52 products were found matching "K04137"!

Description: BMY 7378 dihydrochloride (BMY7378 HCl) , alpha1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor. Target: Adrenergic Receptor, 5-HT Receptor, Dopamine Receptor. Smiles: Cl.COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1.Cl. References: Cleary L, et al. Auton...

Description: Prazosin-d8 is a deuterated compound of Prazosin. Smiles: [2H]C1([2H])N(C(=O)C2=CC=CO2)C([2H])([2H])C([2H])([2H])N(C2=NC3=C(C=C(OC)C(OC)=C3)C(N)=N2)C1([2H])[2H]

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1D (ADRA1D). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1D. In addition to ADRA1D Reporter Cells, this kit...

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1D (ADRA1D). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1D. In addition to ADRA1D Reporter Cells, this kit...

(-)-Norepinephrine is the endogenous isomer of (±)-norepinephrine (Cay-35580) that acts as a neurotransmitter and hormone and is biosynthesized from dopamine by dopamine beta-hydroxylase. It is an agonist of adrenergic receptors (Ki values are 330, 56, and 740 nM for alpha1, alpha2, and beta1 adrenoceptors,...

Acetylcholine is a neurotransmitter that binds to nicotinic and muscarinic acetylcholine receptors (AChRs) in the central and peripheral nervous systems. It mediates motor function at the neuromuscular junction but also has functions in the parasympathetic and sympathetic nervous systems. It is involved in learning...

Phentolamine is a reversible antagonist of alpha-adrenergic receptors, non-specifically binding all alpha1- and alpha2-adrenoceptors with nanomolar affinities. Formulations containing phentolamine have been used in the treatment of hypertensive emergencies, as well as chronic and emergent pain.Formal Name:...

Prazosin is an antagonist of alpha1-adrenergic receptors (alpha1-ARs). It selectively binds to alpha1-ARs with Ki values of 0.2, 0.25, and 0.32 nM for the human recombinant alpha1A-, alpha1B-, and alpha1D-ARs, respectively, over alpha2-ARs (Kis = 340 and 3.7 nM in alpha2A-AR-expressing HT-29 cells and...

White solid. An alpha1-adrenergic antagonist. In addition, it has high affinity and selectivity for central 5-hydroxytryptamine binding sites and inhibits platelet aggregation.

A biogenic amine present in herbal products and citrus juices. It has antidepressant-like effects by stimulating alpha1-adrenoceptors in mice.

Risperidone (Cay-13629) is a benzisoxazole derivative used for treating schizophrenia, and also the psychotic, affective, or behavioral symptoms associated with other disorders. Methyl 5,6,7,8-tetradehydro risperidone is used as an internal standard used in the quantitative analysis of risperidone.Formal Name:...

Risperidone E-oxime is a potential impurity found in commercial preparations of risperidone. Risperidone (Cay-13629) is a longer-acting benzisoxazole derivative used for treating schizophrenia, and also the psychotic, affective, or behavioral symptoms associated with other disorders. This second-generation...