144 products were found matching "K04145"!

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 214-373aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: IVLRRRRKRV NTKRSSRAFR AHLRAPLKGN CTHPEDMKLC TVIMKSNGSF PVNRRRVEAA RRAQELEMEM LSSTSPPERT RYSPIPPSHH QLTLPDPSHH GLHSTPDSPA...

Fluphenazine decanoate is a prodrug form of the dopamine D1 and D2 receptor antagonist fluphenazine (Cay-23555). It induces random mouth movements in rats, an effect that can be reversed by the dopamine receptor antagonists raclopride (Cay-17422) or SCH 23390 (Cay-15631). Chronic administration of fluphenazine...

Metoclopramide is a dual antagonist of the serotonin (5-HT) receptor subtype 5-HT3 and dopamine D2 receptor (IC50s = 308 and 483 nM, respectively). It also reversibly inhibits acetylcholinesterase (AChE) isolated from human postmortem caudate nucleus (Kis = 9.3 and 82 µM for competitive and non-competitive...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human DRD2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human DRD2. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat DRD2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat DRD2. Next,...

Risperidone is an atypical antipsychotic that binds to dopamine D2 receptors (Ki = 3 nM) and the serotonin (5-HT) receptor subtype 5-HT2A (Ki = 0.12 nM). It also binds to dopamine D4, alpha1- and alpha2-adrenergic, 5-HT1C, 5-HT1D, and histamine H1 receptors (Kis = 7, 0.81, 7.3, 47, 52, and 2.1 nM, respectively)....

Haloperidol is a typical antipsychotic and dopamine D2-like receptor antagonist (Kis = 0.6, 0.2, and 22 nM, for D2, D3, and D4 receptors, respectively). It also acts as an inverse agonist at dopamine D2 and D3 receptors (IC50s = 0.8 and 0.6 nM, respectively). Haloperidol also binds to alpha1- and alpha2- adrenergic...

Trifluoperazine (TFP) is a phenothiazine compound with anti-adrenergic and anti-dopaminergic actions typical of antipsychotic agents. It antagonizes adrenergic receptors, with selectivity for alpha1 over the alpha2 subtypes (Kis = 24, 653, 163, and 391 nM for alpha1A, alpha2A, alpha2B, and alpha2C, respectively)....

Thioridazine is a typical antipsychotic. It binds to dopamine D2, histamine H1, M3 muscarinic, and alpha1- and alpha2-adrenergic receptors (Kis = 5-341.3 nM), as well as the serotonin (5-HT) receptor subtypes 5-HT1A, 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 (Kis = 10-180.7 nM). Thioridazine (5 mg/kg) reduces...

(-)-Apomorphine (hydrochloride) (Cay-34222) is an analytical reference standard categorized as a dopamine receptor agonist. This product is intended for analytical forensic applications. This product is also available as a general research tool (Cay-16094).Formal Name:...

Bromocriptine is a dopamine receptor agonist (Kis = 1,659, 12.2, 12.2, 59.7, and 1,691 nM for dopamine D1, D2, D3, D4, and D5 receptors, respectively). It also binds to the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1D (Kis = 12.9 and 10.7 nM, respectively), as well as alpha1-adrenergic receptors (Kis =...

Used for the treatment of schizophrenia. Used for the treatment of acute manic and mixed episodes associated with bipolar disorder, and as an adjunct for the treatment of depression.