36 products were found matching "K04234"!
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PAR2 (1-6) amide (human) (trifluoroacetate salt)
Item number: TGM-T35955-10mg
Description: PAR2 (1-6) amide is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR2 and residues 37-42 of the full-length sequence.1It binds to NCTC 2544 cells expressing human PAR2 (Ki= 9.64 µM in a...
| Keywords: | PAR2 (1-6) amide (human) (trifluoroacetate salt) |
| Application: | PAR2 peptide agonist |
| CAS | 2379569-17-0 |
| MW: | 728.812 D |
From 151.00€
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PAR2 (1-6) (mouse, rat)
Item number: TGM-T36531-10mg
Description: PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6)...
| Keywords: | PAR2 (1-6) (mouse, rat) |
| Application: | Synthetic peptide PAR2 agonist |
| CAS | 164081-25-8 |
| MW: | 657.814 D |
From 108.00€
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I-191
Item number: TGM-T7137-100mg
Description: I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells. Target: Protease-activated Receptor. Smiles: CC(C)(C)c1cc(nn2cc(nc12)C(=O)N1CCNC(=O)C1(C)C)-c1ccc(F)cc1. References: Jiang Y , Yau M K , Lim J , et al. A potent antagonist...
| Application: | PAR2 antagonist |
| CAS | 1690172-25-8 |
| MW: | 423.48 D |
From 80.00€
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AZ3451
Item number: TGM-TQ0012-100mg
Description: AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM). Target: Protease-activated Receptor. Smiles: C[C@@H](C1CCCCC1)n1c(nc2cc(ccc12)C(=O)Nc1ccc(cc1)C#N)-c1cc2OCOc2cc1Br. References: Cheng RKY, et al. Structural insight into allosteric modulation of protease-activated...
| Application: | Allosteric PAR2 antagonist |
| CAS | 2100284-59-9 |
| MW: | 571.46 D |
From 38.00€
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FSLLRY-NH2
Item number: TGM-TP1904-10mg
Description: Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch. References: McLarty et...
| Application: | PAR2 antagonist |
| CAS | 245329-02-6 |
| MW: | 796.97 D |
From 218.00€
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Human F2RL1 Protein, hFc Tag
Item number: DIM-PME101118.10
Recombinant human F2RL1 protein with C-terminal human Fc tag. F2RL1(Ser37-Gly71) hFc(Glu99-Ala330), Protein function: Receptor for trypsin and trypsin-like enzymes coupled to G proteins (PubMed:28445455). Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC),...
| Keywords: | GPR11, PAR2 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 29.7 kD |
From 144.00€
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F2RL1 (human) full length protein-synthetic nanodisc
Item number: DIM-FLP100036.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Keywords: | GPR11, F2RL1, GPR11, PAR2, Human F2RL1 full length protein-synthetic nanodisc |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 44.1 kD |
From 1,260.00€
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SLIGRL-NH2 (trifluoroacetate salt)
Item number: Cay16723-1
Proteinase-activated receptor 2 (PAR2) is a G protein-coupled receptor that is cleaved by serine proteases, resulting in self-activation of the receptor by a tethered ligand. The ligand corresponds to residues 39-44 (SLIGRL in mouse PAR-2). SLIGRL-NH2 is a recombinant peptide that activates PAR2 (EC50 = ~5 µM),...
| Keywords: | L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-Leucinamide, trifluoroacetate salt |
| Application: | PAR-2 activator |
| MW: | 656.8 D |
From 50.00€
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I-191
Item number: Cay37553-100
I-191 is an antagonist of proteinase-activated receptor 2 (PAR2, IC50 = 72.4 nM in HT-29 cells expressing the human receptor). It inhibits trypsin-induced calcium release in HT-29 cells (IC50 = 200 nM for the human receptor). I-191 (0.1, 1, and 10 µM) reduces the migration of HT-29 cells in a scratch assay. It...
| Keywords: | 4-[[8-(1,1-dimethylethyl)-6-(4-fluorophenyl)imidazo[1,2-b]pyridazin-2-yl]carbonyl]-3,3-dimethyl-2-piperazinone |
| Application: | PAR2 antagonist |
| CAS | 1690172-25-8 |
| MW: | 423.5 D |
From 204.00€
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Rat PAR2 (Protease Activated Receptor 2) ELISA Kit
Item number: ELK-ELK1638.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PAR2. Next,...
| Keywords: | Par2, PAR-2, F2rl1, Thrombin receptor-like 1, Proteinase-activated receptor 2, Coagulation factor II receptor-like 1 |
| Application: | ELISA |
| Species reactivity: | rat |
From 365.00€
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Mouse PAR2 (Protease Activated Receptor 2) ELISA Kit
Item number: ELK-ELK1639.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PAR2. Next,...
| Keywords: | PAR-2, F2rl1, Gpcr11, Thrombin receptor-like 1, G-protein coupled receptor 11, Proteinase-activated receptor 2,... |
| Application: | ELISA |
| Species reactivity: | mouse |
From 365.00€
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Human PAR2 (Protease Activated Receptor 2) ELISA Kit
Item number: ELK-ELK2416.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PAR2. Next,...
| Keywords: | GPR11, F2RL1 |
| Application: | ELISA |
| Species reactivity: | human |
From 365.00€
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