57 products were found matching "K04136"!

Description: Desglymidodrine is a Metabolite of midodrine (ST-1085). It is used in plasma of ascitic patients. Target: Others. Smiles: COC1=CC(C(O)CN)=C(OC)C=C1. References: Ali AA, Al-Ghobashy MA, Farid SF, Kassem MA. Development and validation of LC-MS/MS assay for the determination of the prodrug Midodrine and...

Description: Rec 15/2615 is an antagonist of alpha1B-adrenergic receptors (alpha1B-ARs, Ki = 0.45 nM for the recombinant human receptor).1 It selectively inhibits alpha1B-ARs over alpha1A-, alpha1D-, and alpha1L-ARs (Kis = 7.59, 10.23, and 49 nM, respectively). Rec 15/2615 inhibits norepinephrine-induced...

Description: Midodrine D6 hydrochloride is a vasopressor/antihypotensive agent. Smiles: Cl.[2H]C([2H])([2H])Oc1ccc(OC([2H])([2H])[2H])c(c1)C(O)CNC(=O)CN

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ADRA1B. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ADRA1B. Antigen Species: Human

Desglymidodrine is the active metabolite of the prodrug midodrine (Cay-17349). It is formed from midodrine by enzymatic hydrolysis. Desglymidodrine is an agonist of alpha1-adrenergic receptors (alpha1-ARs). It binds to alpha1-ARs (Kis = 9.77, 9.55, and 8.51 µM for alpha1A, alpha1B, and alpha1D-ARs, respectively) and...

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1B (ADRA1B). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1B. In addition to ADRA1B Reporter Cells, this kit...

This is an all-inclusive cell-based luciferase reporter assay kit targeting the the Human Adrenoreceptor Alpha 1B (ADRA1B). INDIGO's ADRA1A reporter assay utilizes proprietary mammalian cells that have been engineered to provide constitutive expression of the ADRA1B. In addition to ADRA1B Reporter Cells, this kit...

(-)-Norepinephrine is the endogenous isomer of (±)-norepinephrine (Cay-35580) that acts as a neurotransmitter and hormone and is biosynthesized from dopamine by dopamine beta-hydroxylase. It is an agonist of adrenergic receptors (Ki values are 330, 56, and 740 nM for alpha1, alpha2, and beta1 adrenoceptors,...

Urapidil is an antagonist of alpha1-adrenergic receptors (alpha1-ARs) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. It selectively binds to alpha1- over alpha2-ARs (IC50s = 0.74 and 42 µM, respectively) and to 5-HT1A over 5-HT1B and 5-HT2 receptors (IC50s = 0.4, 20.4, and >10 µM,...

Doxazosin is a non-selective antagonist of alpha1-adrenergic receptors (alpha1-ARs, Kis = 3.16, 1, and 3.98 nM for alpha1A­-, alpha1B-, and alpha1D-ARs, respectively). It inhibits norepinephrine-induced contractions in isolated rat aorta rings and human prostate strips with pA2 values of 8.8 and 8.2, respectively....