748 products were found matching "K04361"!
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Epidermal growth factor receptor (EGFR), partial, human,...
Item number: CSB-EP007479HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 25-645aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: LEEKKVCQGT SNKLTQLGTF EDHFLSLQRM FNNCEVVLGN LEITYVQRNY DLSFLKTIQE VAGYVLIALN TVERIPLENL QIIRGNMYYE NSYALAVLSN YDANKTGLKE...
| Keywords: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 73.6 kD |
From 213.00€
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Epidermal growth factor receptor (EGFR), partial, human,...
Item number: CSB-EP007479HU3.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 669-684aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Target Protein Sequence: RRRHIVRKRT LRRLLQ. Purity: Greater than 85% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a....
| Keywords: | ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 22.2 kD |
From 213.00€
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RX-518
Item number: Cay40922-10
RX-518 is an inhibitor of EGFR. It inhibits the growth of A431, H1975, and HCC827 cancer cells expressing wild-type EGFR, EGFR L858R/T790M, and EGFR del19, respectively (GI50s = 5, 10, and 689 nM, respectively).Formal Name:...
| Keywords: | CK-101, Olafertinib,... |
| Application: | EGFR inhibitor |
| CAS | 1660963-42-7 |
| MW: | 530.6 D |
From 114.00€
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Human EGFR Protein, His Tag
Item number: DIM-PME100099.10
Recombinant human EGFR Protein with C-terminal 6×His tag. EGFR(Leu25-Ser645) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725,...
| Keywords: | EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 69.4 kD |
From 115.00€
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Anti-EGFRVIII antibody(2E12), IgG1 Chimeric mAb
Item number: DIM-DMC101040.10
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Keywords: | Anti-EGFR, Anti-RBB, Anti-RBB1, Anti-ER1, Anti-IG61, Anti-ENA, Anti-EGFRVIII antibody(2E12), IgG1 Chimeric mAb |
| Host: | Rabbit |
| Species reactivity: | human |
| CAS | 12 |
From 139.00€
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Human EGFRVIII Protein, His Tag
Item number: DIM-PME101321.10
Recombinant Human EGFRVIII Protein with C-terminal 6×His tag. EGFRVIII(Leu25-Ser645 ?267aa) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960,...
| Keywords: | EGFR, ERBB, ERBB1, HER1, PIG61, mENA |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 39.5 kD |
From 98.00€
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Cynomolgus EGFR Protein, His Tag
Item number: DIM-PME-C100036.10
Recombinant Cynomolgus EGFR protein with C-terminal 10×His tag. EGFR(Leu25-Ser645) 10×His tag
| Keywords: | ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2 |
| Expressed in: | Human cells |
| Origin: | Cynomolgus |
| MW: | 70.0 kD |
From 168.00€
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Mouse EGFR Protein, His Tag
Item number: DIM-PME-M100062.10
Recombinant mouse EGFR protein with C-terminal 6×His tag. Mouse EGFR(Leu25-Ser647) 6×His tag, Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:8404850). Known ligands...
| Keywords: | Epidermal growth factor receptor, Egfr |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | 70.1 kD |
From 144.00€
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Human EGFR ELISA Kit
Item number: ARG83044.96
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin,...
| Keywords: | ERBB, Proto-oncogene c-ErbB-1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, Receptor tyrosine-protein... |
| Application: | ELISA |
| Species reactivity: | human |
638.00€
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Erlotinib
Item number: Cay10483-250
Erlotinib is an EGFR inhibitor (Ki = 2.7 nM). It is greater than 1,000-fold selective for EGFR over Src and Abl at 0.1 µM. Erlotinib induces caspase-3 and -7 activity in NCI H358 non-small cell lung cancer (NSCLC) cells when used at a concentration of 1 µM. Erlotinib (25 mg/kg) reduces EGF-induced EGFR...
| Keywords: | NSC 718781, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine |
| Application: | Tyrosine kinase inhibitor |
| CAS | 183321-74-6 |
| MW: | 393.4 D |
From 43.00€
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Human anti-EGFR Antibody, Clone C225 (Cetuximab Biosimilar)
Item number: CR-C10021-100UG
Storage buffer: Azide free-phosphate buffered saline, 0.2 µm filter sterilized. Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536)....
| Keywords: | Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
| Application: | ELISA, FC, IHC, IF |
| Host: | Human |
| Species reactivity: | Human |
From 392.00€
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AZ 7550 (hydrochloride)
Item number: Cay40753-1
AZ 7550 is an active metabolite of AZ 9291 (Cay-16237). It inhibits the insulin-like growth factor 1 receptor (IGF-1R) in a cell-free assay (IC50 = 1.6 µM). It inhibits EGFR autophosphorylation in H1975 and PC-9 cells expressing the respective constitutively active mutants EGFRT790M/L858R and EGFRExon19del (IC50s =...
| Keywords: | N-[4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]-2-[methyl[2-(methylamino)ethyl]amino]phenyl]-2-propenamid... |
| Application: | AZ 9291 active metabolite, mutant-selective EGFR inhibitor |
| MW: | 485.6 D |
From 34.00€
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