107 products were found matching "K04278"!
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JWH 133
Item number: Cay10005428-1
JWH 133 is a synthetic cannabinoid (CB) that is over 200-fold selective for the peripheral CB2 receptor (Ki = 3.4 nM) over the central CB1 receptor (Ki = 677 nM). It inhibits the growth of tumors in mice, increasing apoptosis and impairing angiogenesis. JWH 133 also suppresses inflammation in experimental colitis...
| Keywords: | 3-(1,1-dimethylbutyl)-6aR,7,10,10aR-tetrahydro-6,6,9-trimethyl-6H-dibenzo[b,d]pyran |
| Application: | Analytical reference standard, peripheral CB2 receptor selective |
| CAS | 259869-55-1 |
| MW: | 312.5 D |
From 60.00€
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Magnolol
Item number: TGM-T3000-100mg
Description: Magnolol (5,5'-Diallyl-2,2'-biphenyldiol) is a dual agonist of RXRalpha( EC50=10.4 µM) and PPARgamma(EC50=17.7 µM). It blocks TNF-alpha-induced NF-KB activation. Target: NF-kappaB, PPAR, p53, Autophagy, Antibacterial, Retinoid Receptor. Smiles: OC=1C(=CC(CC=C)=CC1)C2=CC(CC=C)=CC=C2O. References: Ai...
| Keywords: | NSC 293099, 5,5'-Diallyl-2,2'-biphenyldiol |
| Application: | Metabolic studies, CB2 receptor agonist |
| CAS | 528-43-8 |
| MW: | 266.33 D |
From 39.00€
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JWH 072
Item number: TGM-T32331-10mg
Description: JWH 072 , known as synthetic cannabinoid (CB), displays a higher affinity to the peripheral CB2 receptor (Ki = 170 nM) than the central CB1 receptor (Ki = 1,050 nM). Its physiological and toxicological properties are still on study. Target: Others. Smiles:...
| Keywords: | JWH-072, JWH072 |
| Application: | Synthetic cannabinoid |
| CAS | 209414-06-2 |
| MW: | 313.39 D |
From 171.00€
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Vicasinabin
Item number: TGM-T38912-5mg
Description: Vicasinabin, a potent agonist of cannabinoid receptor 2 (CB2), exhibits promising potential for researching chronic pain, atherosclerosis, regulation of bone mass, neuroinflammation, and related human diseases. Target: Others. Smiles: Cn1nnnc1Cn1nnc2c(nc(nc12)C(C)(C)C)N1CC[C@H](O)C1. References:...
| Application: | Targets cannabinoid receptor 2 (CNR2) |
| CAS | 1433361-02-4 |
| MW: | 358.41 D |
773.00€
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Bay 59-3074
Item number: TGM-T3699-100mg
Description: Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM). In rat models of chronic neuropathic and inflammatory pain, it displays anti-hyperalgesic and antiallodynic properties. Target: Cannabinoid Receptor. Smiles: FC(F)(F)CCCS(=O)(=O)Oc1cccc(Oc2cccc(c2C#N)C(F)(F)F)c1. References: De Vry J,...
| Application: | CB1 / CB2 partial agonist |
| CAS | 406205-74-1 |
| MW: | 453.36 D |
From 39.00€
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(R)-AM1241
Item number: TGM-T38030-10mg
Description: (R)-AM1241 binds to cannabinoid (CB) receptors and has greater than 100-fold selectivity for the CB2 over the CB1 receptor (Kis = 15 and 5,000 nM, respectively, in a membrane assay using human receptors). (R)-AM1241 acts as an agonist at human CB2 receptors (EC50 = 118 nM) but an inverse agonist at rat...
| Keywords: | (R)-AM1241 |
| Application: | Cannabinoid receptor agonist |
| CAS | 444912-51-0 |
| MW: | 503.33 D |
From 154.00€
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(±)-WIN 55,212 (mesylate)
Item number: TGM-T38199-10mg
Description: (±)-WIN 55,212-2 is a potent aminoalkylindole cannabinoid (CB) receptor agonist with a Ki value of 62.3 and 3.3 nM for human recombinant central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively. In contrast, the enantiomer (-)-WIN 55,212-3 acts a partial inverse agonist at CB1...
| Application: | CB receptor agonist |
| CAS | 137795-17-6 |
| MW: | 522.61 D |
From 96.00€
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GW 405833
Item number: TGM-T7705-100mg
Description: GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selective. Target: Cannabinoid Receptor. Smiles: COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1. References: Li A L , Carey L M , Mackie K , et al. The cannabinoid CB 2 agonist GW405833 suppresses inflammatory and neuropathic pain...
| Keywords: | L-768242 |
| Application: | Partial CB2 receptor agonist |
| CAS | 180002-83-9 |
| MW: | 447.35 D |
From 34.00€
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A-836339
Item number: TGM-T7375-100mg
Description: A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 receptor (Ki = 270 nM). It displays analgesic, anti-inflammatory, and anti-hyperalgesic effects in mice. Target: Cannabinoid Receptor. Smiles:...
| Application: | Synthetic cannabinoid, analgesic, antiinflammatory, antihyperalgesic |
| CAS | 959746-77-1 |
| MW: | 310.45 D |
From 39.00€
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LY2828360
Item number: TGM-T7316-100mg
Description: LY2828360 is a cannabinoid (CB) receptor 2 agonist (Ki = 40.3 nM). It selectively activates CB2 over CB1 in a GTPgammaS binding assay (EC50s = 20.1 and >100,000 nM, respectively). Target: Cannabinoid Receptor. Smiles: CN1CCN(CC1)c1nc(C)nc2n(C3CCOCC3)c(nc12)-c1ccccc1Cl. References: Lin X , Dhopeshwarkar...
| Application: | CB2 agonist |
| CAS | 1231220-79-3 |
| MW: | 426.94 D |
From 37.00€
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beta-Caryophyllene
Item number: TGM-T9114-500mg
Description: beta-Caryophyllene ((-)-(E)-Caryophyllene) acts as an CB2 receptor agonist. Target: Endogenous Metabolite, Cannabinoid Receptor. Smiles: [H][C@]12CC(C)(C)[C@]1([H])CC\C(C)=C/CCC2=C. References: Cheng Y, etal. beta-Caryophyllene ameliorates the Alzheimer-like phenotype in APP/PS1 Mice through CB2...
| Keywords: | (-)-beta-caryophyllene, (-)-trans-Caryophyllene, (-)-(E)-Caryophyllene |
| Application: | Antioxidant, antineuroinflammatory, antiproliferative, antinociceptive agent |
| CAS | 87-44-5 |
| MW: | 204.35 D |
41.00€
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PF-03550096
Item number: TGM-T84412-10mg
Description: PF-03550096, an orally active synthetic cannabinoid (CB), selectively binds to peripheral CB2 receptors with a Ki value of 7.9 nM, demonstrating analgesic activity [1]. Target: Others. Smiles: C(N[C@@H]([C@](C)(C)C)C(N)=O)(=O)N1C=2C(N(CCC(C)(C)O)C1=O)=CC=CC2
| Application: | Synthetic cannabinoid (CB2 receptor) |
| CAS | 910376-39-5 |
| MW: | 376.45 D |
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