337 products were found matching "K04371"!
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Anti-MAPK3
Item number: ABS-KC-4086.100
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF....
| Keywords: | Anti-Mitogen-activated protein kinase 3, Anti-MAP kinase 3, Anti-MAPK 3, Anti-ERT2, Anti-Extracellular signal-regulated... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human, rat, mouse |
From 206.00€
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Anti-MAPK3
Item number: ABS-KC-4213.100
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF....
| Keywords: | Anti-Mitogen-activated protein kinase 3, Anti-MAP kinase 3, Anti-MAPK 3, Anti-ERT2, Anti-Extracellular signal-regulated... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human, rat, mouse |
From 206.00€
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Anti-MAPK3
Item number: ABS-KC-4219.100
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF....
| Keywords: | Anti-Mitogen-activated protein kinase 3, Anti-MAP kinase 3, Anti-MAPK 3, Anti-ERT2, Anti-Extracellular signal-regulated... |
| Application: | IHC |
| Host: | Mouse |
| Species reactivity: | human, rat, mouse |
From 206.00€
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Anti-ERK 1/2
Item number: E-D-AB-10257L.100
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases,also known as extracellular signal-regulated kinases (ERKs),act in a signaling cascade that regulates various cellular processes such as proliferation,differentiation,and cell cycle progression in response to a variety of...
| Keywords: | Anti-ERT2, Anti-MNK1, Anti-Erk1, Anti-Mapk3, Anti-ERK-1, Anti-MAPK 3, Anti-p44-MAPK, Anti-p44-ERK1, EC=2.7.11.24, Anti-MAP... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | mouse |
From 109.00€
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FR 180204
Item number: TGM-T1956-100mg
Description: FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2. Target: ERK, Apoptosis. Smiles: NC=1C2=CC(C=3C(=NN4C3C=CC=C4)C5=CC=CC=C5)=NN=C2NN1. References: Ohori M, et al. Biochem Biophys Res Commun. 2005, 336(1), 357-363.
| Keywords: | FR180204 |
| Application: | Cell-permeable ERK1 / ERK2 inhibitor |
| CAS | 865362-74-9 |
| MW: | 327.34 D |
From 37.00€
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Ravoxertinib
Item number: TGM-T6511-100mg
Description: Ravoxertinib (GDC-0994) is an efficacious, orally available ERK1/2 inhibitor with an IC50 of 1.1/0.3 nM. Target: ERK. Smiles: Cn1nccc1Nc1nccc(n1)-c1ccn([C@H](CO)c2ccc(Cl)c(F)c2)c(=O)c1. References: AACR2014. Abstract.
| Keywords: | GDC-0994 |
| Application: | Targets mitogen-activated protein kinase 1/3 [EC:2.7.11.24] (ERK, MAPK1_3) |
| CAS | 1453848-26-4 |
| MW: | 440.86 D |
From 34.00€
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ERK1/2 inhibitor 6
Item number: TGM-T64147-100mg
Description: ERK1/2 inhibitor 6 is a potent inhibitor of ERK1/2, showing potential for studying or preventing cancer, inflammation, and other proliferative diseases. Target: Others. Smiles: O=C1C=2N(C=C(C2)C3=NC(NC4CCOCC4)=NC=C3Cl)N=CN1[C@@H](C(N[C@H](CO)C5=CC(OC)=CC(F)=C5)=O)C
| Application: | ERK1/2 inhibitor |
| CAS | 2634816-13-8 |
| MW: | 586.01 D |
From 1,520.00€
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ERK1/2 inhibitor 5
Item number: TGM-T64155-100mg
Description: ERK1/2 inhibitor 5 is a potent inhibitor of ERK1/2, with potential applications in investigating or preventing cancer, inflammation, and other proliferative diseases. Target: Others. Smiles: O=C1N2C(=CC(=C2)C3=NC(NC4CCOCC4)=NC=C3Cl)CCN1[C@@H](C(N[C@H](CO)C5=CC(OC)=CC(F)=C5)=O)C
| Application: | ERK1/2 inhibitor |
| CAS | 2560552-75-0 |
| MW: | 587.04 D |
From 1,520.00€
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ERK1/2 inhibitor 8
Item number: TGM-T63331-100mg
Description: ERK1/2 inhibitor 8 is a potent ERK inhibitor, targeting ERK2 with an IC50 of 0.48 nM. Target: Others. Smiles: C(N1C2(C3=C(C1=O)N=C(S3)C4=NC(NC=5N(C)N=CC5)=NC=C4C)COC2)C6=CC(Cl)=CC=C6
| Application: | ERK1/2 inhibitor |
| CAS | 2648368-43-6 |
| MW: | 493.97 D |
From 2,142.00€
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ERK1/2 inhibitor 7
Item number: TGM-T62933-100mg
Description: ERK1/2 inhibitor 7 is a potent inhibitor of ERK, with an IC50 of 0.94 nM for ERK2. Target: Others. Smiles: Cc1cnc(Nc2ccnn2C)nc1-c1nc2C(=O)N(Cc3cccc(F)c3)C(C)(C)c2s1
| Application: | ERK1/2 inhibitor |
| CAS | 2648455-13-2 |
| MW: | 463.53 D |
From 1,400.00€
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SCH772984
Item number: TGM-T6066-100mg
Description: SCH772984 is an ERK inhibitor that inhibits ERK1 and ERK2 (IC50=4/1 nM) and is highly selective and ATP-competitive. SCH772984 exhibits antitumor activity against BRAF or RAS mutant cells. Target: MEK, ERK. Smiles: O=C(CN1CC[C@H](C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1....
| Application: | Potent ERK1 / ERK2 inhibitor |
| CAS | 942183-80-4 |
| MW: | 587.67 D |
From 48.00€
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SCH 772984
Item number: Cay19166-1
The extracellular regulated kinases 1 and 2 (ERK1/2) are functionally redundant kinases activated by a variety of growth factors and mitogens. SCH 772984 is a potent inhibitor of ERK1 and ERK2 (IC50s = 4 and 1 nM, respectively). It is highly selective, with only seven kinases of 300 tested showing more than 50%...
| Keywords: | (3R)-1-[2-oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxa... |
| Application: | Potent ERK1 / ERK2 inhibitor |
| CAS | 942183-80-4 |
| MW: | 587.7 D |
From 52.00€
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