38 products were found matching "K04290"!
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TY-52156
Item number: TGM-T17183-5mg
Description: TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM). Target: LPL Receptor, S1P Receptor. Smiles: CC(C)(C)C(=O)C(\NNc1ccc(Cl)cc1)=N\c1ccc(Cl)cc1
| Application: | S1PR3 antagonist |
| CAS | 934369-14-9 |
| MW: | 364.27 D |
From 34.00€
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CYM-5541
Item number: TGM-T3961-100mg
Description: CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist. Target: S1P Receptor, LPL Receptor. Smiles: O=C(N(C1CCCCC1)C1CCCCC1)c1cc(on1)C1CC1. References: Jo E, et al. Novel selective allosteric and bitopic ligands for the S1P(3) receptor. ACS Chem Biol. 2012 Dec 21,7(12):1975-83.
| Keywords: | CID-17253208, ML249, CYM 5541 |
| Application: | Allosteric agonist of S1P3 |
| CAS | 945128-26-7 |
| MW: | 316.44 D |
From 33.00€
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Anti-S1PR3
Item number: CSB-PA002248.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-EDG3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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Anti-S1PR3
Item number: CSB-PA007902.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-EDG3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
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Anti-S1PR3
Item number: CSB-PA273834.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: S1PR3. Antigen Species: Human
| Keywords: | Anti-EDG3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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Anti-S1PR3
Item number: CSB-PA682555.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: S1PR3. Antigen Species: Human
| Keywords: | Anti-EDG3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-Sphingosine 1-phosphate receptor 3,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 167.00€
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CYM 5541
Item number: Cay15190-5
The sphingosine 1-phosphate (S1P) receptor S1P3 has roles in vasodilation, epithelial barrier function, cardioprotection, fibrosis, immunity, and inflammation. CYM 5541 is a selective, allosteric agonist of S1P3 (EC50 = 72-132 nM). It less effectively activates S1P1 (EC50 = 28-38 µM) and is ineffective at S1P2,...
| Keywords: | CID-17253208, ML-249, N,N-dicyclohexyl-5-cyclopropyl-3-isoxazolecarboxamide |
| Application: | Allosteric agonist of S1P3 |
| CAS | 945128-26-7 |
| MW: | 316.4 D |
From 85.00€
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TY 52156
Item number: Cay19119-5
TY 52156 is a selective sphingosine-1-phosphate receptor 3 (SIP3) antagonist (Ki = 110 nM). It preferentially inhibits the S1P-induced increase in intracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell expressing S1P1, S1P2, or S1P4. TY 52156 has been shown to suppress FTY720-induced S1P3...
| Keywords: | N-(4-chlorophenyl)-3,3-dimethyl-2-oxobutanimidic acid, 2-(4-chlorophenyl)hydrazide |
| Application: | S1PR3 antagonist |
| CAS | 934369-14-9 |
| MW: | 364.3 D |
From 44.00€
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Anti-S1P3
Item number: Cay10006373-1
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G-protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P3 couples to Gi/o-ERK, Gq-PLC, and G12/13-Rho axes to mediate S1P-induced cell proliferation, survival, migration, and related signaling...
| Keywords: | Anti-EDG3, Anti-S1P3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-S1P... |
| Application: | ICC, WB |
| Host: | Rabbit |
431.00€
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VPC 23019
Item number: Cay13240-500
Sphingosine-1-phosphate (S1P, Cay-62570) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1,...
| Keywords: | (R)-2-amino-3-((3-octylphenyl)amino)-3-oxopropyl dihydrogen phosphate |
| Application: | Competitive S1P1 / S1P3 receptor antagonist |
| CAS | 449173-19-7 |
| MW: | 372.4 D |
From 55.00€
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Lipid-based Drug Delivery Tools
Sphingosine-1-phosphate (d16:1)
Item number: Cay9002921-5
C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P, Cay-62570) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma...
| Keywords: | C16 S1P, C16 Sphingosine-1-phosphate, S1P (d16:1), 2S-amino-1-(dihydrogen phosphate), 4E-hexadecene-1,3R-diol |
| Application: | S1PR1/S1PR2/S1PR3 ligand |
| CAS | 709026-60-8 |
| MW: | 351.4 D |
From 280.00€
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Human S1P3 / EDG5 ELISA Kit
Item number: G-HUFI00627.96
| Application: | ELISA |
| Species reactivity: | human |
641.00€
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