- Search results for K04411
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36 products were found matching "K04411"!
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Item number: TGM-T4212-2mg
Description: XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2. Target: Hippo pathway. Smiles: CN1c2ccsc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12. References: Fan F, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Sci Transl Med....
Application: | STK3 / STK4 inhibitor |
CAS | 2061980-01-4 |
MW: | 416.48 D |
From 48.00€
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Item number: TGM-TMPY-04398-50ug
Description: Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates...
Keywords: | KRS2, serine/threonine kinase 4, TIIAC, YSK3, MST1 |
MW: | 58 kD |
497.00€
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Item number: CSB-PA168071.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: STK4. Antigen Species: Human
Keywords: | Anti-STK4, Anti-KRS2, EC=2.7.11.1, Kinase responsive to stress antibody, Krs2 antibody, Mammalian STE20 like protein... |
Application: | ELISA, WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 167.00€
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Item number: CSB-PA192084.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: STK4. Antigen Species: Human
Keywords: | Anti-STK4, Anti-KRS2, EC=2.7.11.1, Kinase responsive to stress antibody, Krs2 antibody, Mammalian STE20 like protein... |
Application: | ELISA, WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 167.00€
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Item number: CSB-PA230165.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
Keywords: | Anti-phospho-STK4, Anti-phospho-KRS2, EC=2.7.11.1, Kinase responsive to stress antibody, Krs2 antibody, Mammalian STE20... |
Application: | ELISA, WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
340.00€
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Item number: A300-465A
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
Keywords: | Anti-STK4, Anti-KRS2, EC=2.7.11.1 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
630.00€
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Item number: A300-466A
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
Keywords: | Anti-STK4, Anti-KRS2, EC=2.7.11.1 |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 178.00€
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Item number: Cay22083-25
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 µM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2...
Keywords: | 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-benzenesulfonamide |
Application: | STK3 / STK4 inhibitor |
CAS | 2061980-01-4 |
MW: | 416.5 D |
From 35.00€
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Item number: BPS-40017
Human STK4 (serine/threonine kinase 4), also known as MST-1 (Mammalian STE20-like protein kinase 1) or KRS2, GenBank Accession No. NM_006282, amino acids 2-488(end), with N-terminal GST-tag, MW=81.5 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
Keywords: | STK4, KRS2, EC=2.7.11.1, |
Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Expressed in: | Baculovirus |
Origin: | human |
MW: | 81.5 kD |
536.00€
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Item number: E-AB-13112.120
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK...
Keywords: | Anti-KRS2, Anti-STK4, EC=2.7.11.1, STK3/STK4 Polyclonal Antibody |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 89.00€
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Item number: NSJ-F50888-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A...
Keywords: | Anti-STK4, Anti-KRS2, EC=2.7.11.1, MST1 Antibody (Mammalian STE20-like protein kinase 1) |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 350.00€
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Item number: E-AB-16302.120
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK...
Keywords: | Anti-KRS2, Anti-STK4, EC=2.7.11.1, STK3/STK4 Polyclonal Antibody |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 89.00€
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