561 products were found matching "K04456"!
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Anti-AKT3
Item number: ABS-KC-2766.100
Protein function: AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range...
| Keywords: | Anti-RAC-gamma serine/threonine-protein kinase, Anti-Protein kinase Akt-3, Anti-Protein kinase B gamma, Anti-PKB gamma,... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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Anti-AKT3
Item number: ABS-KC-3409.100
Protein function: AKT3 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range...
| Keywords: | Anti-RAC-gamma serine/threonine-protein kinase, Anti-Protein kinase Akt-3, Anti-Protein kinase B gamma, Anti-PKB gamma,... |
| Application: | IP |
| Host: | Mouse |
| Species reactivity: | human |
From 206.00€
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MK-2206 dihydrochloride
Item number: TGM-T1952-2mg
Description: MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent and selective potency. MK-2206 dihydrochloride exhibits antitumor activity. Target: Apoptosis, Akt, Autophagy. Smiles:...
| Keywords: | MK-2206 2HCl |
| Application: | Allosteric Akt inhibitor |
| CAS | 1032350-13-2 |
| MW: | 480.39 D |
From 31.00€
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AKT Kinase Inhibitor
Item number: TGM-T10276-100mg
Description: AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner. Target: Akt. Smiles: C(C)N1C=2C(=C(C#CCO)N=CC2OCCCN)N=C1C=3C(N)=NON3. References: Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor...
| Application: | AKT kinase Inhibitor |
| CAS | 842148-40-7 |
| MW: | 357.37 D |
From 139.00€
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3CAI
Item number: TGM-T14034-100mg
Description: 3CAI is a potent and specific AKT1 and AKT2 inhibitor, demonstrating significant inhibition of AKT in an in vitro kinase assay. It suppressed the expression of AKT direct downstream targets (such as mTOR and GSK3beta) and induced growth inhibition and apoptosis in colon cancer cells. Target: Akt....
| Application: | Akt1 / Akt2 inhibitor |
| CAS | 28755-03-5 |
| MW: | 193.63 D |
From 49.00€
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A-443654
Item number: TGM-T14072-100mg
Description: A-443654, a pan-Akt inhibitor, exhibits equal potency against Akt1, Akt2, and Akt3 within cells (Ki=160 pM). Target: MAPK, Casein Kinase, PKC, Src, Akt, FLT, Chk, GSK-3, CDK, ERK, VEGFR, PKA, S6 Kinase. Smiles: C([C@@H](COC=1C=C(C=NC1)C=2C=C3C(=CC2)NN=C3C)N)C=4C=5C(NC4)=CC=CC5. References:...
| Application: | Potent and selective Akt inhibitor |
| CAS | 552325-16-3 |
| MW: | 397.47 D |
From 83.00€
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AKT-I-1
Item number: TGM-T25017-100mg
Description: AKT-I-1 is a selective and reversible inhibitor of Akt1. Target: Akt. Smiles: CN(C)CC(C)(C)CNc1nn2c(nnc2cc1C1CCC1)-c1ccccc1. References: Zhang Q, et al. Autophagy prevention sensitizes AKTi-1/2-induced anti-hepatocellular carcinoma cell activity in vitro and in vivo. Biochem Biophys Res Commun. 2016 Nov...
| Application: | Akt1 inhibitor |
| CAS | 473382-39-7 |
| MW: | 378.51 D |
From 140.00€
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10-DEBC hydrochloride
Item number: TGM-T21778-1mg
Description: 10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 µM, is identified as a novel anti-tuberculosis compound [1] [2]. Target: Others. Smiles: Cl.ClC1=CC=C2OC=3C=CC=CC3N(C2=C1)CCCCN(CC)CC
| Application: | Akt phosphorylation inhibitor |
| CAS | 925681-41-0 |
| MW: | 381.34 D |
From 122.00€
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Miransertib
Item number: TGM-T3467-100mg
Description: Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor. Target: Akt, Parasite. Smiles: Nc1ncccc1-c1nc2ccc(nc2n1-c1ccc(cc1)C1(N)CCC1)-c1ccccc1. References: Yu Y, et al. PLoS One. 2015, 10(10):e20140479.
| Keywords: | AKT inhibitor 2, ARQ-092 |
| Application: | Targets RAC serine/threonine-protein kinase [EC:2.7.11.1] (AKT) |
| CAS | 1313881-70-7 |
| MW: | 432.52 D |
From 45.00€
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SC66
Item number: TGM-T3132-10mg
Description: SC66 is a AKT inhibitor in HepG2, HA22T/VGH, and PLC/PRF/5 cells (IC50: about 0.75 µg/ml, at 72 h). Target: Apoptosis, Akt. Smiles: O=C1\C(CCC\C1=C/c1ccncc1)=C\c1ccncc1. References: Cusimano A, et al. Oncotarget. 2015 Jan 30,6(3):1707-22.
| Application: | AKT inhibitor |
| CAS | 871361-88-5 |
| MW: | 276.33 D |
From 42.00€
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AKT inhibitor VIII
Item number: TGM-T3346-100mg
Description: AKT inhibitor VIII (AKTi-1/2) is a highly specific inhibitor of Akt1/2, with IC50 values of 58 nM and 210 nM respectively, demonstrating approximately 36-fold greater selectivity for Akt1 over Akt3. Target: Apoptosis, Akt. Smiles: O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(cc2)-c2nc3cc4[nH]cnc4cc3nc2-c2ccccc2)CC1....
| Keywords: | AKTi-1/2 |
| Application: | Akt1/Akt2 inhibitor |
| CAS | 612847-09-3 |
| MW: | 551.64 D |
From 45.00€
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CAY10567
Item number: TGM-T36086-100mg
Description: CAY10567 has a wide range of applications in life science related research. Target: Others. Smiles: OC(=O)C1=CC=C2N=C(C3=CC=CC=C3)C(=NC2=C1)C1=CC=CC=C1
| Application: | Akt1 translocation inhibitor |
| CAS | 32387-96-5 |
| MW: | 326.35 D |
From 67.00€
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