43 products were found matching "K04298"!
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2-oxo Clopidogrel
Item number: TGM-T36222-1mg
Description: 2-oxo Clopidogrel is an intermediary metabolite of clopidogrel . Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and...
| Application: | P2RY12 irreversible inhibitor prodrug |
| CAS | 109904-27-0 |
| MW: | 337.82 D |
From 120.00€
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AZD1283
Item number: TGM-T3536-100mg
Description: AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED50 values of 3.0 and 10 µg/kg/min, respectively. The doses induced the increase...
| Application: | P2Y purinoceptor 12, P2Y12 antagonist |
| CAS | 919351-41-0 |
| MW: | 470.54 D |
From 32.00€
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(±)-Clopidogrel (hydrochloride)
Item number: TGM-T35431-10mg
Description: Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite...
| Application: | P2Y12 receptor antagonist |
| CAS | 130209-90-4 |
| MW: | 358.28 D |
From 337.00€
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Regrelor disodium
Item number: TGM-T34280-100mg
Description: Regrelor disodium (INS 50589) is a P2Y12 receptor antagonist that prevents thrombosis, effectively inhibits vascular smooth muscle cell contraction, curbs cell proliferation, and reduces inflammation. Target: P2Y Receptor. Smiles:...
| Keywords: | Regrelor, INS 50589, INS50589, INS-50589, Regrelor sodium |
| Application: | Targets P2Y purinoceptor 12 (P2RY12) |
| CAS | 676251-22-2 |
| MW: | 576.41 D |
From 190.00€
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Farnesyl Pyrophosphate ammonium salt
Item number: TGM-T37775-1mg
Description: Farnesyl Pyrophosphate ammonium (Farnesyl diphosphate ammonium) is a metabolic intermediate of the MVA pathway that acts as a newly identified danger signal to trigger acute cell death and induce neuronal loss in stroke. Target: Others. Smiles:...
| Keywords: | FPP ammonium, Farnesyl diphosphate ammonium, (E,E)-Farnesyl pyrophosphate ammonium |
| Application: | P2Y12 receptor antagonist |
| CAS | 116057-57-9 |
| MW: | 433.42 D |
From 166.00€
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Clopidogrel HCl
Item number: TGM-T71254-100mg
Description: Clopidogrel HCl is the salt form of Clopidogrel (free base), an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) binding to its receptor and of the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. Target: Others. Smiles:...
| Application: | Targets P2Y purinoceptor 12 (P2RY12) |
| CAS | 120202-65-5 |
| MW: | 358.28 D |
From 1,491.00€
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Ticagrelor-d7
Item number: TGM-TMIJ-0139-1mg
Description: Ticagrelor-d7 is a deuterated compound of Ticagrelor. Ticagrelor has a CAS number of 274693-27-5. Ticagrelor, produced by AstraZeneca, is an inhibitor of platelet aggregation. Unlike clopidogrel, ticagrelor is not a prodrug required metabolic activation. The drug was approved for use in the European...
| Application: | Internal standard, GC-MS, LC-MS |
| CAS | 1265911-55-4 |
| MW: | 529.61 D |
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P2Y purinoceptor 12 (P2ry12), mouse, recombinant
Item number: CSB-CF861428MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-347aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MDVPGVNTTS ANTTFSPGTS TLCVRDYKIT QVLFPLLYTV LFFAGLITNS LAMRIFFQIR SKSNFIIFLK NTVISDLLMI LTFPFKILSD AKLGAGPLRT LVCQVTSVTF...
| Keywords: | P2Y12, P2ry12, P2Y purinoceptor 12, Recombinant Mouse P2Y purinoceptor 12 (P2ry12) |
| Application: | Activity not tested |
| Expressed in: | E.coli in vitro |
| Origin: | mouse |
| MW: | 45.5 kD |
From 1,413.00€
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P2Y purinoceptor 12 (P2RY12), human, recombinant
Item number: CSB-CF861997HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-342aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MQAVDNLTSA PGNTSLCTRD YKITQVLFPL LYTVLFFVGL ITNGLAMRIF FQIRSKSNFI IFLKNTVISD LLMILTFPFK ILSDAKLGTG PLRTFVCQVT SVIFYFTMYI...
| Keywords: | P2Y12, HORK3, SP1999, ADPG-R, P2RY12, P2T(AC), P2Y(AC), P2Y(cyc), P2Y(ADP), P2Y purinoceptor 12, ADP-glucose receptor,... |
| Application: | Activity not tested |
| Expressed in: | E.coli in vitro |
| Origin: | human |
| MW: | 42.2 kD |
From 1,413.00€
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Ticagrelor
Item number: Cay15425-5
Ticagrelor is a reversible antagonist of the platelet purinergic P2Y12 receptor (Ki = 14 nM, IC50 = 1.8 µM), which is the main receptor responsible for ADP-induced platelet aggregation. It functions by directly changing the conformation of the P2Y12 receptor to inhibit ADP binding. Formulations containing ticagrelor...
| Keywords: | AR-C 126532XX, AZD 6140,... |
| Application: | P2Y12 receptor antagonist |
| CAS | 274693-27-5 |
| MW: | 522.6 D |
From 43.00€
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Farnesyl Pyrophosphate (ammonium salt)
Item number: Cay63250-1
Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and used in the biosynthesis of terpenes, terpenoids, and sterols. It also serves as a donor in post-translational isoprenylation of proteins. FPP has been identified as an antagonist of P2Y12 receptors (IC50 = 45 µM), attenuating platelet...
| Keywords: | FPP, P-[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl] ester-diphosphoric acid, triammonium salt |
| Application: | P2Y12 receptor antagonist |
| CAS | 116057-57-9 |
| MW: | 433.4 D |
From 92.00€
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Human P2RY12 (Purinergic Receptor P2Y, G Protein Coupled...
Item number: ELK-ELK4385.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human P2RY12. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human P2RY12....
| Keywords: | P2Y12, HORK3, SP1999, P2RY12, ADPG-R, P2Y(AC), P2T(AC), P2Y(cyc), P2Y(ADP), P2Y purinoceptor 12, ADP-glucose receptor,... |
| Application: | ELISA |
| Species reactivity: | human |
From 365.00€
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