58 products were found matching "K02470"!
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Novobiocin
Item number: TGM-T20510-100mg
Description: Novobiocin is an orally active and potent antibiotic.Novobiocin is a DNA gyrase inhibitor and heat shock protein 90 (Hsp90) antagonist with inhibitory effects on gyrase and Hsp90. Novobiocin has anti-positive activity and can be used to study highly resistant pneumococcal infections. Target: Antibiotic,...
| Keywords: | Cathomycin, Albamycin, U-6391, U6391, U 6391 |
| Application: | DNA gyrase inhibitor screening |
| CAS | 303-81-1 |
| MW: | 612.62 D |
From 31.00€
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Tosufloxacin tosylate
Item number: TGM-T26368-500mg
Description: Tosufloxacin is a fluoroquinolone antibiotic used to treat susceptible infections. Target: Others. Smiles: Cc1ccc(cc1)S(O)(=O)=O.NC1CCN(C1)c1nc2n(cc(C(O)=O)c(=O)c2cc1F)-c1ccc(F)cc1F. References: Kim YD, Kim MK, Wee WR, Choi HJ. Tosufloxacin deposits in compromised corneas. Optom Vis Sci. 2014...
| Keywords: | T3262, T 3262, T-3262, Tosufloxacin |
| Application: | Antibacterial antibiotic |
| CAS | 115964-29-9 |
| MW: | 576.54 D |
210.00€
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Dihydronovobiocin
Item number: TGM-T37721-5mg
Description: Dihydronovobiocin is a coumarin antibiotic and derivative of novobiocin .1It is active against the bacteriaS. aureus,S. haemolyticus,D. pneumoniae,S. typhosa,K. pneumoniae, andP. multocida(MICs = 0.6, 2, 0.6, 10, 10, and 3 µg/ml, respectively).2Dihydronovobiocin inhibits DNA gyrase subunit B with an...
| Application: | Coumarin antibiotic, DNA gyrase subunit B inhibitor |
| CAS | 29826-16-2 |
| MW: | 614.64 D |
1,943.00€
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Type II topoisomerase inhibitor 1
Item number: TGM-T61054-100mg
Description: Type II topoisomerase inhibitor 1 is a potent and selective inhibitor of E. coli DNA gyrase with an IC50 value of 1.7 nM and forms hydrogen bonds with the Asp73 residue. It inhibits topoisomerase IV activity with an IC50 value of 0.98 µM and is applicable in the antibacterial area [1] [2]. Target:...
| Application: | Type II topoisomerase inhibitor |
| CAS | 2245691-60-3 |
| MW: | 337.33 D |
From 1,491.00€
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GyrB Protein, Salmonella typhi, Recombinant (His & Myc)
Item number: TGM-TMPH-03470-100ug
Description: GyrB Protein, Salmonella typhi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 51.8 kDa and the accession number is P0A2I4.
| Keywords: | gyrB, DNA gyrase subunit B |
| MW: | 51.8 kD |
From 352.00€
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Norfloxacin-d5
Item number: TGM-TMIH-0398-1mg
Description: Norfloxacin-d5 is a deuterated compound of Norfloxacin. Smiles: [2H]C([2H])([2H])C([2H])([2H])N1C=C(C(O)=O)C(=O)C2=CC(F)=C(C=C12)N1CCNCC1
| Application: | GC-MS, LC-MS, internal standard, quantification, antibacterial, topoisomerase IV inhibitor |
| CAS | 1015856-57-1 |
| MW: | 324.36 D |
Please request pricing for this article.
Sarafloxacin-d8 Hydrochloride
Item number: TGM-TMIJ-0037-1mg
Description: Sarafloxacin-d8 Hydrochloride is a deuterated compound of Sarafloxacin Hydrochloride. Sarafloxacin Hydrochloride has a CAS number of 91296-87-6. Sarafloxacin hydrochloride, a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin. Smiles:...
| Application: | GC-MS, LC-MS internal standard, quantification, antibacterial nucleic acid biosynthesis inhibitor |
| CAS | 2733145-07-6 |
| MW: | 429.87 D |
Please request pricing for this article.
(R)-Ofloxacin
Item number: TGM-T17307-10mg
Description: (R)-Ofloxacin is a R-isomer of Ofloxacin, an antibiotic used to treat a number of bacterial infections. Target: Others. Smiles: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OC[C@@H](C)N3C=C1C(O)=O. References: Lahouidak S, Soriano ML, Salghi R, Zougagh M, Ríos Á. Graphene quantum dots for enhancement of...
| Keywords: | (R)-(+)-Ofloxacin, (+)-Ofloxacin, DR 3354, DR3354, D-Ofloxacin, DR-3354 |
| Application: | Fluoroquinolone antibiotic, DNA gyrase inhibitor |
| CAS | 100986-86-5 |
| MW: | 361.37 D |
From 166.00€
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DNA gyrase subunit B (gyrB), partial, Salmonella typhi,...
Item number: CSB-EP358232SWW.1
Organism: Salmonella typhi. Source: E.coli. Expression Region: 415-804aa. Protein Length: partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: PALSELYLVE GDSAGGSAKQ GRNRKNQAIL PLKGKILNVE KARFDKMLSS QEVATLITAL GCGIGRDEYN PDKLRYHSII IMTDADVDGS HIRTLLLTFF YRQMPEIVER GHVYIAQPPL...
| Keywords: | STY3943, DNA gyrase subunit B, Recombinant Salmonella typhi DNA gyrase subunit B (gyrB), partial |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | Salmonella typhi |
| MW: | 51.8 kD |
From 354.00€
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Ciprofloxacin (hydrochloride hydrate)
Item number: Cay14286-5
Ciprofloxacin is a fluoroquinolone antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria in vitro, including S. aureus, L. monocytogenes, P. aeruginosa, Legionella, N. gonorrhoeae, and H. pylori (MIC50s = 0.004-1 µg/ml). It is also active against clinical isolates of Bacteroides,...
| Keywords: | BAY-o 9867, NSC 620634, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid,... |
| Application: | Antibiotic |
| CAS | 86393-32-0 |
| MW: | 367.8 D |
From 43.00€
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Novobiocin (sodium salt)
Item number: Cay18457-1
Bacterial DNA gyrase is a heterodimeric type II topoisomerase that negatively supercoils circular double-stranded DNA. Novobiocin is a coumarin antibiotic, first isolated from Streptomyces species, that inhibits the ATPase activity of DNA gyrase. Its antibacterial activity arises from competitive inhibition of the...
| Keywords: | NSC 2382,... |
| Application: | Bacterial DNA gyrase (GyrB) inhibitor |
| CAS | 1476-53-5 |
| MW: | 634.6 D |
From 60.00€
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Levofloxacin (hydrate)
Item number: Cay20382-1
Levofloxacin is a fluoroquinolone antibiotic and the active stereoisomer of ofloxacin (Cay-22891). It is active against S. aureus, S. epidermidis, B. subtilis, E. coli, P. aeruginosa, and K. pneumoniae (MICs = 0.25, 0.25, 0.5, 0.03, 4, and 0.25 µg/ml, respectively). Levofloxacin inhibits S. aureus DNA gyrase and...
| Keywords: | MP-376,... |
| Application: | Antibacterial, nucleic acid biosynthesis inhibitor |
| CAS | 138199-71-0 |
| MW: | 361.4 D |
From 39.00€
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