitor cells.Formal Name:...
| Keywords: | Dexfosfoserine, L-Serine-O-Phosphate, L-SOP, O-phosphono-L-serine |
| Application: | mGluR4 / mGluR6 agonist |
| CAS | 407-41-0 |
| MW: | 185.1 D |
From 35.00€
*