32 products were found matching "K04263"!
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Iloprost
Item number: LKT-I458579.1
Iloprost is a synthetic analogue of prostacyclin. This product includes a mixture of 4R and 4S diastereomers. SMILES: CC#CCC(C)C(C=CC1C(CC2C1CC(=CCCCC(=O)O)C2)O)O
| Keywords: | Cilaprost, Ventavis, Endoprost, Ilomedin, Iloprostum, UNII-JED5K35YGL, ZK-36374, JED5K35YGL,... |
| Application: | Prostacyclin analog |
| CAS | 78919-13-8 |
| MW: | 360.5 D |
From 313.00€
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Epoprostenol sodium
Item number: TGM-T15238-10mg
Description: Epoprostenol sodium is a potent inhibitor of platelet aggregation used in pulmonary hypertension and transplantation. Target: Others. Smiles: [Na+].CCCCCC(O)C=CC1C(O)CC2OC(CC12)=CCCCC([O-])=O. References: Provencher S, et al.Quality of life, safety and efficacy profile of thermostable flolan in...
| Keywords: | Prostacyclin sodium salt, Prostaglandin I2 sodium salt, Flolan |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 61849-14-7 |
| MW: | 375.461 D |
From 181.00€
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Iloprost
Item number: TGM-T15560-1mg
Description: Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost commonly employed in the treatment of peripheral vascular disease and also indicated in the treatment of patients affected by systemic sclerosis (SSc) in the presence of severe Raynaud's phenomenon (RP). Target: Others. Smiles:...
| Keywords: | Ciloprost, ZK 36374 |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 78919-13-8 |
| MW: | 360.49 D |
From 170.00€
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Epoprostenol
Item number: TGM-T20778-25mg
Description: Epoprostenol, a prostaglandin, is a powerful vasodilator. It inhibits platelet aggregation. Target: Others. Smiles: C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@]2([C@@](O/C(=C\CCCC(O)=O)/C2)(C[C@H]1O)[H])[H]. References: Ahmad KA, Banales J, Henderson CL, Ramos SE, Brandt KM, Powers GC. Intravenous epoprostenol...
| Keywords: | U 53217, U-53,217, U 53,217 |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 35121-78-9 |
| MW: | 352.47 D |
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Selexipag
Item number: TGM-T3216-10mg
Description: Selexipag (ACT-293987)(NS-304) is prostacyclin receptor agonist that causes vasodilation in pulmonary vasculature and is used in the therapy of pulmonary arterial hypertension (PAH). Target: Others, Prostaglandin Receptor. Smiles: N(CCCCOCC(NS(C)(=O)=O)=O)(C(C)C)C=1N=C(C(=NC1)C2=CC=CC=C2)C3=CC=CC=C3....
| Keywords: | Uptravi, NS-304, ACT-293987 |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 475086-01-2 |
| MW: | 496.62 D |
From 42.00€
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Beraprost
Item number: TGM-T30426-25mg
Description: Beraprost is a stable prostacyclin analog. Target: Others. Smiles: CC#CCC(C)C(O)C=CC1C(O)CC2Oc3c(cccc3CCCC(O)=O)C12 , w:9.9, . References: Zhang P, Xu L, Guan H, Liu L, Liu J, Huang Z, Cao X, Liao Z, Xiao H, Li Y. Beraprost sodium, a prostacyclin analogue, reduces fructose-induced hepatocellular...
| Keywords: | ML-1229, MDL-201229, MDL 201229, ML 1229 |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 88430-50-6 |
| MW: | 398.499 D |
1,520.00€
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Ciprostene (calcium salt)
Item number: TGM-T36732-10mg
Description: Ciprostene is the 9beta-methyl analog of carbaprostacyclin and a stable analog of PGI2. Ciprostene exhibits biological activity similar to PGI2, but is 30-fold less potent. In patas monkeys, ciprostene induces hypotension and causes tachycardia when administered at a dose of 0.16 µg/kg/min. In addition,...
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 81703-55-1 |
| MW: | 771.146 D |
From 380.00€
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Ralinepag
Item number: TGM-T4635-100mg
Description: Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively. Target: Prostaglandin Receptor, Others. Smiles:...
| Keywords: | APD811 |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 1187856-49-0 |
| MW: | 431.91 D |
From 55.00€
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Treprostinil
Item number: TGM-T5150-100mg
Description: Treprostinil (Orenitram) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM). Target: Prostaglandin Receptor. Smiles: CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@@H]2Cc3c(C[C@H]12)cccc3OCC(O)=O. References: Whittle BJ, et al. Binding and activity of the prostacyclin receptor (IP) agonists, treprostinil and...
| Keywords: | Orenitram, LRX-15, Remodulin |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 81846-19-7 |
| MW: | 390.51 D |
From 40.00€
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Treprostinil Sodium
Item number: TGM-T5171-10mg
Description: Treprostinil Sodium (UT-15) is a potent DP1, IP and EP2 agonist (EC50: 0.6/1.9/6.2 nM). Target: c-RET, Prostaglandin Receptor, VEGFR. Smiles: [Na+].CCCCC[C@H](O)CC[C@H]1[C@H](O)C[C@@H]2Cc3c(C[C@H]12)cccc3OCC([O-])=O. References: Whittle BJ, et al. Binding and activity of the prostacyclin receptor (IP)...
| Keywords: | UT-15 |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 289480-64-4 |
| MW: | 412.5 D |
From 46.00€
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Clinprost
Item number: TGM-T68433-100mg
Description: Clinprost is a Vasodilator (peripheral), Platelet aggregation inhibitor, and Prostaglandin I2 receptor agonist. Target: Others. Smiles: C(=C/[C@H](CCCCC)O)\[C@@H]1[C@@]2([C@@](C=C(CCCCC(OC)=O)C2)(C[C@H]1O)[H])[H]
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 88931-51-5 |
| MW: | 364.52 D |
From 1,520.00€
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Treprostinil diethanolamine
Item number: TGM-T63349-100mg
Description: Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1, and IP, with values of 3.6, 4.4, and 32.1 nM for EP2, DP1, and IP, respectively, and 212, 826, 2505, and 4680 nM for EP1, EP4, EP3, and FPKi, respectively. Treprostinil diethanolamine contributes to the upregulation of cAMP,...
| Keywords: | UT-15C |
| Application: | Targets prostacyclin receptor (PTGIR) |
| CAS | 830354-48-8 |
| MW: | 495.65 D |
From 67.00€
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