55 products were found matching "K04446"!

NFATc1 inhibitor A04 is an inhibitor of nuclear factor of activated T cells c1 (NFATc1). It inhibits RANKL-induced nuclear translocation of NFATc1 in RAW 264.7 cells when used at concentrations of 1.5 or 2 µM. NFATc1 inhibitor A04 reduces RANKL-induced differentiation of RAW 264.7 cells into osteoclasts (IC50 = 1.57...

Description: NFAT Inhibitor (VIVIT peptide) is a cell-permeable compound that selectively inhibits the calcineurin-mediated dephosphorylation of NFAT. Target: Others. Smiles:...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: NFATC1. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NFATC1. Antigen Species: Human

0.5mg/ml if reconstituted with 0.2ml sterile DI water. NFATC1 (Nuclear factor of activated T-cells, cytoplasmic 1), also known as NFATC or NFAT2, is a protein that in humans is encoded by the NFATC1 gene. And it is also a component of the nuclear factor of activated T cells DNA-binding transcription complex. The...

NFAT inhibitor is a peptide inhibitor of the transcription factor nuclear factor of activated T cells (NFAT). It binds to the NFAT recognition site on the protein phosphatase calcineurin (IC50 = 25 pM) but does not inhibit calcineurin phosphatase activity when used at a concentration of 100 µM. NFAT inhibitor...

The NFAT Reporter - Jurkat Cell Line contains a firefly luciferase gene under the control of the NFAT response element stably integrated into Jurkat cells. This cell line has been validated for response to thapsigargin, ionomycin, and phorbol 12-myristate 13-acetate (PMA). It is useful as a control cell line for...

Protein function: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed...

The NFAT Reporter - Hek293 cell line contains a firefly luciferase gene under the control of NFAT response element stably integrated into Hek293 cells. This cell line is validated for the response to the stimulation of phorbol 12-myristate 13-acetate (PMA) with ionomycin.

Anti-NFATc1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-NFATc1 from human and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-NFATc1 from other sources has not been determined. Protein function: Plays a role...

NFAT activation inhibitor III is a cell-permeant inhibitor of signaling through nuclear factor of activated T cells (NFAT). It binds the substrate recognition site of the phosphatase calcineurin (Kd = 0.8 µM), preventing it from binding and dephosphorylating NFAT. NFAT activation inhibitor III blocks the nuclear...