58 products were found matching "K04259"!
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Omidenepag
Item number: TGM-T16389-1mg
Description: Omidenepag (UR-7276) is a selective and potent prostaglandin E2 receptor 2 (EP2) agonist and a novel topical ocular hypotensive agent.Omidenepag is used in the study of glaucoma and hypertension. Target: Prostaglandin Receptor. Smiles: OC(=O)CNc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)n1....
| Keywords: | UR-7276 |
| Application: | Targets prostaglandin E receptor 2 (PTGER2) |
| CAS | 1187451-41-7 |
| MW: | 478.52 D |
68.00€
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Taprenepag isopropyl
Item number: TGM-T16988-2mg
Description: Taprenepag isopropyl is a highly selective agonist of the EP2 receptor. Target: Prostaglandin Receptor. Smiles: CC(C)OC(=O)COc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)c1. References: Yanochko GM, et al. Investigation of ocular events associated with taprenepag isopropyl, a topical EP2 agonist in...
| Keywords: | PF-04217329 |
| Application: | Targets prostaglandin E receptor 2 (PTGER2) |
| CAS | 1005549-94-9 |
| MW: | 520.6 D |
48.00€
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TG6-129
Item number: TGM-T28958-100mg
Description: TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 reduces the expression of COX-2, IL-1beta, IL-6, IL-12, IL-23 and TNF-alpha induced by the EP2-selective agonist butaprost in P388D1 macrophages....
| Keywords: | TG6 129 |
| Application: | EP2 receptor antagonist |
| CAS | 1164464-14-5 |
| MW: | 491.58 D |
From 120.00€
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PF-04418948
Item number: TGM-T3306-100mg
Description: PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors, exhibits <30% binding at a diverse panel of GPCRs and ion channels at a concentration of 10 µM. Inhibits PGE2-induced...
| Keywords: | PF 04418948, PF04418948 |
| Application: | EP2 receptor antagonist |
| CAS | 1078166-57-0 |
| MW: | 409.41 D |
From 40.00€
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TG4-155
Item number: TGM-T5482-100mg
Description: TG4-155 is a brain penetrant EP2 antagonist (KB = 2.4 nM) that is over 1000-fold less effective at EP4 (KB = 11.4 µM) and a panel of other receptors and channels. Target: Prostaglandin Receptor. Smiles: COc1cc(\C=C\C(=O)NCCn2c(C)cc3ccccc23)cc(OC)c1OC. References: Jiang J , Ganesh T , Du Y , et al. Small...
| Application: | Brain penetrant EP2 antagonist |
| CAS | 1164462-05-8 |
| MW: | 394.46 D |
From 31.00€
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Arbaprostil
Item number: TGM-T71801-1mg
Description: Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inhibitor of pancreatic function and can inhibit the growth of experimental tumors....
| Application: | Targets prostaglandin E receptor 2 (PTGER2) |
| CAS | 55028-70-1 |
| MW: | 366.49 D |
385.00€
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TG11-77 hydrochloride
Item number: TGM-T85023-10mg
Description: TG11-77 hydrochloride is a potent, selective, and water-soluble EP2 receptor antagonist that is brain-permeable, demonstrating a KB value of 9.7 nM. Target: Others. Smiles: C(CNC(=O)C=1C=NC(NC2=CC(C)=CC(C)=N2)=NC1)C=3C=4C(NC3C)=CC=CC4.Cl
| Application: | Prostanoid EP2 receptor antagonist |
| CAS | 2550393-38-7 |
| MW: | 436.94 D |
Please request pricing for this article.
Prostaglandin E2 receptor EP2 subtype (Ptger2), partial,...
Item number: CSB-EP730772MO1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 324-362aa. Protein Length: Partial. Tag Info: Tag-Free. Target Protein Sequence: RLMRSVLCCR TSLRTQEAQQ TSCSTQSSAS KQTDLCGQL. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: Not test. Biological Activity: n/a. Form: Liquid or...
| Keywords: | Ptger2, Ptgerep2, Prostanoid EP2 receptor, PGE receptor EP2 subtype, PGE2 receptor EP2 subtype, Prostaglandin E2 receptor... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 4.3 kD |
From 496.00€
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Anti-PTGER2
Item number: CSB-PA040059.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-PTGER2, Anti-Prostanoid EP2 receptor, Anti-PGE receptor EP2 subtype, Anti-PGE2 receptor EP2 subtype,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 106.00€
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Anti-PTGER2 Recombinant Monoclonal, clone 8D8
Item number: CSB-RA585843A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: PTGER2. Antigen Species: Human
| Keywords: | Anti-PTGER2, Anti-Prostanoid EP2 receptor, Anti-PGE receptor EP2 subtype, Anti-PGE2 receptor EP2 subtype,... |
| Application: | ELISA, WB, IHC, FC |
| Host: | Rabbit |
| Species reactivity: | human |
From 201.00€
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Anti-PTGER2
Item number: CSB-PA189021.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PTGER2. Antigen Species: Human
| Keywords: | Anti-PTGER2, Anti-Prostanoid EP2 receptor, Anti-PGE receptor EP2 subtype, Anti-PGE2 receptor EP2 subtype,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 163.00€
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Anti-PTGER2
Item number: CSB-PA546249.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PTGER2. Antigen Species: Human
| Keywords: | Anti-PTGER2, Anti-Prostanoid EP2 receptor, Anti-PGE receptor EP2 subtype, Anti-PGE2 receptor EP2 subtype,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 163.00€
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