128 products were found matching "K04527"!
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Anti-INSR
Item number: ABS-KC-2818.100
Protein function: Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated...
| Keywords: | Anti-Insulin receptor, Anti-IR, Anti-CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Anti-Insulin... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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INSR (human), recombinant protein
Item number: ABS-PP-097.20
| Keywords: | Insulin receptor, IR, CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta],... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 19.5 kD |
From 90.00€
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INSR (human), recombinant protein
Item number: ABS-PP-098.20
| Keywords: | Insulin receptor, IR, CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha, Insulin receptor subunit beta],... |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 51.5 kD |
From 90.00€
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Insulin (human)
Item number: TGM-T8221-25mg
Description: Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patients. Target: IGF-1R. Smiles:...
| Keywords: | INSULIN, Insulin(human) |
| Application: | Targets insulin receptor [EC:2.7.10.1] (INSR, CD220) |
| CAS | 11061-68-0 |
| MW: | 5807.57 D |
From 31.00€
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HNMPA
Item number: TGM-T21761-1mg
Description: HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent protein kinase or protein kinase C activities. Target: IGF-1R. Smiles:...
| Application: | Cell impermeable tyrosine kinase inhibitor |
| CAS | 132541-52-7 |
| MW: | 238.18 D |
From 43.00€
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HNMPA-(AM)3
Item number: TGM-T36584-2mg
Description: HNMPA-(AM)3 inhibits activation of ERK phosphorylation and stimulation of ecdysteroid production by prothyrotropin (PTTH). Furthermore, HNMPA-(AM)3 had inhibitory effects on ecdysteroid production (IC50=14.2 µM) and insulin receptor activity (IC50=14.2 µM and 200 µM, in mosquitoes and mammals,...
| Application: | Cell-permeable insulin receptor inhibitor prodrug |
| CAS | 120944-03-8 |
| MW: | 454.36 D |
195.00€
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GSK1904529A
Item number: TGM-T6003-10mg
Description: GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) . Target: IGF-1R, Apoptosis, Raf, Syk, VEGFR. Smiles: CCc1cc(Nc2nccc(n2)-c2c(nc3ccccn23)-c2ccc(OC)c(c2)C(=O)Nc2c(F)cccc2F)c(OC)cc1N1CCC(CC1)N1CCN(CC1)S(C)(=O)=O. References: Sabbatini P, et al. Clin Cancer Res,...
| Keywords: | GSK 4529 |
| Application: | Insulin receptor / IGF-1R dual inhibitor |
| CAS | 1089283-49-7 |
| MW: | 851.96 D |
From 34.00€
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Insulin Receptor Protein, Human, Recombinant (long...
Item number: TGM-TMPY-01146-100ug
Description: Insulin Receptor Protein, Human, Recombinant (long isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
| Keywords: | HHF5, CD220, insulin receptor |
| MW: | 107 kD |
From 385.00€
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Insulin Receptor Protein, Human, Recombinant (short...
Item number: TGM-TMPY-01149-100ug
Description: Insulin Receptor Protein, Human, Recombinant (short isoform, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 106 kDa and the accession number is P06213-2.
| Keywords: | CD220, Insulin Receptor, HHF5 |
| MW: | 106 kD |
From 599.00€
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Insulin Receptor Protein, Human, Recombinant (long...
Item number: TGM-TMPY-05283-100ug
Description: Insulin Receptor Protein, Human, Recombinant (long isoform, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is P06213-1.
| Keywords: | HHF5, Insulin Receptor, CD220 |
| MW: | 107 kD |
From 304.00€
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Insulin Receptor Protein, Human, Recombinant (His & GST)
Item number: TGM-TMPY-04395-50ug
Description: Insulin Receptor Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.3 kDa and the accession number is P06213-1.
| Keywords: | CD220, insulin receptor, HHF5 |
| MW: | 72.3 kD |
497.00€
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Insulin receptor (INSR), partial, human, recombinant
Item number: CSB-EP011753HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1023-1298aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: ITLLRELGQG SFGMVYEGNA RDIIKGEAET RVAVKTVNES ASLRERIEFL NEASVMKGFT CHHVVRLLGV VSKGQPTLVV MELMAHGDLK SYLRSLRPEA ENNPGRPPPT LQEMIQMAAE IADGMAYLNA...
| Keywords: | INSR, EC=2.7.10.1, Recombinant Human Insulin receptor (INSR), partial |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 47.2 kD |
From 219.00€
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