36 products were found matching "K02732"!
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Bortezomib
Item number: Cay10008822-1
Bortezomib is a dipeptide boronic acid derivative that reversibly inhibits the 20S proteasome (Ki = 0.6 nM). It binds the beta5-subunit of the 20S proteasome and selectively inhibits chymotryptic activity. In part by blocking the degradation of tumor-suppressing and proapoptotic proteins, bortezomib drives cell...
| Keywords: | LDP-341, MG-341, MLN341, NSC 681239, PS-341,... |
| Application: | Proteasome subunit beta type-1/5 inhibitor |
| CAS | 179324-69-7 |
| MW: | 384.2 D |
From 44.00€
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Delanzomib
Item number: TGM-T6027-100mg
Description: Delanzomib (CEP-18770) is an orally active inhibitor of the chymotrypsin-like activity of proteasome (IC50: 3.8 nM). It only marginally inhibits the tryptic and peptidylglutamyl activities of the proteosome. Target: Apoptosis, Proteasome, NF-kappaB. Smiles:...
| Keywords: | CEP-18770 |
| Application: | Targets 20S proteasome subunit beta 6 [EC:3.4.25.1] (PSMB1) |
| CAS | 847499-27-8 |
| MW: | 413.28 D |
From 40.00€
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Marizomib
Item number: TGM-T16012-1mg
Description: Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (beta5), CT-T-laspase-like (C-L, beta1), and trypsin-like (T-L, beta2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectively. Target: Proteasome. Smiles:...
| Keywords: | ML858, Salinosporamide A, NPI-0052 |
| Application: | Targets 20S proteasome subunit beta 6 [EC:3.4.25.1] (PSMB1) |
| CAS | 437742-34-2 |
| MW: | 313.78 D |
From 552.00€
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Proteasome subunit beta type-1 (PSMB1), human, recombinant
Item number: CSB-RP013954h.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-241aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal GST-tagged. Target Protein Sequence: RFSPYVFNGG TILAIAGEDF AIVASDTRLS EGFSIHTRDS PKCYKLTDKT VIGCSGFHGD CLTLTKIIEA RLKMYKHSNN KAMTTGAIAA MLSTILYSRR FFPYYVYNII GGLDEEGKGA...
| Keywords: | PSC5, PSMB1, Macropain subunit C5, Proteasome gamma chain, Proteasome component C5, Proteasome subunit beta type-1,... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 50.5 kD |
From 219.00€
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Anti-PSMB1
Item number: CSB-PA01395A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: PSMB1. Antigen Species: Human
| Keywords: | Anti-PSC5, Anti-PSMB1, Anti-Macropain subunit C5, Anti-Proteasome gamma chain, Anti-Proteasome component C5,... |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 167.00€
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Bortezomib
Item number: LKT-B5871.5
Proteasome inhibitor.
| Keywords: | Velcade, PS-341, [(1R)-3-Methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl] amino]butyl]boronic acid |
| Application: | Proteasome subunit beta type-1 inhibitor, proteasome subunit beta type-5 inhibitor |
| CAS | 179324-69-7 |
| MW: | 384.24 D |
From 156.00€
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![Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]](https://www.biomol.com/media/image/0e/8d/00/SBB-PS0006-M002_200x200.png "Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]")
Z-Leu-Leu-Glu-AMC [Z-LLE-AMC]
Item number: SBB-PS0006-M002
Lyophilized powder. Soluble in DMSO. Z-LLE-AMC is a fluorogenic peptide substrate for measuring caspase-like activity of the proteasome. Hydrolysis of this substrate by the beta1-subunit of the 20S proteasome is monitored by observing fluorescence at an Excitation wavelength of 345nm and Emission at 445nm. This...
| Keywords: | Proteasome Substrate II |
| Application: | Fluorogenic peptide substrate |
| MW: | 664,8 D |
237.00€
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Anti-PSMB1
Item number: ARG56253.100
Protein function: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome...
| Keywords: | Anti-PSC5, Anti-PSMB1, Anti-Macropain subunit C5, Anti-Proteasome gamma chain, Anti-Proteasome component C5,... |
| Application: | WB, ICC, IF |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
658.00€
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![Delanzomib [CEP-18770]](https://www.biomol.com/media/image/dd/19/42/AG-CR1-3673-M001_200x200.png "Delanzomib [CEP-18770]")
Delanzomib [CEP-18770]
Item number: AG-CR1-3673-M025
Synthetic. Chemical. CAS: 847499-27-8. Formula: C21H28BN3O5. MW: 413.3. Synthetic. Potent, selective, reversible orally bioavailable proteasome inhibitor. Synthetic P2 threonine boronic acid. Targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50=3.8nM). Cross-reacts and inhibits the...
| Keywords: | NPH 007098, CT 47098, CIP 18770,... |
| Application: | Proteasome inhibitor |
| CAS | 847499-27-8 |
| MW: | 413,3 D |
From 33.00€
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![VR23 [Proteasome Inhibitor]](https://www.biomol.com/media/image/a3/db/0c/AG-CR1-3676-M001_200x200.png "VR23 [Proteasome Inhibitor]")
VR23 [Proteasome Inhibitor]
Item number: AG-CR1-3676-M025
Synthetic. Chemical. CAS: 1624602-30-7. Formula: C19H16ClN5O6S. MW: 477.9. Synthetic. Potent selective and reversible chloroquine derivative 20S proteasome inhibitor (all proteolytic subunits). Targets the trypsin-like beta2 subunit of the constitutive 20S proteasome (IC50=1nM). Cross-reacts and inhibits the...
| Keywords: | 7-Chloro-4-[4-[(2,4-dinitrophenyl)sulfonyl]-1-piperazinyl]quinoline |
| Application: | Proteasome inhibitor |
| CAS | 1624602-30-7 |
| MW: | 477,9 D |
From 33.00€
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K-7174 (hydrochloride)
Item number: Cay32773-25
K-7174 is a 20S proteasome inhibitor. It inhibits the beta1, beta2, and beta5 catalytic subunits of the 20S proteasome when used at a concentration of 5 µM. K-7174 (10 µM) reduces TNF-alpha- or IL-1beta-induced adherence of U937 monocytes to human umbilical vein endothelial cells (HUVECs) in a co-culture model of...
| Keywords: | hexahydro-1,4-bis[(4E)-5-(3,4,5-trimethoxyphenyl)-4-penten-1-yl]-1H-1,4-diazepine, dihydrochloride |
| Application: | 20S proteasome inhibitor |
| CAS | 191089-60-8 |
| MW: | 641.7 D |
From 133.00€
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Anti-PSMB1
Item number: ATA-HPA029635.100
Protein function: Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the...
| Keywords: | Anti-PSC5, Anti-PSMB1, Anti-Macropain subunit C5, Anti-Proteasome gamma chain, Anti-Proteasome component C5,... |
| Application: | ICC, IHC, WB |
| Host: | Rabbit |
| Species reactivity: | human |
From 239.00€
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