39 products were found matching "K04583"!

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NNC-0640
NNC-0640

Item number: Cay41234-1

NNC-0640 is a negative allosteric modulator of the glucagon receptor (GCGR, Ki = 39.8 nM).Formal Name: 4-[[(4-cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-yl-benzamide. CAS Number: 307986-98-7. Molecular Formula: C29H31N7O4S. Formula Weight: 573.7. Purity: >98%....
Keywords: 4-[[(4-cyclohexylphenyl)[[[3-(methylsulfonyl)phenyl]amino]carbonyl]amino]methyl]-N-2H-tetrazol-5-yl-benzamide
Application: GCGR negative allosteric modulator
CAS 307986-98-7
MW: 573.7 D
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Glucagon Receptor Antagonist 3
Glucagon Receptor Antagonist 3

Item number: Cay41243-1

Glucagon receptor antagonist 3 is an antagonist of the glucagon receptor.Formal Name: (alphaR,4R)-rel-4-(4-fluoro-2-hydroxyphenyl)-alpha-methyl-2,6-bis(1-methylethyl)-5-propyl-3-pyridinemethanol. CAS Number: 202917-17-7. Molecular Formula: C22H30FNO2. Formula Weight: 359.5. Purity: >95%. Formulation: (Request...
Keywords: (alphaR,4R)-rel-4-(4-fluoro-2-hydroxyphenyl)-alpha-methyl-2,6-bis(1-methylethyl)-5-propyl-3-pyridinemethanol
Application: Glucagon receptor antagonist
CAS 202917-17-7
MW: 359.5 D
From 127.00€ *
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Glucagon receptor (GCGR), partial, human, recombinant
Glucagon receptor (GCGR), partial, human, recombinant

Item number: CSB-BP009316HU1.1

Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA K....
Keywords: GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial
Application: Activity not tested
Expressed in: Insect cells
Origin: human
MW: 16.9 kD
From 474.00€ *
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Glucagon receptor (GCGR), human, recombinant
Glucagon receptor (GCGR), human, recombinant

Item number: CSB-CF009316HU.100

Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 26-477aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW...
Keywords: GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR)
Application: Activity not tested
Expressed in: E.coli in vitro
Origin: human
MW: 54.1 kD
From 914.00€ *
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Glucagon receptor (GCGR), partial, human, recombinant
Glucagon receptor (GCGR), partial, human, recombinant

Item number: CSB-YP009316HU1.1

Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA K. Purity: Greater than 90% as...
Keywords: GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial
Application: Activity not tested
Expressed in: Yeast
Origin: human
MW: 15.1 kD
From 395.00€ *
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Glucagon receptor (Gcgr), partial, mouse, recombinant
Glucagon receptor (Gcgr), partial, mouse, recombinant

Item number: CSB-YP009316MO.1

Organism: Mus musculus (Mouse). Source: Yeast. Expression Region: 27-143aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AQVMDFLFEK WKLYSDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPPNT TANISCPWYL PWYHKVQHRL VFKRCGPDGQ WVRGPRGQPW RNASQCQLDD EEIEVQKGVA KMYSSQQ. Purity: Greater than 90%...
Keywords: GL-R, Gcgr, Glucagon receptor, Recombinant Mouse Glucagon receptor (Gcgr), partial
Application: Activity not tested
Expressed in: Yeast
Origin: mouse
MW: 15.8 kD
From 283.00€ *
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Glucagon receptor (GCGR), partial, human, recombinant
Glucagon receptor (GCGR), partial, human, recombinant

Item number: CSB-EP009316HU1.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA K....
Keywords: GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial
Application: Activity not tested
Expressed in: E.coli
Origin: human
MW: 20.5 kD
From 354.00€ *
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Glucagon receptor (Gcgr), partial, mouse, recombinant
Glucagon receptor (Gcgr), partial, mouse, recombinant

Item number: CSB-EP009316MO.1

Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 27-143aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged. Target Protein Sequence: AQVMDFLFEK WKLYSDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPPNT TANISCPWYL PWYHKVQHRL VFKRCGPDGQ WVRGPRGQPW RNASQCQLDD EEIEVQKGVA KMYSSQQ. Purity: Greater than 90% as...
Keywords: GL-R, Gcgr, Glucagon receptor, Recombinant Mouse Glucagon receptor (Gcgr), partial
Application: Activity not tested
Expressed in: E.coli
Origin: mouse
MW: 40.8 kD
From 283.00€ *
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Glucagon receptor (GCGR), partial (Active), human, recombinant
Glucagon receptor (GCGR), partial (Active), human,...

Item number: CSB-MP009316HU1.1

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 26-136aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AQVMDFLFEK WKLYGDQCHH NLSLLPPPTE LVCNRTFDKY SCWPDTPANT TANISCPWYL PWHHKVQHRF VFKRCGPDGQ WVRGPRGQPW RDASQCQMDG EEIEVQKEVA...
Keywords: GCGR, GL-R, Glucagon receptor, Recombinant Human Glucagon receptor (GCGR), partial (Active)
Application: Active protein
Expressed in: Mammalian cells
Origin: human
MW: 18.1 kD
From 293.00€ *
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Mazdutide
Mazdutide

Item number: Cay40971-1

Mazdutide is a synthetic peptide derivative of the gut peptide hormone oxyntomodulin and a dual agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR). It reduces body weight in both Gcgr-/- and Glp1r-/- mice.Formal Name:...
Keywords: IBI362, LY3305677,...
Application: GLP-1R / GCGR dual agonist, synthetic peptide
CAS 2259884-03-0
MW: 4563.1 D
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L-168,049
L-168,049

Item number: Cay41112-10

L-168,049 is a glucagon receptor (GCGR) antagonist (IC50s = 3.7 and 179 nM in the absence and presence of MgCl2, respectively). It prevents glucagon-induced increases in IL-1beta and IL-6 levels in, and levels secreted from, HepG2 cells when used at a concentration of 3.7 nM. L-168,049 inhibits glucagon-induced...
Keywords: GCGR Antagonist II, Glucagon Receptor Antagonist II,...
Application: GCGR antagonist
CAS 191034-25-0
MW: 467.8 D
From 114.00€ *
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Human GCGR Protein, hFc Tag
Human GCGR Protein, hFc Tag

Item number: DIM-PME100722.10

Recombinant human GCGR protein with C-terminal human Fc tag. GCGR(Ala26-Lys136) hFc(Glu99-Ala330), Protein function: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting...
Keywords: GL-R
Expressed in: Human cells
Origin: human
CAS 12
MW: 39.2 kD
From 95.00€ *
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