219 products were found matching "K04153"!
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Tandospirone
Item number: TGM-TQ0315-1mL
Description: Tandospirone (SM-3997) is a selective partial agonist of the 5-HT1A receptor (Ki: 27 nM) with marked selectivity over SR-2, SR-1C, alpha1, alpha2, D1, and D2 receptors (Kis: 1300-41000 nM). Target: 5-HT Receptor. Smiles: O=C1[C@H]2[C@@H]3CC[C@@H](C3)[C@H]2C(=O)N1CCCCN1CCN(CC1)c1ncccn1. References: Hamik...
| Keywords: | SM-3997 |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 87760-53-0 |
| MW: | 383.49 D |
From 42.00€
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L-694,247
Item number: TGM-T19701-10mg
Description: L-694,247 is a selective and extremely potent agonist of the 5-HT1D receptor. Target: Others. Smiles: C(CN)C=1C=2C(=CC=C(C2)C3=NC(CC4=CC=C(NS(C)(=O)=O)C=C4)=NO3)NC1. References: De Castro-e-Silva E, Sarmento C, Nascimento TA, Luz CP, Soares T, Marinho A, Cunha M, Bulcäo C, De Oliveira IR, Fregoneze JB....
| Application: | 5-HT1D receptor agonist |
| CAS | 137403-12-4 |
| MW: | 411.48 D |
From 75.00€
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BRL-15572 dihydrochloride
Item number: TGM-T6423-100mg
Description: BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor. Target: 5-HT Receptor. Smiles: Cl.OC(CN1CCN(CC1)c1cccc(Cl)c1)C(c1ccccc1)c1ccccc1....
| Keywords: | BRL 15573 dihydrochloride |
| Application: | 5-HT1D receptor antagonist |
| CAS | 193611-72-2 |
| MW: | 479.87 D |
From 43.00€
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SB-224289 hydrochloride
Item number: TGM-T12841-10mg
Description: SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect. Target: 5-HT Receptor. Smiles: Cl.CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1. References: Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine...
| Keywords: | SB-224289A |
| Application: | 5-HT1B inverse agonist |
| CAS | 180084-26-8 |
| MW: | 557.08 D |
From 50.00€
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Vilazodone-d8
Item number: TGM-T13300-1mg
Description: Vilazodone D8 is a deuterium-labeled vilazodone. Vilazodone is a combined inhibitor of serotonin specific reuptake (SSRI) and agonist of 5-HT1A receptor partial. Smiles: [2H]C1([2H])N(CCCCc2c[nH]c3ccc(cc23)C#N)C([2H])([2H])C([2H])([2H])N(c2ccc3oc(cc3c2)C(N)=O)C1([2H])[2H]
| Application: | Serotonin antagonist and reuptake inhibitor (SARI), GC-MS, LC-MS, internal standard |
| CAS | 1794789-93-7 |
| MW: | 449.57 D |
From 351.00€
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NAN-190 hydrobromide
Item number: TGM-T12172-100mg
Description: NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT. Target: 5-HT Receptor. Smiles: Br.COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1. References: Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014...
| Application: | 5-HT1A receptor mixed antagonist / partial agonist |
| CAS | 115338-32-4 |
| MW: | 474.39 D |
From 35.00€
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Naluzotan
Item number: TGM-T16265-1mg
Description: Naluzotan(PRX 00023) is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+ channel blocker with an IC50 value of 3800 nM.Naluzotan exhibits anxiolytic activity and can be used to study depression. Target: EGFR, 5-HT...
| Keywords: | PRX 00023 |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 740873-06-7 |
| MW: | 450.64 D |
From 700.00€
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Rizatriptan
Item number: TGM-T1734L-5mg
Description: Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor. Target: Others. Smiles: CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12. References: Tradtrantip L, Jin BJ, Yao X, Anderson MO, Verkman AS. Aquaporin-Targeted Therapeutics: State-of-the-Field. Adv Exp Med Biol. 2017,969:239-250. doi:...
| Keywords: | Risatriptan, MK 462 free base |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 144034-80-0 |
| MW: | 269.34 D |
970.00€
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Pizotifen
Item number: TGM-T1442-100mg
Description: Pizotifen (Pizotyline) is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic...
| Keywords: | Pizotyline, BC-105 |
| Application: | Targets 5-hydroxytryptamine receptor 2 (HTR2) |
| CAS | 15574-96-6 |
| MW: | 295.44 D |
From 38.00€
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Rizatriptan benzoate
Item number: TGM-T1512-100mg
Description: Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches. Target: 5-HT Receptor. Smiles: c1cccc(c1)C(=O)O.[nH]1cc(c2cc(ccc12)Cn1ncnc1)CCN(C)C. References: Williamson DJ, et al. Br J...
| Keywords: | MK-462 Benzoate |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 145202-66-0 |
| MW: | 391.47 D |
From 41.00€
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Flesinoxan
Item number: TGM-T16711-100mg
Description: Flesinoxan, a hypotensive agent, is an effective, high-affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM). Target: 5-HT Receptor. Smiles: OC[C@@H]1COc2c(O1)cccc2N1CCN(CCNC(=O)c2ccc(F)cc2)CC1. References: Hadrava V, et al. Characterization of 5-hydroxytryptamine1A properties of...
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 98206-10-1 |
| MW: | 415.46 D |
From 371.00€
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1-(1-Naphthyl) piperazine hydrochloride
Item number: TGM-T21569-100mg
Description: 1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple serotonin (5-HT) receptors. Target: Others. Smiles: Cl.C1CN(CCN1)C1=CC=CC2=CC=CC=C12. References: Lee M , Rangisetty J B , Pullagurla M R , et al....
| Keywords: | 1-(Naphthalen-1-yl)piperazine hydrochloride, 1-naphthalen-1-ylpiperazine hydrochloride |
| Application: | 5-HT1 serotonin receptor agonist, 5-HT2 serotonin receptor antagonist |
| CAS | 104113-71-5 |
| MW: | 248.75 D |
From 52.00€
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