30 products were found matching "K04199"!

Dersimelagon is an agonist of melanocortin receptor 1 (MC1R). It selectively induces cAMP accumulation in HEK293 cells expressing human MC1R (EC50 = 8.16 nM) over HEK293 cells expressing human MC2R (EC50 = >10,000 nM) but also induces cAMP accumulation in HEK293 cells expressing human MC4R (EC50 = 79.6 nM)....

[Nle4,D-Phe7]-alpha-Melanocyte-stimulating hormone ([Nle4,D-Phe7]-alpha-MSH) is a peptide agonist of melanocortin receptor 1 (MC1R). It induces cAMP accumulation in mouse L-cells expressing human MC1R (EC50 = 0.5 nM). It also induces tyrosinase activity in mouse melanoma cells. In vivo, [Nle4,D-Phe7]-alpha-MSH (1.8...

MSG606 is a peptide antagonist of melanocortin receptor 1 (MC1R, IC50 = 17 nM for the human receptor) and a derivative of gamma-melanocyte-stimulating hormone (gamma-MSH). It selectively binds to MC1R over MC3R and MC5R (IC50s = 3,900 and 1,000 nM, respectively, for the human receptors), as well as MC4R at 10 µM....

hMC1R agonist 1 is a peptide agonist of melanocortin receptor 1 (MC1R) and a derivative of melanotan-II (Cay-27316). It selectively induces cAMP production in HEK293 cells expressing recombinant human MC1R over those expressing recombinant human MC3R, MC4R, or MC5R (EC50s = 3, 902, 915, and >1,000 nM,...

Description: Afamelanotide acetate is a synthetic alpha-melanocyte stimulating hormone analogue and first-in-class melanocortin-1 receptor agonist, used to for Erythropoietic Protoporphyria. Target: Melanocortin Receptor. Smiles:...

Description: Bremelanotide Acetate (PT-141 Acetate) is an agonist of melanocortin receptor (MCR) . Target: Melanocortin Receptor. Smiles:...

Description: Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an alpha-melanocyte-stimulating hormone (alpha-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as an adjunct to tanning Melanotan I has been used for the prevention of...

Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1-317aa. Protein Length: Full Length. Tag Info: C-terminal 10xHis-tagged(This tag can be tested only under denaturing conditions). Target Protein Sequence: MAVQGSQRRL LGSLNSTPTA IPQLGLAANQ TGARCLEVSI SDGLFLSLGL VSLVENALVV ATIAKNRNLH...

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MC1R. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MC1R. Antigen Species: Human

This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are...