99 products were found matching "K04131"!
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Navafenterol
Item number: TGM-T30264-5mg
Description: AZD-8871 can present a novel treatment approach to chronic obstructive pulmonary disease [COPD] and potentially also asthma (in combination with an inhaled corticosteroid [ICS]). Target: Others. Smiles:...
| Keywords: | LAS-191351, AZD8871, LAS 191351, LAS191351, AZD-8871, AZD 8871 |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 1435519-06-4 |
| MW: | 742.91 D |
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Navafenterol saccharinate
Item number: TGM-T30265-25mg
Description: AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD). Target: Others. Smiles:...
| Keywords: | AZD-8871 saccharinate, LAS191351 saccharinate, LAS-191351 saccharinate, AZD8871 saccharinate |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 1648550-37-1 |
| MW: | 926.09 D |
1,520.00€
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Sofpironium bromide
Item number: TGM-T28827-100mg
Description: Sofpironium bromide (BBI4000) belongs to a class of drugs called anticholinergics, which exert their effect by blocking the action of acetylcholine. Target: AChR, Others. Smiles: [Br-].CCOC(=O)C[N+]1(C)CC[C@H](C1)OC(=O)[C@@](O)(C1CCCC1)c1ccccc1. References: Julia Paik, et al. Sofpironium Bromide: First...
| Keywords: | BBI4000, BBI 4000, BBI-4000 |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 1628106-94-4 |
| MW: | 470.4 D |
From 67.00€
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Hexocyclium metilsulfate
Item number: TGM-T27539-100mg
Description: Hexocyclium metilsulfate has anti-gastric secretory effects in humans. Target: Others. Smiles: O=S(=O)([O-])OC.OC(C=1C=CC=CC1)(CN2CC[N+](C)(C)CC2)C3CCCCC3. References: BRETTE R, LAMBERT R, HALLACQ A. [Action of urogastrone and hexocyclium methylsulfate on gastric secretion in man]. Arch Mal Appar Dig...
| Keywords: | AB803, AB-803, AB 803, Traline |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 115-63-9 |
| MW: | 428.59 D |
From 1,520.00€
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Isopropamide Iodide
Item number: TGM-T5051-100mg
Description: Isopropamide iodide is a long-acting anticholinergic drug used for peptic ulcers and other gastrointestinal disorders, and as a muscarinic receptor antagonist for diseases affecting cognition [including Alzheimer's disease]. Target: AChR. Smiles: [I-].CC(C)[N+](C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)C(C)C....
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 71-81-8 |
| MW: | 480.43 D |
From 37.00€
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Revefenacin
Item number: TGM-T7392-100mg
Description: Revefenacin (TD-4208) is a mAChR antagonist has a high affinity on M3 receptor( Ki : 0.18 nM),and potentially useful for the treatment of respiratory disease. Target: AChR. Smiles: CN(CCN1CCC(CC1)OC(=O)Nc1ccccc1-c1ccccc1)C(=O)c1ccc(CN2CCC(CC2)C(N)=O)cc1. References: Pulido-Rios MT, McNamara A, Obedencio...
| Keywords: | GSK1160724, TD-4208 |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 864750-70-9 |
| MW: | 597.75 D |
From 37.00€
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CHRM3 Protein, Human, Recombinant (B2M & His)
Item number: TGM-TMPH-01716-100ug
Description: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM3 Protein, Human, Recombinant (B2M &...
| Keywords: | CHRM3, Muscarinic acetylcholine receptor M3 |
| MW: | 40.7 kD |
From 198.00€
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Rociverine
Item number: TGM-T26112-100mg
Description: Rociverine is an anticholinergic compound used as a smooth muscle relaxant. Target: Others. Smiles: O[C@]1([C@@H](C(OC(CN(CC)CC)C)=O)CCCC1)C2CCCCC2. References: Cromi A, Ghezzi F, Agosti M, Uccella S, Piazza N, Serati M, Bolis P. Use of an antispasmodic (rociverine) to shorten the length of labor: a...
| Keywords: | Rociverinum |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 53716-44-2 |
| MW: | 339.51 D |
From 1,520.00€
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Desfesoterodine
Item number: TGM-T6364-100mg
Description: Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM. Target: AChR. Smiles: CC(C)N(CC[C@H](c1ccccc1)c1cc(CO)ccc1O)C(C)C. References: Nilvebrant L, et al. Pharmacol Toxicol, 1997, 81(4), 169-172.
| Keywords: | (R)-5-Hydroxymethyl Tolterodine, 5-HMT, PNU-200577, 5-HM, 5-hydroxymethyl Tolterodine |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 207679-81-0 |
| MW: | 341.49 D |
From 60.00€
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Tiotropium bromide
Item number: TGM-T1179-100mg
Description: Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to...
| Keywords: | BA679 BR, Tiopropium |
| Application: | Muscarinic cholinergic receptor antagonist |
| CAS | 136310-93-5 |
| MW: | 472.42 D |
From 45.00€
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Zamifenacin fumarate
Item number: TGM-T13385-100mg
Description: Zamifenacin fumarate (UK-76654 fumarate) is a potent, gut-selective antagonist of the muscarinic M3 receptor. Target: AChR. Smiles: OC(=O)\C=C\C(O)=O.C(Cc1ccc2OCOc2c1)N1CCC[C@H](C1)OC(c1ccccc1)c1ccccc1. References: Houghton LA, et al. Zamifenacin (UK-76, 654) a potent gut M3 selective muscarinic...
| Keywords: | UK-76654 fumarate |
| Application: | Muscarinic M3 receptor antagonist |
| CAS | 127308-98-9 |
| MW: | 531.6 D |
From 34.00€
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D-Panthenol
Item number: TGM-T1437-1g
Description: D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of D-Panthenol is...
| Keywords: | Dexpanthenol, Ilopan, Pantothenol, D-Pantothenyl alcohol |
| Application: | Targets muscarinic acetylcholine receptor M3 (CHRM3) |
| CAS | 81-13-0 |
| MW: | 205.25 D |
From 31.00€
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