139 products were found matching "K04010"!
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Avacopan
Item number: TGM-T8223-10mg
Description: Avacopan (CCX168) is an orally administered small-molecule C5aR ( IC50 : 0.1 nM.)antagonist that blocks the effects of C5a and prevents the development of GN induced by anti-myeloperoxidase antibodies in a murine model of AAV. Target: Complement System. Smiles:...
| Keywords: | CCX168 |
| Application: | Targets C5a anaphylatoxin chemotactic receptor 1 (C5AR1, CD88) |
| CAS | 1346623-17-3 |
| MW: | 581.64 D |
From 34.00€
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PMX-53 TFA
Item number: TGM-T83669-10mg
Description: PMX-53, a macrocyclic complement 5a (C5a) peptidomimetic and C5a receptor antagonist (IC50 = 0.3 µM), effectively inhibits the C5a-induced secretion of myeloperoxidase (MPO) in isolated human polymorphonuclear leukocytes (PMNs). Administered orally at 10 mg/kg, PMX-53 mitigates vascular leakage, PMN...
| Keywords: | AcPhe-[Orn-Pro-D-Cyclohexylalanine-Trp-Arg], 3D53, AcF-[OPdChaWR] |
| Application: | C5a receptor antagonist |
| CAS | 514814-99-4 |
| MW: | 896.09 D |
From 148.00€
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C5AR1 Protein-VLP, Human, Recombinant (His)
Item number: TGM-TMPH-01022-100ug
Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation...
| Keywords: | C5AR1, C5a-R, C5R1, C5a anaphylatoxin chemotactic receptor, C5AR, C5a anaphylatoxin chemotactic receptor 1, CD88 |
| MW: | 41.1 kD |
From 930.00€
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C5AR1 Protein, Human, Recombinant (Cell-Free, His)
Item number: TGM-TMPH-01023-100ug
Description: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation...
| Keywords: | C5a-R, C5R1, C5a anaphylatoxin chemotactic receptor 1, C5AR1, C5a anaphylatoxin chemotactic receptor, C5AR, CD88 |
| MW: | 40.7 kD |
From 1,982.00€
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W-54011
Item number: TGM-T17250-100mg
Description: W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki = 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils (IC50s = 3.1 nM, 2.7 nM, and 1.6 nM,...
| Application: | C5a Receptor Antagonist |
| CAS | 405098-33-1 |
| MW: | 493.08 D |
From 77.00€
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C5a anaphylatoxin chemotactic receptor (C5AR1), partial,...
Item number: CSB-EP003996HU1-B.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-37aa. Protein Length: Partial. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged. Target Protein Sequence: MDSFNYTTPD YGHYDDKDTL DLNTPVDKTS NTLRVPD. Purity: Greater than 90% as determined by SDS-PAGE. Endotoxin: n/a. Biological...
| Keywords: | C5AR, C5aR, CD88, C5AR1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 52.1 kD |
From 439.00€
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C5a anaphylatoxin chemotactic receptor (C5AR1), partial,...
Item number: CSB-EP003996HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-37aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-KSI-tagged. Target Protein Sequence: MDSFNYTTPD YGHYDDKDTL DLNTPVDKTS NTLRVPD. Purity: Greater than 95% as determined by SDS-PAGE. Endotoxin: n/a. Biological Activity: n/a. Form: Liquid or...
| Keywords: | C5AR, C5aR, CD88, C5AR1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 19.6 kD |
From 292.00€
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C5a anaphylatoxin chemotactic receptor (C5ar1), partial,...
Item number: CSB-EP003996MO1-B.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 306-351aa. Protein Length: Partial. Tag Info: N-terminal MBP-tagged and C-terminal 6xHis-Avi-tagged. Target Protein Sequence: QGFHGRLLRS LPSIIRNALS EDSVGRDSKT FTPSTTDTST RKSQAV. Purity: Greater than 95% as determined by SDS-PAGE. Endotoxin: n/a....
| Keywords: | C5ar, C5aR, CD88, C5ar1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 52.8 kD |
From 395.00€
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C5a anaphylatoxin chemotactic receptor (C5ar1), partial,...
Item number: CSB-EP003996MO1.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 306-351aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-KSI-tagged. Target Protein Sequence: QGFHGRLLRS LPSIIRNALS EDSVGRDSKT FTPSTTDTST RKSQAV. Purity: Greater than 95% as determined by SDS-PAGE. Endotoxin: n/a. Biological Activity: Not Test....
| Keywords: | C5ar, C5aR, CD88, C5ar1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | mouse |
| MW: | 20.4 kD |
From 247.00€
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C5a anaphylatoxin chemotactic receptor (C5AR1), human,...
Item number: CSB-CF003996HUd7.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-350aa. Protein Length: Full Length. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: MDSFNYTTPD YGHYDDKDTL DLNTPVDKTS NTLRVPDILA LVIFAVVFLV GVLGNALVVW VTAFEAKRTI NAIWFLNLAV ADFLSCLALP ILFTSIVQHH HWPFGGAACS...
| Keywords: | C5AR, C5aR, CD88, C5AR1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli in vitro |
| Origin: | human |
| MW: | 40.7 kD |
From 943.00€
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C5a anaphylatoxin chemotactic receptor 1 (C5AR1)-VLPs...
Item number: CSB-MP003996HU.1
Organism: Homo sapiens (Human). Source: Mammalian cell. Expression Region: 1-350aa. Protein Length: Full Length. Tag Info: C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions). Target Protein Sequence: MDSFNYTTPD YGHYDDKDTL DLNTPVDKTS NTLRVPDILA LVIFAVVFLV GVLGNALVVW VTAFEAKRTI...
| Keywords: | C5AR, C5aR, CD88, C5AR1, C5a-R, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1,... |
| Application: | Active protein |
| Expressed in: | Mammalian cells |
| Origin: | human |
| MW: | 41.1 kD |
From 526.00€
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Human C5AR1 Protein, hFc Tag
Item number: DIM-PME100830.10
Recombinant Human C5AR1 Protein with C-terminal human Fc tag. C5AR1(Met1-Asp37) hFc(Glu99-Ala330), Protein function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand...
| Keywords: | C5A, C5AR, C5R1, CD88 |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 30.4 kD |
From 148.00€
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