51 products were found matching "K04198"!
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ACT-373898
Item number: TGM-T35623-10mg
Description: ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ETA) and ETBdual antagonist macitentan .1. Target: Others. Smiles: CCCNS(=O)(=O)Nc1ncnc(OCC(O)=O)c1-c1ccc(Br)cc1. References: Dingemanse, J., Sidharta, P.N., Maddrey, W.C., et al.Efficacy, safety and clinical pharmacology of macitentan...
| Application: | Macitentan metabolite |
| CAS | 1433875-14-9 |
| MW: | 445.29 D |
From 93.00€
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BE-24566B
Item number: TGM-T38167-1mg
Description: BE-24566B is a polyketide fungal metabolite originally isolated fromS. violaceusniger.1It is active againstB. subtilis,B. cereus,S. aureus,M. luteus,E. faecalis, andS. thermophilus(MICs = 1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 µg/ml, respectively). BE-24566B is an endothelin (ET) receptor antagonist...
| Application: | Fungal metabolite, ET receptor antagonist |
| CAS | 149466-04-6 |
| MW: | 460.482 D |
839.00€
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Endothelin B Receptor Protein, Human, Recombinant (His)
Item number: TGM-TMPY-00181-100ug
Description: Endothelin B Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.5 kDa and the accession number is P24530-1.
| Keywords: | ETBR, ET-B, ET-BR, ETB, endothelin receptor type B, HSCR2, ABCDS, HSCR, WS4A, ETRB |
| MW: | 9.5 kD |
699.00€
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Endothelin B Receptor Protein, Human, Recombinant (mFc)
Item number: TGM-TMPY-03860-100ug
Description: Endothelin B Receptor Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34.4 kDa and the accession number is P24530-1.
| Keywords: | ETBR, ET-BR, ETRB, ET-B, ETB, endothelin receptor type B, HSCR, WS4A, HSCR2, ABCDS |
| MW: | 34.4 kD |
699.00€
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IRL 2500
Item number: TGM-T15596-100mg
Description: IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor. Target: Endothelin Receptor. Smiles: CN([C@H](Cc1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O)C(=O)c1cc(C)cc(C)c1. References: Balwierczak JL, et al....
| Application: | Endothelin receptor type B (ETBR) antagonist |
| CAS | 169545-27-1 |
| MW: | 573.68 D |
From 45.00€
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Endothelin receptor type B (EDNRB) (Active), human,...
Item number: CSB-CF007404HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 27-442aa. Protein Length: Full Length. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: EERGFPPDRA TPLLQTAEIM TPPTKTLWPK GSNASLARSL APAEVPKGDR TAGSPPRTIS PPPCQGPIEI KETFKYINTV VSCLVFVLGI IGNSTLLRII YKNKCMRNGP...
| Keywords: | ETRB, ET-B, ET-BR, Endothelin receptor type B, Endothelin receptor non-selective type, Recombinant Human Endothelin... |
| Application: | Active protein |
| Expressed in: | E.coli in vitro |
| Origin: | human |
| MW: | 48.8 kD |
From 943.00€
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Human EDNRB Protein, hFc Tag
Item number: DIM-PME101525.10
Recombinant human EDNRB Protein with C-terminal human Fc tag. EDNRB(Glu27-Lys101) hFc(Glu99-Ala330), Protein function: Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. [The UniProt Consortium]
| Keywords: | ETB, ET-B, ETB1, ETBR, ETRB, HSCR, WS4A, ABCDS, ET-BR, HSCR2 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 34.2 kD |
From 129.00€
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Anti-EDNRB
Item number: CSB-PA093669.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: EDNRB. Antigen Species: Human
| Keywords: | Anti-ETRB, Anti-ET-B, Anti-ET-BR, Anti-Endothelin receptor type B, Anti-Endothelin receptor non-selective type, ABCDS... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Anti-EDNRB
Item number: CSB-PA460645.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-ETRB, Anti-ET-B, Anti-ET-BR, Anti-Endothelin receptor type B, Anti-Endothelin receptor non-selective type, ABCDS... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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Anti-EDNRB
Item number: CSB-PA708179.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen....
| Keywords: | Anti-ETRB, Anti-ET-B, Anti-ET-BR, Anti-Endothelin receptor type B, Anti-Endothelin receptor non-selective type, ABCDS... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
126.00€
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Anti-EDNRB
Item number: CSB-PA937611.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: EDNRB. Antigen Species: Human
| Keywords: | Anti-ETRB, Anti-ET-B, Anti-ET-BR, Anti-Endothelin receptor type B, Anti-Endothelin receptor non-selective type, ABCDS... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Macitentan
Item number: Cay23304-50
Macitentan is a dual antagonist of the endothelin (ET) receptors type A and B (IC50s = 0.5 and 391 nM in a radioligand binding assay using recombinant ETA and ETB, respectively). Macitentan inhibits intracellular Ca2+ increases induced by the endothelin isoform ET-1 in human pulmonary arterial smooth muscle cells...
| Keywords: | ACT-064992, N-[5-(4-bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy]-4-pyrimidinyl]-N'-propyl-sulfamide |
| Application: | Dual EDNRA / EDNRB antagonist |
| CAS | 441798-33-0 |
| MW: | 588.3 D |
From 54.00€
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