232 products were found matching "K04153"!
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L-694,247
Item number: TGM-T19701-10mg
Description: L-694,247 is a selective and extremely potent agonist of the 5-HT1D receptor. Target: Others. Smiles: C(CN)C=1C=2C(=CC=C(C2)C3=NC(CC4=CC=C(NS(C)(=O)=O)C=C4)=NO3)NC1. References: De Castro-e-Silva E, Sarmento C, Nascimento TA, Luz CP, Soares T, Marinho A, Cunha M, Bulcäo C, De Oliveira IR, Fregoneze JB....
| Application: | 5-HT1D receptor agonist |
| CAS | 137403-12-4 |
| MW: | 411.48 D |
From 75.00€
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BRL-15572 dihydrochloride
Item number: TGM-T6423-100mg
Description: BRL-15572 dihydrochloride (BRL 15573 dihydrochloride) is a 5-HT1D receptor antagonist with pKi of 7.9, also shows a considerable affinity at 5-HT1A and 5-HT2B receptors, exhibiting 60-fold selectivity over 5-HT1B receptor. Target: 5-HT Receptor. Smiles: Cl.OC(CN1CCN(CC1)c1cccc(Cl)c1)C(c1ccccc1)c1ccccc1....
| Keywords: | BRL 15573 dihydrochloride |
| Application: | 5-HT1D receptor antagonist |
| CAS | 193611-72-2 |
| MW: | 479.87 D |
From 42.00€
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Naluzotan hydrochloride
Item number: TGM-T68113-100mg
Description: Naluzotan hydrochloride (PRX 00023 hydrochloride) is a hERG K+ channel blocker with an IC50 value of 3800 nM and is commonly used in the study of anxiety and depression.Naluzotan hydrochloride is also a novel, potent, and selective 5-HT1A agonist, with an IC50 value of about 20 nM and a Ki value of...
| Keywords: | PRX 00023 hydrochloride |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 740873-82-9 |
| MW: | 487.1 D |
From 229.00€
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Vilazodone Hydrochloride
Item number: TGM-T6232-100mg
Description: Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder. Target: Serotonin Transporter, 5-HT Receptor, Others. Smiles:...
| Keywords: | Vilazodone HCl, EMD 68843, SB659746A |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 163521-08-2 |
| MW: | 477.99 D |
From 38.00€
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SEP-363856
Item number: TGM-T12899-100mg
Description: SEP-363856 is an agent of orally active and CNS active psychotropic with a unique, non-D2/5-HT2A mechanism of action, exerts its antipsychotic-like effects, has the potential to treatment of schizophrenia. Target: Others. Smiles: C(NC)[C@H]1C2=C(C=CS2)CCO1. References: Dedic N, et al. SEP-363856, a...
| Keywords: | SEP-856 |
| Application: | Targets trace amine associated receptor (TAAR) |
| CAS | 1310426-33-5 |
| MW: | 183.27 D |
From 1,520.00€
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SEP-363856 hydrochloride
Item number: TGM-T12899L-100mg
Description: SEP-363856 hydrochloride (SEP-856 hydrochloride) is an orally active, CNS-active psychotropic agent with a unique non-D2/5-HT2A mechanism of action, demonstrating antipsychotic-like effects and potential for schizophrenia treatment. Target: Others, 5-HT Receptor. Smiles: Cl.CNC[C@@H]1OCCc2ccsc12....
| Keywords: | SEP-856 hydrochloride |
| Application: | Targets trace amine associated receptor (TAAR) |
| CAS | 1310422-41-3 |
| MW: | 219.73 D |
From 63.00€
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Vilazodone
Item number: TGM-T1279-10mg
Description: Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from the synaptic cleft while stimulating the release of 5-HT into the synaptic cleft....
| Keywords: | EMD 68843, SB659746A |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 163521-12-8 |
| MW: | 441.52 D |
From 55.00€
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SB-224289 hydrochloride
Item number: TGM-T12841-10mg
Description: SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect. Target: 5-HT Receptor. Smiles: Cl.CN1CCC2(COc3cc4CCN(C(=O)c5ccc(cc5)-c5ccc(cc5C)-c5noc(C)n5)c4cc23)CC1. References: Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine...
| Keywords: | SB-224289A |
| Application: | 5-HT1B inverse agonist |
| CAS | 180084-26-8 |
| MW: | 557.08 D |
From 48.00€
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Vilazodone-d8
Item number: TGM-T13300-1mg
Description: Vilazodone D8 is a deuterium-labeled vilazodone. Vilazodone is a combined inhibitor of serotonin specific reuptake (SSRI) and agonist of 5-HT1A receptor partial. Smiles: [2H]C1([2H])N(CCCCc2c[nH]c3ccc(cc23)C#N)C([2H])([2H])C([2H])([2H])N(c2ccc3oc(cc3c2)C(N)=O)C1([2H])[2H]
| Application: | Serotonin antagonist and reuptake inhibitor (SARI), GC-MS, LC-MS, internal standard |
| CAS | 1794789-93-7 |
| MW: | 449.57 D |
From 343.00€
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NAN-190 hydrobromide
Item number: TGM-T12172-100mg
Description: NAN-190 hydrobromide is an antagonist of serotonin receptor 5-HT. Target: 5-HT Receptor. Smiles: Br.COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1. References: Shahane SA, et al. Detection of phospholipidosis induction: a cell-based assay in high-throughput and high-content format. J Biomol Screen. 2014...
| Application: | 5-HT1A receptor mixed antagonist / partial agonist |
| CAS | 115338-32-4 |
| MW: | 474.39 D |
From 33.00€
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Naluzotan
Item number: TGM-T16265-1mg
Description: Naluzotan(PRX 00023) is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+ channel blocker with an IC50 value of 3800 nM.Naluzotan exhibits anxiolytic activity and can be used to study depression. Target: EGFR, 5-HT...
| Keywords: | PRX 00023 |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 740873-06-7 |
| MW: | 450.64 D |
From 699.00€
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Rizatriptan
Item number: TGM-T1734L-5mg
Description: Rizatriptan is an agonist of the serotonin-1b and serotonin-1d receptor. Target: Others. Smiles: CN(C)CCc1c[nH]c2ccc(Cn3cncn3)cc12. References: Tradtrantip L, Jin BJ, Yao X, Anderson MO, Verkman AS. Aquaporin-Targeted Therapeutics: State-of-the-Field. Adv Exp Med Biol. 2017,969:239-250. doi:...
| Keywords: | Risatriptan, MK 462 free base |
| Application: | Targets 5-hydroxytryptamine receptor 1 (HTR1) |
| CAS | 144034-80-0 |
| MW: | 269.34 D |
31.00€
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