183 products were found matching "K04189"!
No results were found for the filter!
Plerixafor (hydrochloride hydrate)
Item number: Cay10011332-1
The alpha-chemokine receptor, CXCR4, on CD4+ T-cells is used by CXCR4-selective HIV forms as a gateway for T-cell infection. In mammalian cell signaling, CXCR4 activation promotes the homing of hematopoietic stem cells, chemotaxis and quiescence of lymphocytes, and growth and metastasis of certain cancer cell types....
| Keywords: | AMD 3100, JM 3100, SID 791, 1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzene, octahydrochloride |
| Application: | CXCR4 binding antagonist |
| MW: | 794.5 D |
From 25.00€
*
WZ811
Item number: TGM-T1739-100mg
Description: WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM). Target: CXCR. Smiles: C(Nc1ccccn1)c1ccc(CNc2ccccn2)cc1. References: Zhan W, et al. J Med Chem, 2007, 50(23), 5655-5664.
| Application: | CXCR4 antagonist |
| CAS | 55778-02-4 |
| MW: | 290.36 D |
From 30.00€
*
Plerixafor
Item number: TGM-T1776-100mg
Description: Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4. Target: CXCR, HIV Protease, Virus Protease. Smiles: C(N1CCCNCCNCCC NCC1)c1ccc(CN2CCCNCCNCCCNCC2)cc1. References: Zabel BA, et al. J Immunol. 2009,...
| Keywords: | AMD 3100, JM3100, AMD-3329 |
| Application: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 110078-46-1 |
| MW: | 502.78 D |
From 42.00€
*
NUCC-390 dihydrochloride
Item number: TGM-T63004-1mg
Description: NUCC-390 dihydrochloride, a novel and selective CXCR4 receptor agonist, effectively induces the internalization of CXCR4 receptors and acts antagonistically to AMD3100 [1]. This small-molecule compound has demonstrated the ability to facilitate functional nerve recovery following neurodegeneration in...
| Application: | CXCR4 agonist |
| CAS | 2749281-71-6 |
| MW: | 468.46 D |
From 198.00€
*
Motixafortide
Item number: TGM-T14665-25mg
Description: Motixafortide (BKT140 4-fluorobenzoyl) is a CXCR4 antagonist with an IC50 of 1 nM. Target: CXCR. Smiles:...
| Keywords: | BL-8040, BKT140 (4-fluorobenzoyl), TF14016 |
| Application: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 664334-36-5 |
| MW: | 2159.52 D |
From 745.00€
*
MSX-122
Item number: TGM-T3992-100mg
Description: MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM). Target: CXCR. Smiles: C(Nc1ncccn1)c1ccc(CNc2ncccn2)cc1. References: Liang Z, et al. Development of a unique small molecule modulator of CXCR4. PLoS One. 2012,7(4):e34038.
| Keywords: | MSX122, MSX 122 |
| Application: | CXCR4 partial antagonist |
| CAS | 897657-95-3 |
| MW: | 292.34 D |
From 58.00€
*
CXCR4 Protein, Human, Recombinant (hFc)
Item number: TGM-TMPJ-01037-10ug
Description: C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor is one of several chemokine receptors that HIV isolates can use to infect CD4+ T...
| Keywords: | CXCR4,CD184,Fusin,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM |
| MW: | 45 kD |
From 139.00€
*
CXCR4 Protein, Human, Recombinant
Item number: TGM-TMPY-06553-100ug
Description: CXCR4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.75 kDa and the accession number is P61073-1.
| Keywords: | FB22, NPYR, LAP3, LAP-3, WHIM, NPY3R, LCR1, CD184, LESTR, WHIMS, HM89, HSY3RR, NPYRL, D2S201E, chemokine (C-X-C motif)... |
| MW: | 39.75 kD |
From 839.00€
*
Mavorixafor
Item number: TGM-TQ0174-100mg
Description: Mavorixafor (AMD-070) is an effective and selective antagonist of CXCR4, with an IC50 value of 13 nM against CXCR4 125I-SDF binding. Mavorixafor inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells (IC50 = 1 nM) and PBMCs (IC50 = 9 nM). Target: CXCR. Smiles:...
| Keywords: | AMD-070 |
| Application: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 558447-26-0 |
| MW: | 349.47 D |
From 63.00€
*
Balixafortide
Item number: TGM-TP2141L-100mg
Description: Balixafortide (POL6326) is a potent, selective, and well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM, and also acts as a potent hematopoietic stem and progenitor cell (HSPC) mobilizing agent. It demonstrates anti-cancer effects[1][2], blocks beta-arrestin recruitment and calcium flux with...
| Keywords: | POL6326 |
| Application: | Targets C-X-C chemokine receptor type 4 (CXCR4, CD184) |
| CAS | 1051366-32-5 |
| MW: | 1864.14 D |
Please request pricing for this article.
Anti-CXCR4
Item number: ARG67142.100
Protein function: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:10452968, PubMed:28978524, PubMed:18799424, PubMed:24912431). Involved in the AKT signaling cascade (PubMed:24912431). Plays a role in...
| Keywords: | Anti-FB22, Anti-HM89, Anti-LCR1, Anti-FB22, Anti-HM89, Anti-LCR1, Anti-CXCR4, Anti-Fusin, Anti-LAP-3, Anti-NPYRL,... |
| Application: | IHC (paraffin), WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
616.00€
*
Anti-CXCR4
Item number: CSB-PA002588.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-FB22, Anti-LCR1, Anti-HM89, Anti-CD184, Anti-LESTR, Anti-NPYRL, Anti-Fusin, Anti-LAP-3, Anti-CXCR4, Anti-CXCR-4,... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 126.00€
*