53 products were found matching "K04143"!

Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-408aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MAPWPHENSS LAPWPDLPTL APNTANTSGL PGVPWEAALA GALLALAVLA TVGGNLLVIV AIAWTPRLQT MTNVFVTSLA AADLVMGLLV VPPAATLALT GHWPLGATGC...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ADRb3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ADRb3. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ADRb3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ADRb3. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ADRb3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ADRb3. Next,...

Mirabegron is an agonist of the beta3-adrenergic receptor (beta3-AR). It induces cAMP accumulation in CHO cells expressing the beta3-AR but not the beta1- or beta2-AR (EC50s = 0.0224, >10, and >10 µM, respectively). Mirabegron reduces contraction induced by carbamoylcholine (Cay-14486) of isolated rat and human...

L-755,507 is a partial agonist of beta3-adrenergic receptors (EC50 = 0.43 nM). It displays more than 440-fold selectivity for beta3- over beta1- and beta2-adrenoceptors (EC50s = 580 and >10,000 nM, respectively). At 5 µM, this compound has been used to enhance CRISPR-mediated homology-directed repair efficiency by...

A beta-adrenergic agonist.

CL 316,243 is a beta3-adrenoceptor agonist (EC50 = 3 nM) that is >10,000-fold selective over beta1 and beta2. It causes a rapid decrease in blood glucose level in mice and has been used to study the induction of brown adipocytes and to increase thermogenesis in a mouse model of dietary obesity.Formal Name:...

SR 59230A (hydrochloride) is a beta3-adrenergic receptor (beta3-AR) antagonist (pA2s = 8.76, 7.31, and 6.63 in rat proximal colon, guinea pig atrium, and guinea pig trachea, respectively). It is less selective for beta3-AR in cells transfected with the human beta-AR subtypes (Kis = 16.4, 61.9, and 122 nM for beta1-,...

SR 58611A is a selective beta3-adrenergic receptor agonist (beta3-AR, EC50 = 3.5 nM in rat colon). Its activity cannot be blocked by the beta1- and beta2-AR antagonists CGP 20712A and ICI 118551 (Cay-15591), respectively. SR 58611A is minimally active against beta1-ARs in rat uterus (EC50 = 499 nM) and inactive...

Alprenolol is a non-selective beta-adrenergic receptor (beta-AR) antagonist that is also an antagonist of the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1B. It binds to beta1-, beta2-, and beta3-ARs expressed in CHO cells (Kds = 15, 0.91, and 117 nM, respectively, for the human receptors) and to 5-HT1A and...

BRL 37344 is a selective agonist of beta3-adrenergic receptors with Ki values of 0.43, 9.17, and 37.9 µM for beta3, beta2, and beta1, respectively. beta3-Adrenoceptors are expressed in adipose tissue as well as endothelial and myocardial tissues. This compound has been used to explore the role of these receptors in...