174 products were found matching "K03462"!
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SBI-797812
Item number: Cay41526-10
SBI-797812 is an activator of nicotinamide phosphoribosyltransferase (Nampt). It increases nicotinamide (NMN) levels and prevents NAD+ feedback inhibition in a cell-free assay using recombinant human Nampt when used at a concentration of 2 µM. In vivo, SBI-797812 (20 mg/kg) increases liver levels of NAD+ but does...
| Keywords: | N-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-ylsulfonyl)phenyl]-N'-(4-pyridinylmethyl)-urea |
| Application: | Nampt activator |
| CAS | 2237268-08-3 |
| MW: | 402.5 D |
From 108.00€
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Nampt (Visfatin/PBEF) (human) ELISA Kit
Item number: AG-45A-0006YEK-KI01
Nicotinamide phosphoribosyltransferase (Nampt, pre-B cell colony-enhancing factor, PBEF, Visfatin) is an 52kDA adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form...
| Keywords: | PBEF, NAMPT, Nampt, Visfatin, NAmPRTase, EC=2.4.2.12, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1,... |
| Application: | ELISA |
| Species reactivity: | human |
682.00€
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From 613.80€
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Teglarinad chloride
Item number: TGM-T26254-1mg
Description: Teglarinad chloride (GMX-1777 chloride) is a potent inhibitor of NAMPT, the precursor of GMX1778.Teglarinad chloride has antitumor activity and acts by interfering with DNA repair and inhibiting angiogenesis. Target: NAMPT. Smiles: [Cl-].COCCOCCOCC...
| Keywords: | GMX 1777, GMX-1777 chloride, GMX1777 chloride, GMX 1777 chloride, EB1627, GMX1777, EB-1627, EB-1627 chloride, EB1627 chloride |
| Application: | Targets nicotinamide phosphoribosyltransferase [EC:2.4.2.12] (NAMPT) |
| CAS | 432037-57-5 |
| MW: | 672.6 D |
205.00€
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beta-Nicotinamide mononucleotide
Item number: TGM-T4721-100mg
Description: beta-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). beta-nicotinamide mononucleotide is involved in a number of biochemical reactions in the human body, which are related to immunity and metabolism. Target: Others, Endogenous...
| Keywords: | NMN, beta-NM |
| Application: | NAD biosynthesis intermediate |
| CAS | 1094-61-7 |
| MW: | 334.22 D |
From 31.00€
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GNE-617
Item number: TGM-T4335-100mg
Description: GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer. Target: NAMPT. Smiles: Fc1cc(F)cc(c1)S(=O)(=O)c1ccc(CNC(=O)c2ccc3nccn3c2)cc1. References: Shames DS, et al. Loss of NAPRT1 Expression by Tumor-specific Promoter Methylation Provides a Novel Predictive Biomarker...
| Keywords: | GNE617 |
| Application: | NAMPT inhibitor |
| CAS | 1362154-70-8 |
| MW: | 427.42 D |
From 34.00€
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Nampt-IN-1
Item number: TGM-T4376-100mg
Description: Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM. Target: NAMPT, c-Fms, CSF-1R. Smiles: CC(C)(O)CS(=O)(=O)NC1=CC2=C(CN(CC2)C(=O)COC2=CC=CN=C2)C=C1. References: Zhao G, et al. Discovery of a Highly Selective NAMPT...
| Keywords: | LSN3154567 |
| Application: | Nicotinamide phosphoribosyltransferase inhibitor |
| CAS | 1698878-14-6 |
| MW: | 419.49 D |
From 33.00€
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NAMPT Protein, Human, Recombinant (His)
Item number: TGM-TMPJ-00968-10ug
Description: Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine "visfatin"....
| Keywords: | PBEF, Nicotinamide phosphoribosyltransferase, PBEF1, Visfatin, NAmPRTase, NAMPT, Pre-B cell-enhancing factor, Pre-B-cell... |
| MW: | 55 kD |
From 113.00€
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NAMPT Protein, Mouse, Recombinant (His)
Item number: TGM-TMPH-02810-100ug
Description: NAMPT Protein, Mouse, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 57.9 kDa and the accession number is Q99KQ4.
| Keywords: | Nicotinamide phosphoribosyltransferase, Nampt, Visfatin, Pre-B-cell colony-enhancing factor 1 homolog |
| MW: | 57.9 kD |
From 278.00€
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NAMPT Protein, Mouse, Recombinant
Item number: TGM-TMPH-03760-100ug
Description: NAMPT Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 55.6 kDa and the accession number is Q99KQ4.
| Keywords: | Nampt, Nicotinamide phosphoribosyltransferase, Visfatin, Pre-B-cell colony-enhancing factor 1 homolog |
| MW: | 55.6 kD |
From 383.00€
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NAMPT Protein, Mouse, Recombinant (HA & His)
Item number: TGM-TMPH-03761-100ug
Description: NAMPT Protein, Mouse, Recombinant (HA & His) is expressed in E. coli expression system with N-6xHis and C-HA tag. The predicted molecular weight is 60.6 kDa and the accession number is Q99KQ4.
| Keywords: | Visfatin, Nampt, Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog |
| MW: | 60.6 kD |
From 232.00€
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NAMPT Protein, Human, Recombinant (His & GST)
Item number: TGM-TMPY-02577-50ug
Description: Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme...
| Keywords: | VISFATIN, PBEF, PBEF1, 1110035O14Rik, VF, nicotinamide phosphoribosyltransferase |
| MW: | 83.3 kD |
299.00€
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NAMPT inhibitor-linker 1
Item number: TGM-T18477-100mg
Description: NAMPT inhibitor-linker 1, a drug-linker conjugate for ADC, integrates an NAMPT inhibitor (as a payload) with a linker. In the formulation of ADC-3, it pairs with an anti-c-Kit monoclonal antibody, demonstrating strong efficacy against c-Kit expressing cell lines, specifically GIST-T1 and NCI-H526, where...
| Application: | NAMPT inhibitor |
| CAS | 2241019-57-6 |
| MW: | 668.71 D |
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