37 products were found matching "K04174"!
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ML221
Item number: TGM-T4390-100mg
Description: ML221 is a potent apelin /APJ functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 µM in the cAMP assay, and 1.75 µM in the beta-arrestin assay, and EC80 of 10 nM in both assays. Target: Apelin receptor, Arrestin. Smiles:...
| Application: | Apelin receptor (APJ) antagonist |
| CAS | 877636-42-5 |
| MW: | 385.35 D |
From 49.00€
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Apelin-36(human)
Item number: TGM-TP2093-1mg
Description: Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61). Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into...
| Keywords: | Apelin-36 (human) |
| Application: | APJ agonist |
| CAS | 252642-12-9 |
| MW: | 4195.87 D |
1,482.00€
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(Glp1)-Apelin-13 (trifluoroacetate salt)
Item number: Cay15590-1
The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids: apelin-36 (Cay-13524), apelin-17, and apelin-13 (Cay-13523), respectively. Apelin-13 is an endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50...
| Keywords: | (pGlu1)Apelin-13, (Pyr1)Apelin-13, Pyr-Apelin-13,... |
| Application: | APLNR / APJ receptor ligand |
| MW: | 1533.8 D |
215.00€
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Apelin receptor (Aplnr), partial, mouse, recombinant
Item number: CSB-EP001910MO1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 307-377aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: YAFFDPRFRQ ACTSMLCCDQ SGCKGTPHSS SAEKSASYSS GHSQGPGPNM GKGGEQMHEK SIPYSQETLV D. Purity: Greater than 85% as determined by...
| Keywords: | MSR, Aplnr, Agtrl1, Apelin receptor, Angiotensin receptor-like 1, G-protein coupled receptor APJ, Recombinant Mouse Apelin... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 15.1 kD |
From 364.00€
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Human APLNR Protein, hFc Tag
Item number: DIM-PME101471.10
Recombinant human APLNR Protein with C-terminal human Fc tag. APLNR(Met1-Ser26) hFc(Glu99-Ala330), Protein function: Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199, PubMed:25639753,...
| Keywords: | APJ, APJR, HG11, AGTRL1 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 29.2 kD |
From 129.00€
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APLNR (human) full length protein-synthetic nanodisc
Item number: DIM-FLP100132.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Keywords: | APLNR, AGTRL1, Apelin receptor, Angiotensin receptor-like 1, G-protein coupled receptor APJ, G-protein coupled receptor... |
| Application: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 42.7 kD |
From 1,291.00€
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Anti-APLNR
Item number: CSB-PA007868.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
| Application: | ELISA, WB, IHC, IF |
| Host: | Rabbit |
| Species reactivity: | human |
126.00€
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Anti-APLNR
Item number: CSB-PA165028.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: APLNR. Antigen Species: Human
| Keywords: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-APLNR
Item number: CSB-PA229044.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: APLNR. Antigen Species: Human
| Keywords: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
| Application: | ELISA, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Anti-APLNR
Item number: CSB-PA963250.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: APLNR. Antigen Species: Human
| Keywords: | Anti-APLNR, Anti-AGTRL1, Anti-Apelin receptor, Anti-Angiotensin receptor-like 1, Anti-G-protein coupled receptor APJ,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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Apelin-13 (trifluoroacetate salt)
Item number: Cay13523-25
The apelin gene encodes a pre-proprotein that is processed to generate bioactive peptides consisting of 36, 17, or 13 amino acids (apelin-36, apelin-17, and apelin-13, respectively). Apelin-13 is the endogenous ligand of the APJ receptor, activating this G protein-coupled receptor with an EC50 value of 0.37 nM (the...
| Keywords: | L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenyl... |
| Application: | APJ receptor ligand |
| MW: | 1550.8 D |
From 78.00€
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ML-233
Item number: Cay15187-1
The apelin receptor (APJ) signaling pathway mediates cardiovascular homeostasis and is involved in the pathogenesis of cardiovascular diseases. ML-233 is a novel APJ agonist (EC50 = 3.7 µM) that is >21-fold selective over the closely related angiotensin 1 receptor (EC50 = >79 µM).Formal Name:...
| Keywords: | CID-46905036, (E)-4-methyl-5-(((phenylsulfonyl)oxy)imino)-[1,1'-bi(cyclohexane)]-3,6-dien-2-one |
| Application: | APLNR agonist |
| MW: | 359.4 D |
From 62.00€
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