365 products were found matching "K04277"!
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Human Cannabinoid receptor 1 Protein-VLP
Item number: KT-CNR-HM001-100UG
Recombinant Human Cannabinoid receptor 1 Protein-VLP is expressed from HEK293.It contains Met1-Leu472. The CB1 receptor also plays an important role in the gut-brain axis control of appetite and satiety. The combined effect of peripheral CB1 activation is to promote appetite, energy storage, and energy preservation...
| Keywords: | CB-R,CB R,CBR,CB1,CANN6,CANN6CB1R,Cannabinoid R1,CB1K5,CB1R,CB-RCB1cannabinoid receptor 1,central cannabinoid... |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 52.9 kD |
2,295.00€
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N-Arachidonoyl Dopamine
Item number: Cay90057-5
N-Arachidonoyl dopamine (NADA) is an arachidonoyl amino acid and cannabinoid (CB) receptor 1 agonist (Ki = 250 nM in rat brain membranes, which highly express CB1 receptors). It is selective for CB1 over CB2 receptors (Ki = 12,000 nM in rat spleen membranes, which highly express CB2 receptors). NADA induces...
| Keywords: | NADA, N-[2-(3,4-dihydroxyphenyl)ethyl]-5Z,8Z,11Z,14Z-eicosatetraenamide |
| Application: | CB1 agonist |
| CAS | 199875-69-9 |
| MW: | 439.6 D |
From 74.00€
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JWH 116
Item number: Cay13977-1
JWH 116 (Cay-13977) is a synthetic cannabinoid (CB) receptor ligand from the naphthoylindole family. It is the indole 2-ethyl derivative of the related compound JWH 018 (Cay-10900 and 13169) and has a Ki value of 52 nM for the CB1 receptor. This product is intended for research and forensic applications.Formal Name:...
| Keywords: | (2-ethyl-1-pentyl-1H-indol-3-yl)-1-naphthalenyl-methanone |
| Application: | Analytical reference standard, synthetic cannabinoid, CB1 receptor agonist |
| CAS | 619294-64-3 |
| MW: | 369.5 D |
From 61.00€
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AM251
Item number: Cay71670-10
AM251 is a cannabinoid 1 (CB1) receptor 1 antagonist. It binds to CB1 receptors in rat forebrain membrane preparations (Ki = 7.5 nM) and is selective over CB2 receptors in mouse spleen preparations (Ki = 2,290 nM) in radioligand binding assays. AM251 inhibits GTPgammaS binding induced by the CB receptor agonist CP...
| Keywords: | 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide |
| Application: | SR 141716A analog |
| CAS | 183232-66-8 |
| MW: | 555.2 D |
From 67.00€
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Otenabant hydrochloride
Item number: TGM-T1796-100mg
Description: Otenabant hydrochloride (Otenabant) (CP-945598) is a competitive, high affinity, selective antagonist of the CB1 receptor (Ki: 0.7 nM). Target: Cannabinoid Receptor. Smiles: Cl.CCNC1(CCN(CC1)c1ncnc2n(c(nc12)-c1ccccc1Cl)-c1ccc(Cl)cc1)C(N)=O. References: Griffith DA, et al. J Med Chem, 2009, 52(2), 234-237.
| Keywords: | Otenabant (CP-945598) HCl, CP 945598 Hydrochloride, Otenabant |
| Application: | Targets cannabinoid receptor 1 (CNR1) |
| CAS | 686347-12-6 |
| MW: | 546.88 D |
From 40.00€
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AM251
Item number: TGM-T1915-100mg
Description: AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors, also effective GPR55 agonist (EC50: 39 nM). Target: Cannabinoid Receptor, GPR. Smiles: CC1=C(N(N=C1C(NN2CCCCC2)=O)C3=C(Cl)C=C(Cl)C=C3)C4=CC=C(I)C=C4. References: Liao C, et al....
| Application: | SR 141716A analog |
| CAS | 183232-66-8 |
| MW: | 555.24 D |
From 43.00€
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Taranabant
Item number: TGM-T13080L-1mg
Description: Taranabant (MK-0364) is a selective and potent cannabinoid 1 (CB1) receptor inverse agonist used in the study of obesity and nicotine dependence. Target: Cannabinoid Receptor. Smiles: C[C@H](NC(=O)C(C)(C)Oc1ccc(cn1)C(F)(F)F)[C@@H](Cc1ccc(Cl)cc1)c1cccc(c1)C#N. References: Lin LS, et al. Discovery of...
| Keywords: | MK-0364 |
| Application: | Targets cannabinoid receptor 1 (CNR1) |
| CAS | 701977-09-5 |
| MW: | 515.96 D |
98.00€
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CB1 antagonist 2
Item number: TGM-T14881-100mg
Description: CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM. Target: Cannabinoid Receptor. Smiles: Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(N)=O. References: Song Li, et al. 4-methyl-diaryl -1H- pyrazole derivatives and their use as medicamentsFIELD.
| Keywords: | AM4113 |
| Application: | CNR1-selective neutral antagonist |
| CAS | 614726-85-1 |
| MW: | 380.66 D |
From 31.00€
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Rimonabant hydrochloride
Item number: TGM-T1519-100mg
Description: Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity. Target: Antibacterial, Cannabinoid Receptor. Smiles: n1(nc(c(c1c1ccc(cc1)Cl)C)C(=O)NN1CCCCC1)c1c(cc(cc1)Cl)Cl.Cl. References: Vivian JA, et al....
| Keywords: | SR 151716A, SR 141716A |
| Application: | CB1 inverse agonist |
| CAS | 158681-13-1 |
| MW: | 500.25 D |
From 40.00€
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Rimonabant
Item number: TGM-T1519L-100mg
Description: Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue of effect is a reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the...
| Keywords: | SR141716 |
| Application: | Targets cannabinoid receptor 1 (CNR1) |
| CAS | 168273-06-1 |
| MW: | 463.79 D |
From 42.00€
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LH 21
Item number: TGM-T21811-1mg
Description: LH-21 is a potent in vivo neutral cannabinoid CB1 receptor antagonist that reduces food intake and body weight gain in obese Zucker rats, resulting in a dose-dependent inhibition of feeding [1]. Target: Others. Smiles: ClC1=C(N2C(=NC(CCCCCC)=N2)C3=CC=C(Cl)C=C3)C=CC(Cl)=C1
| Application: | CB1 antagonist |
| CAS | 611207-11-5 |
| MW: | 408.75 D |
From 148.00€
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GAT211
Item number: TGM-T27405-100mg
Description: GAT211 (AZ-4) is a selective and potent cannabinoid 1 receptor (CB1R) orthosteric modulator (PAM) with high affinity for cAMP and beta-arrestin2.GAT211 has IOP-lowering and antipsychotic effects and can be used in the study of epilepsy. Target: Cannabinoid Receptor, cAMP, Arrestin. Smiles:...
| Keywords: | AZ 4, GAT-211, AZ4, AZ-4, GAT 211 |
| Application: | Cannabinoid receptor 1 agonist / positive allosteric modulator (PAM) |
| CAS | 102704-40-5 |
| MW: | 342.39 D |
From 31.00€
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