234 products were found matching "K04157"!
No results were found for the filter!
NEW
IHCH-7079
Item number: Cay41988-1
IHCH-7079 is a beta-arrestin-biased agonist of the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 16.98 nM). It reduces the time spent immobile in the tail suspension and forced swim tests in mice in a model of acute restraint stress-induced depression when administered at a dose of 10 mg/kg, and this effect can be...
| Keywords: | 2,3,6bR,7,8,9,10,10aS-octahydro-8-[2-(2-methoxyphenyl)ethyl]-3-methyl-1H-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxaline |
| Application: | 5-HT2A beta-arrestin-biased agonist |
| CAS | 2957888-63-8 |
| MW: | 363.5 D |
From 116.00€
*
SB 243213 dihydrochloride
Item number: TGM-T12859L-1mg
Description: SB 243213 dihydrochloride is an orally active, selective, and high-affinity antagonist of the 5-hydroxytryptamine (5-HT)2C receptor, with a pKi of 9.37 and a pKb of 9.8 for the human 5-HT2C receptor. Target: 5-HT Receptor. Smiles: O=C(N1C2=C(CC1)C=C(C)C(C(F)(F)F)=C2)NC3=CN=C(C=C3)OC4=CC=CN=C4C.Cl.Cl....
| Application: | 5-HT2C receptor inverse agonist |
| CAS | 1780372-25-9 |
| MW: | 501.33 D |
From 108.00€
*
(Rac)-WAY-161503
Item number: TGM-T13332-100mg
Description: (Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor [Ki: 4 nM, EC50: 12 nM], exhibiting anti-obesity and antidepressant effects. Target: 5-HT Receptor. Smiles: Clc1cc2NC(=O)C3CNCCN3c2cc1Cl. References: Halberstadt AL, et al. 5-HT(2A) and 5-HT(2C) receptors exert opposing...
| Application: | 5-HT2C receptor agonist |
| CAS | 75704-24-4 |
| MW: | 272.13 D |
From 84.00€
*
Lysergol
Item number: TGM-T15824-100mg
Description: Lysergol has been used as a hypotensive, psychotropic analgesic, and uterus- and intestine-stimulating drug. Lysergol is a clavinet alkaloid isolated from seeds of Ipomoea muricata and is a bioenhancer for the drugs and nutrients and has antibacterial activity. Target: Antibacterial. Smiles:...
| Application: | Ergot alkaloid, 5-HT1A/5-HT2A/5-HT2C receptor agonist |
| CAS | 602-85-7 |
| MW: | 254.33 D |
From 55.00€
*
Cyamemazine
Item number: TGM-T15026-100mg
Description: Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity. Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist with Ki values of 12 nM, 1.5 nM, and 75 nM, respectively. Target: 5-HT Receptor. Smiles: N#CC1=CC=C2SC=3C=CC=CC3N(C2=C1)CC(C)CN(C)C. References: Bourin M, et al....
| Application: | Targets 5-hydroxytryptamine receptor 2 (HTR2) |
| CAS | 3546-03-0 |
| MW: | 323.46 D |
From 128.00€
*
Agomelatine
Item number: TGM-T1445-100mg
Description: Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. Target: 5-HT Receptor, Melatonin Receptor. Smiles: COC1=CC=C2C=CC=C(CCNC(C)=O)C2=C1....
| Keywords: | S-20098, Thymanax, Valdoxan |
| Application: | Targets 5-hydroxytryptamine receptor 2 (HTR2) |
| CAS | 138112-76-2 |
| MW: | 243.3 D |
From 56.00€
*
PRX-08066
Item number: TGM-T16669-100mg
Description: PRX-08066, a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist, induces selective vasodilation of pulmonary arteries. Target: 5-HT Receptor. Smiles: Fc1ccc(CN2CCC(CC2)Nc2ncnc3sc(Cl)cc23)cc1C#N. References: Porvasnik SL, et al. PRX-08066, a novel 5-hydroxytryptamine receptor 2B...
| Application: | 5-HT2B receptor antagonist |
| CAS | 866206-54-4 |
| MW: | 401.89 D |
From 54.00€
*
Ritanserin
Item number: TGM-T16759-100mg
Description: Ritanserin (R 55667) is a highly effective, relatively selective, long-acting 5-HT2 receptor antagonist (IC50: 0.9 nM), with less activity on Histamine H1, Dopamine D2, Adrenergic alpha1, and Adrenergic alpha2 receptors. Target: 5-HT Receptor, Adrenergic Receptor, Dopamine Receptor, Histamine...
| Keywords: | R 55667 |
| Application: | Targets 5-hydroxytryptamine receptor 2 (HTR2) |
| CAS | 87051-43-2 |
| MW: | 477.57 D |
From 34.00€
*
Pimavanserin
Item number: TGM-T2076-100mg
Description: Pimavanserin (ACP-103)(ACP-103) is an effective and specific 5-HT2A receptor inverse agonist (mean pIC50: 8.7, in the cell-based functional assay). Pimavanserin is an atypical antipsychotic used in the treatment of hallucinations and psychosis in patients with Parkinson disease. Target: 5-HT Receptor....
| Keywords: | ACP-103 |
| Application: | HTR2A inverse agonist |
| CAS | 706779-91-1 |
| MW: | 427.55 D |
From 30.00€
*
Lurasidone
Item number: TGM-T21337-5mg
Description: Lurasidone (SM-13496) is an antagonist of dopamine D2 and 5-HT7 receptors (IC50 = 1.68 and 0.495 nM, respectively) and a partial agonist of the 5-HT1A receptor (IC50 = 6.75 nM). Target: 5-HT Receptor, Dopamine Receptor. Smiles:...
| Keywords: | SM-13496 |
| Application: | HTR1A / HTR2 / HTR7 / DRD2 modulator |
| CAS | 367514-87-2 |
| MW: | 492.68 D |
From 39.00€
*
Tedatioxetine
Item number: TGM-T34795-100mg
Description: Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Tedatioxetine acts as a CYP2D6 substrate. Target: Dopamine Receptor, Serotonin Transporter. Smiles: S(C1=CC=C(C=C1)C)C=2C=CC=CC2C3CCNCC3. References: Javelot H....
| Keywords: | Lu AA-24530, Lu AA24530, Lu AA 24530 |
| Application: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 508233-95-2 |
| MW: | 283.43 D |
From 286.00€
*
Setoperone
Item number: TGM-T34626-100mg
Description: Setoperone, as a sensitive radioligand, can be commonly used in position emission tomography (PET) imaging. Target: Others. Smiles: O=C1N2C(=NC(C)=C1CCN3CCC(C(=O)C4=CC=C(F)C=C4)CC3)SCC2. References: Beversdorf DQ, Nordgren RE, Bonab AA, Fischman AJ, Weise SB, Dougherty DD, Felopulos GJ, Zhou FC, Bauman...
| Keywords: | R 52245, R52245, R-52245 |
| Application: | Targets 5-hydroxytryptamine receptor 2 (HTR2) |
| CAS | 86487-64-1 |
| MW: | 401.5 D |
From 1,491.00€
*