140 products were found matching "K03176"!
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Entrectinib
Item number: TGM-T3678-100mg
Description: Entrectinib (RXDX-101) is a Trk, ROS1, and ALK inhibitor that inhibits TrkA, TrkB, TrkC, ROS1, and ALK (IC50=1/3/5/12/7 nM) with oral activity and blood-brain-barrier penetration. Entrectinib exhibits both antitumor and CNS activity. Target: ALK, ROS Kinase, ROS, Autophagy, Trk receptor. Smiles:...
| Keywords: | RXDX-101, NMS-E628 |
| Application: | Targets neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1] (NTRK1, TRKA) |
| CAS | 1108743-60-7 |
| MW: | 560.64 D |
From 37.00€
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Repotrectinib
Item number: TGM-T4071-100mg
Description: Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 values of 1.01 nM for WT ALK, 5.3 nM for SRC, 1.08 nM for ALK L1196M, and 1.26 nM for ALK G1202R. Target: ALK, ROS, ROS Kinase, Src, Trk receptor. Smiles: C[C@H]1CNC(=O)c2cnn3ccc(N[C@H](C)c4cc(F)ccc4O1)nc23. References: Dayong...
| Keywords: | TPX-0005, TPX0005, TPX 0005 |
| Application: | Targets proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1] (ROS1) |
| CAS | 1802220-02-5 |
| MW: | 355.37 D |
From 45.00€
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Belizatinib
Item number: TGM-T4257-100mg
Description: Belizatinib (TSR-011) is an effective, oral and dual inhibitor of ALK (IC50: 0.7 nM, wild-type recombinant ALK) and TRKA, TRKB, and TRKC. Target: Trk receptor, ALK. Smiles: CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2ccc(F)cc2)nc2ccc(CN3CCC(CC3)C(C)(C)O)cc12. References: Sullivan I, et al. ALK inhibitors...
| Keywords: | TSR-011 |
| Application: | ALK inhibitor, TrkA/TrkB/TrkC inhibitor |
| CAS | 1357920-84-3 |
| MW: | 577.73 D |
From 37.00€
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TrkA Protein, Human, Recombinant (His & hFc)
Item number: TGM-TMPY-01083-100ug
Description: TrkA Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 66 kDa and the accession number is P04629-1.
| Keywords: | TRKA, p140-TrkA, TRK, TRK1, Trk-A, MTC, neurotrophic tyrosine kinase, receptor, type 1 |
| MW: | 66 kD |
599.00€
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TrkA Protein, Human, Recombinant (His)
Item number: TGM-TMPY-01084-100ug
Description: TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04629-1.
| Keywords: | TRKA, TRK, TRK1, Trk-A, MTC, neurotrophic tyrosine kinase, receptor, type 1, p140-TrkA |
| MW: | 39.5 kD |
From 292.00€
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TrkA Protein, Human, Recombinant (aa 33-417, His)
Item number: TGM-TMPK-00774-100ug
Description: TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects.
| Keywords: | MTC, NTRK1, TRKA, Trk-A, TrkA I, TrkA-I, TRK, TrkAI |
| MW: | 43.00 kD |
From 417.00€
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TrkA Protein, Human, Recombinant (aa 285-413, His)
Item number: TGM-TMPY-01759-100ug
Description: TrkA Protein, Human, Recombinant (aa 285-413, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.1 kDa and the accession number is P04629-1.
| Keywords: | TRK, p140-TrkA, neurotrophic tyrosine kinase, receptor, type 1, Trk-A, TRKA, MTC, TRK1 |
| MW: | 15.1 kD |
From 599.00€
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TrkA Protein, Human, Recombinant (aa 194-413, His)
Item number: TGM-TMPY-01760-100ug
Description: TrkA Protein, Human, Recombinant (aa 194-413, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P04629-1.
| Keywords: | neurotrophic tyrosine kinase, receptor, type 1, MTC, p140-TrkA, Trk-A, TRKA, TRK1, TRK |
| MW: | 26 kD |
599.00€
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TrkA Protein, Mouse, Recombinant (hFc)
Item number: TGM-TMPY-03470-100ug
Description: TrkA Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q3UFB7.
| Keywords: | TrkA, C80751, Tkr, neurotrophic tyrosine kinase, receptor, type 1, trk |
| MW: | 69.2 kD |
599.00€
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TrkA Protein, Mouse, Recombinant (His)
Item number: TGM-TMPY-03536-100ug
Description: TrkA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is Q3UFB7.
| Keywords: | TrkA, neurotrophic tyrosine kinase, receptor, type 1, trk, C80751, Tkr |
| MW: | 43.7 kD |
From 599.00€
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TrkA Protein, Rat, Recombinant (hFc)
Item number: TGM-TMPY-03560-100ug
Description: TrkA Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.2 kDa and the accession number is P35739.
| Keywords: | neurotrophic tyrosine kinase, receptor, type 1 |
| MW: | 69.2 kD |
599.00€
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TrkA Protein, Rat, Recombinant (His)
Item number: TGM-TMPY-04285-100ug
Description: TrkA Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is A6J617.
| Keywords: | neurotrophic tyrosine kinase, receptor, type 1 |
| MW: | 43.7 kD |
From 599.00€
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