35 products were found matching "K04270"!
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BPTU
Item number: TGM-T4132-100mg
Description: BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 µM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists. Antithrombotic, reduces...
| Keywords: | BMS-646786 |
| Application: | Allosteric P2Y1 receptor antagonist |
| CAS | 870544-59-5 |
| MW: | 445.43 D |
From 33.00€
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2-Chloroadenosine 5-triphosphate sodium
Item number: TGM-T84928-10mg
Description: 2-Chloroadenosine 5-triphosphate (2-chloro ATP), an analog of ATP and adenine nucleotide, functions as an antagonist of the purinergic P2Y1 receptor, inhibiting ADP-induced intracellular calcium mobilization in Jurkat cells with a Ki value of 2.3 µM. Additionally, 2-chloro ATP acts as an agonist of...
| Keywords: | 2-chloro ATP |
| Application: | Adenine nucleotide, ATP analog, P2Y1 receptor antagonist |
| CAS | 301334-89-4 |
| MW: | 629.55 D |
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P2Y1 Protein, Human, Recombinant (His)
Item number: TGM-TMPH-01822-100ug
Description: Receptor for extracellular adenine nucleotides such as ADP. In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation. P2Y1 Protein, Human, Recombinant (His) is expressed in E. coli...
| Keywords: | Purinergic receptor, P2RY1, ADP receptor, P2Y purinoceptor 1 |
| MW: | 12.4 kD |
From 281.00€
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P2Y purinoceptor 1 (P2ry1), mouse, recombinant
Item number: CSB-CF017326MO.100
Organism: Mus musculus (Mouse). Source: in vitro E.coli expression system. Expression Region: 1-373aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MTEVPWSVVP NGTDAAFLAG LGSLWGNSTV ASTAAVSSSF QCALTKTGFQ FYYLPAVYIL VFIIGFLGNS VAIWMFVFHM KPWSGISVYM FNLALADFLY VLTLPALIFY...
| Keywords: | P2Y1, P2ry1, ADP receptor, P2Y purinoceptor 1, Purinergic receptor, Recombinant Mouse P2Y purinoceptor 1 (P2ry1) |
| Application: | Activity not tested |
| Expressed in: | E.coli in vitro |
| Origin: | mouse |
| MW: | 48.3 kD |
From 1,458.00€
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P2Y purinoceptor 1 (P2RY1), partial, human, recombinant
Item number: CSB-EP017326HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 326-373aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: LAGDTFRRRL SRATRKASRR SEANLQSKSE DMTLNILPEF KQNGDTSL. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a....
| Keywords: | P2Y1, P2RY1, ADP receptor, P2Y purinoceptor 1, Purinergic receptor, Recombinant Human P2Y purinoceptor 1 (P2RY1), partial |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 12.4 kD |
From 292.00€
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Anti-P2RY1
Item number: CSB-PA548912.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: P2RY1. Antigen Species: Human
| Keywords: | Anti-P2Y1, Anti-P2RY1, Anti-ADP receptor, Anti-P2Y purinoceptor 1, Anti-Purinergic receptor, ATP receptor antibody, P2... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-P2RY1
Item number: CSB-PA929730.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: P2RY1. Antigen Species: Human
| Keywords: | Anti-P2Y1, Anti-P2RY1, Anti-ADP receptor, Anti-P2Y purinoceptor 1, Anti-Purinergic receptor, ATP receptor antibody, P2... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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MRS2179 (ammonium salt hydrate)
Item number: Cay10011450-10
MRS2179 is a competitive purinergic P2Y1 receptor antagonist (Kb = 102 nM). It is selective for P2Y1 over P2Y2, P2Y4, P2Y6, P2Y12, and P2Y13, as well as P2X1-4, receptors at 10 µM. MRS2179 reduces phospholipase C (PLC) activity induced by the P2Y receptor agonist 2-methylthioadenosine diphosphate (2-MeSADP,...
| Keywords: | 2'-deoxy-N-methyl-3'-adenylic acid, 5'-(dihydrogen phosphate), ammonium salt, hydrate |
| Application: | Competitive P2Y1 receptor antagonist |
| MW: | 425.2 D |
From 55.00€
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BPTU
Item number: Cay29444-10
BPTU is an allosteric antagonist of the purinergic P2Y1 receptor (Ki = 6 nM for the human receptor). BPTU is selective for P2Y1 over P2Y2, P2Y6, P2Y11, P2Y12, and P2Y14 receptors (Kis = >3,500 nM). It inhibits platelet aggregation in human platelet-rich plasma (hPRP, IC50 = 2.1 µM). BPTU reduces thrombus weight by...
| Keywords: | N-[2-[2-(1,1-dimethylethyl)phenoxy]-3-pyridinyl]-N'-[4-(trifluoromethoxy)phenyl]-urea |
| Application: | Allosteric P2Y1 receptor antagonist |
| CAS | 870544-59-5 |
| MW: | 445.4 D |
From 44.00€
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Anti-P2RY1 / P2Y1
Item number: ARG57509.100
Protein function: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [The UniProt Consortium]
| Keywords: | Anti-P2Y1, Anti-P2RY1, Anti-ATP receptor, Anti-P2Y purinoceptor 1, Anti-Purinergic receptor |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
616.00€
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Anti-P2RY1
Item number: E-AB-12606.120
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In...
| Keywords: | Anti-P2Y1, Anti-P2RY1, Anti-ATP receptor, Anti-P2Y purinoceptor 1, Anti-Purinergic receptor, P2RY1 Polyclonal Antibody |
| Application: | IHC, ELISA |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 89.00€
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Human P2RY1(PURINERGIC RECEPTOR P2Y, G PROTEIN) ELISA Kit
Item number: G-HUFI03143.96
Protein function: Receptor for extracellular adenine nucleotides such as ADP (PubMed:9442040, PubMed:9038354, PubMed:25822790). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation...
| Keywords: | P2Y1, P2RY1, ADP receptor, P2Y purinoceptor 1, Purinergic receptor |
641.00€
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