49 products were found matching "K03178"!
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Ubiquitin Activating Enzyme E1/UBA1 Protein, Human,...
Item number: TGM-TMPY-02840-50ug
Description: UBE1, also known as UBA1, belongs to the ubiquitin-activating E1 family. UBE1 gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. UBE1 catalyzes the first step in ubiquitin conjugation...
| Keywords: | AMCX1, UBE1X, A1S9T, CTD-2522E6.1, A1S9, UBE1, SMAX2, UBA1A, ubiquitin-like modifier activating enzyme 1, CFAP124, POC20,... |
| MW: | 146 kD |
389.00€
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PYR-41
Item number: TGM-T6629-100mg
Description: PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with no activity at E2. Target: Apoptosis, E1/E2/E3 Enzyme. Smiles: CCOC(=O)c1ccc(cc1)N1NC(=O)\C(=C\c2ccc(o2)[N+]([O-])=O)C1=O. References: Yang Y, et al. Cancer Res, 2007, 67(19), 9472-9481.
| Keywords: | PYR 41, PYR41 |
| Application: | Cell-permeable, irreversible ubiquitin-activating enzyme (E1) inhibitor |
| CAS | 418805-02-4 |
| MW: | 371.3 D |
From 33.00€
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NSC624206
Item number: TGM-T12265-1mg
Description: NSC624206 is a ubiquitin E1 (UBA1) inhibitor(IC50 of ~9 µM). Target: Others. Smiles: Cl.CCCCCCCCCC NCCSSCc1ccc(Cl)cc1. References: Dana Ungermannova, et al. Identification and Mechanistic Studies of a Novel Ubiquitin E1 Inhibitor. J Biomol Screen . 2012 Apr,17(4):421-34.
| Application: | Ubiquitin-activating enzyme (E1) inhibitor |
| CAS | 13116-77-3 |
| MW: | 410.51 D |
From 77.00€
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TAK-243
Item number: TGM-T16974-100mg
Description: TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM), blocking ubiquitin binding and disrupting both mono-ubiquitin signaling and overall protein ubiquitination. TAK-243 exhibits antitumor activity and promotes apoptosis. Target: Apoptosis, E1/E2/E3 Enzyme,...
| Keywords: | MLN7243 |
| Application: | Ubiquitin-like modifier-activating enzyme 1 (UBA1) inhibitor |
| CAS | 1450833-55-2 |
| MW: | 519.52 D |
From 41.00€
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Anti-UBA1
Item number: CSB-PA00149A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: UBA1. Antigen Species: Human
| Keywords: | Anti-UBA1, Anti-A1S9T, Anti-Protein A1S9, Anti-Ubiquitin-activating enzyme E1, Anti-Ubiquitin-like modifier-activating... |
| Application: | ELISA, WB, IF |
| Host: | Rabbit |
| Species reactivity: | human |
From 163.00€
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Anti-UBA1
Item number: CSB-PA005917.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-UBA1, Anti-A1S9T, Anti-Protein A1S9, Anti-Ubiquitin-activating enzyme E1, Anti-Ubiquitin-like modifier-activating... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
106.00€
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Anti-UBA1
Item number: CSB-PA098218.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: UBA1. Antigen Species: Human
| Keywords: | Anti-UBA1, Anti-A1S9T, Anti-Protein A1S9, Anti-Ubiquitin-activating enzyme E1, Anti-Ubiquitin-like modifier-activating... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 163.00€
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Anti-UBA1
Item number: CSB-PA186952.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: UBA1. Antigen Species: Human
| Keywords: | Anti-UBA1, Anti-A1S9T, Anti-Protein A1S9, Anti-Ubiquitin-activating enzyme E1, Anti-Ubiquitin-like modifier-activating... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 163.00€
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Anti-UBA1
Item number: CSB-PA339675.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: UBA1. Antigen Species: Human
| Keywords: | Anti-UBA1, Anti-A1S9T, Anti-Protein A1S9, Anti-Ubiquitin-activating enzyme E1, Anti-Ubiquitin-like modifier-activating... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 163.00€
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Anti-UBA1
Item number: CSB-PA551947.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: UBA1. Antigen Species: Human
| Keywords: | Anti-UBA1, Anti-A1S9T, Anti-Protein A1S9, Anti-Ubiquitin-activating enzyme E1, Anti-Ubiquitin-like modifier-activating... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 163.00€
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MLN7243
Item number: Cay30108-1
MLN7243 is an inhibitor of ubiquitin-activating enzyme (UAE, IC50 = 1 nM). It is selective for UAE over NEDD8-activating enzyme (NAE), SUMO-activating enzyme (SAE), and the autophagy-activating enzyme ATG7 (IC50s = 28, 850, and >10,000 nM, respectively). MLN7243 inhibits proliferation in a panel of 30 cancer cell...
| Keywords: | TAK-243, sulfamic acid,... |
| Application: | Ubiquitin-like modifier-activating enzyme 1 (UBA1) inhibitor |
| CAS | 1450833-55-2 |
| MW: | 519.5 D |
From 84.00€
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![Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)](https://www.biomol.com/media/image/16/4d/73/SBB-CE0011-C050_200x200.jpg "Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)")
Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.)...
Item number: SBB-CE0011-C050
UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate...
| Keywords: | Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2 |
| Application: | Assays |
| Expressed in: | Insect cells |
| Origin: | human |
| MW: | 118 kD |
396.00€
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