26 products were found matching "K04332"!
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Anti-PTGDR
Item number: ATA-HPA046586.100
Polyclonal Antibody against Human PTGDR, Gene description: prostaglandin D2 receptor, Alternative Gene Names: DP, DP1, PTGDR1, Validated applications: ICC, WB, Uniprot ID: Q13258, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: Receptor for prostaglandin D2...
| Keywords: | Anti-PTGDR, Anti-PGD receptor, Anti-PGD2 receptor, Anti-Prostanoid DP receptor, Anti-Prostaglandin D2 receptor |
| Application: | WB, ICC |
| Host: | Rabbit |
| Species reactivity: | human |
477.00€
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Setipiprant
Item number: TGM-T3520-100mg
Description: Setipiprant (ACT-129968) is an orally available, selective CRTH2 antagonist (IC50: 6.0 nM). CRTH2, a G protein-coupled receptor for prostaglandin (PGD2), mediates key inflammatory responses related to allergy and asthma. PGD2, produced by mast cells, binds to CRTH2 on blood-borne cells, inducing...
| Keywords: | ACT-129968, KYTH-105 |
| Application: | Targets prostaglandin D2 receptor (PTGDR) |
| CAS | 866460-33-5 |
| MW: | 402.42 D |
From 31.00€
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Fevipiprant
Item number: TGM-T3965-100mg
Description: Fevipiprant (NVP-QAW039) is a selective, potent, reversible competitive CRTh2 antagonist. Target: GPR, Prostaglandin Receptor. Smiles: Cc1c(CC(O)=O)c2cccnc2n1Cc1ccc(cc1C(F)(F)F)S(C)(=O)=O. References: Sykes DA, et al. Fevipiprant (QAW039), a Slowly Dissociating CRTh2 Antagonist with the Potential for...
| Keywords: | QAW039, NVP-QAW039 |
| Application: | Targets prostaglandin D2 receptor (PTGDR) |
| CAS | 872365-14-5 |
| MW: | 426.41 D |
From 30.00€
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AL 6598
Item number: TGM-T38113-10mg
Description: Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2alpha and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 µM and...
| Application: | PGD2 receptor agonist |
| CAS | 170291-06-2 |
| MW: | 431.01 D |
From 292.00€
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Asapiprant
Item number: TGM-T5386-100mg
Description: Asapiprant (S-555739) is a potent and selective DP1 receptor antagonist (Ki: 0.44 nM). It exhibited high affinity and selectivity for the DP1 receptor. Target: Prostaglandin Receptor. Smiles: CC(C)Oc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1ccc(-c2ncco2)c(OCC(O)=O)c1. References: Takahashi G, et al. Effect of the...
| Application: | Prostaglandin D2 receptor (PTGDR) antagonist |
| CAS | 932372-01-5 |
| MW: | 501.55 D |
From 34.00€
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Vidupiprant
Item number: TGM-T17232-100mg
Description: Vidupiprant (AMG 853) is an effective dual antagonist of CRTH2 and prostanoid D receptor with IC50s of 8 nM and 35 nM in human plasma. Vidupiprant can be used in studies about the treatment of asthma. Target: Prostaglandin Receptor. Smiles:...
| Keywords: | AMG 853 |
| Application: | Targets prostaglandin D2 receptor (PTGDR) |
| CAS | 1169483-24-2 |
| MW: | 609.49 D |
From 60.00€
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Laropiprant
Item number: TGM-T15712-100mg
Description: Laropiprant (MK-0524) is a potent and selective antagonist of prostaglandin D2 (PGD2) receptor (DP) such as and DP/DP1 receptor(Ki = 0.57 nM) and TP Receptor(Ki = 2.95 nM). Target: Prostaglandin Receptor. Smiles: CS(=O)(=O)c1cc(F)cc2c3CC[C@H](CC(O)=O)c3n(Cc3ccc(Cl)cc3)c12. References: Sturino CF, et al....
| Keywords: | MK-0524 |
| Application: | Targets prostaglandin D2 receptor (PTGDR) |
| CAS | 571170-77-9 |
| MW: | 435.9 D |
From 33.00€
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Prostaglandin D2 receptor (PTGDR), partial, human,...
Item number: CSB-EP621658HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 217-262aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: CNLGAMRNLY AMHRRLQRHP RSCTRDCAEP RADGREASPQ PLEELD. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test....
| Keywords: | PTGDR, PGD receptor, PGD2 receptor, Prostanoid DP receptor, Prostaglandin D2 receptor, Recombinant Human Prostaglandin D2... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 12.8 kD |
From 292.00€
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Anti-PTGDR
Item number: CSB-PA040057.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-PTGDR, Anti-PGD receptor, Anti-PGD2 receptor, Anti-Prostanoid DP receptor, Anti-Prostaglandin D2 receptor, AS 1... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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Anti-DP1 Receptor
Item number: Cay101640-1
Prostaglandin D2 (PGD2) binds to two receptor subtypes: DP1 and CRTH2/DP2, which are both membrane-bound G protein-coupled receptors (GPCRs) but do not have significant homology and are differentially expressed. The DP1 receptor is expressed in various tissues and cells including the brain, spleen, lungs, bone...
| Keywords: | Anti-Ptgdr, Anti-PGD receptor, Anti-PGD receptor, Anti-PGD2 receptor, Anti-PGD2 receptor, Anti-Prostanoid DP receptor,... |
| Application: | IF, WB |
| Host: | Rabbit |
| Species reactivity: | human, murine, rat |
431.00€
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AZD 1981
Item number: Cay20763-5
AZD 1981 is a DP2/CRTH2 receptor antagonist (IC50 = 3.98 nM). It is selective for DP2 over a panel of receptors, ion channels, transporters, and enzymes, including DP1, COX-1, and COX-2, at 10 µM. AZD 1981 (3-100 nM) inhibits increases in the expression of CD11b, a cell adhesion molecule, induced by...
| Keywords: | 4-(acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-1H-indole-1-acetic acid |
| Application: | PGD2 receptor antagonist |
| CAS | 802904-66-1 |
| MW: | 388.9 D |
From 66.00€
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Fevipiprant
Item number: Cay20263-1
Fevipiprant is a DP2/CRTH2 antagonist (Ki = 1.05 nM). It reduces shape change of eosinophils induced by prostaglandin D2 (PGD2, Cay-12010) with IC50 values of 0.4 and 0.44 nM for isolated human eosinophils and human whole blood, respectively. Fevipiprant inhibits PGD2-induced release of IL-5 and IL-13 in isolated...
| Keywords: | NVP-QAW039, QAW039, 2-methyl-1-[[4-(methylsulfonyl)-2-(trifluoromethyl)phenyl]methyl]-1 H -pyrrolo[2,3b]pyridine-3-acetic... |
| Application: | Prostaglandin D2 receptor antagonist |
| CAS | 872365-14-5 |
| MW: | 426.4 D |
From 78.00€
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