74 products were found matching "K02202"!
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THZ1-R
Item number: TGM-T13153-100mg
Description: THZ1-R displays diminished activity for CDK7 inhibition(Kd:142 nM). Target: CDK. Smiles: CN(C)CCCC(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1. References: Kwiatkowski N, et al. Targeting transcription regulation in cancer with a covalent CDK7 inhibitor. Nature. 2014 Jul...
| Application: | Non-cysteine reactive THZ1 derivative, Cdk7 inhibitor |
| CAS | 1621523-07-6 |
| MW: | 568.07 D |
From 380.00€
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THZ1
Item number: TGM-T3664-100mg
Description: THZ1 (CDK7 inhibitor) is a novel selective and potent covalent CDK7 inhibitor. Target: CDK. Smiles: CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1. References: Kwiatkowski N, et al. Nature. 2014, 511(7511):616-20.
| Keywords: | THZ1 2HCl, CDK7 inhibitor |
| Application: | CDK7 inhibitor |
| CAS | 1604810-83-4 |
| MW: | 566.05 D |
From 81.00€
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LDC4297
Item number: TGM-T4051-1mg
Description: LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor. Target: CDK, HSV. Smiles: CC(C)c1cnn2c(NCc3ccccc3-n3cccn3)nc(OC3CCCNC3)nc12. References: Hutterer C, et al. A novel CDK7 inhibitor of the Pyrazolotriazine class exerts broad-spectrum antiviral activity at nanomolar concentrations. Antimicrob...
| Keywords: | LDC044297 |
| Application: | CDK7 inhibitor |
| CAS | 1453834-21-3 |
| MW: | 432.52 D |
49.00€
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THZ2
Item number: TGM-T7296-100mg
Description: THZ2 (CDK7-IN-1), an analog of THZ1, is a potent and selective CDK7 inhibitor(IC50:13.9 nM),with the potential to treat Triple-negative breast cancer (TNBC). Target: CDK. Smiles: CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1cccc(Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c1. References: Huang JR, Qin WM, Wang K,et...
| Keywords: | CDK7-IN-1 |
| Application: | Cdk7 inhibitor |
| CAS | 1604810-84-5 |
| MW: | 566.05 D |
From 77.00€
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CDK7 Protein, Human, Recombinant (His)
Item number: TGM-TMPH-01172-100ug
Description: CDK7 Protein, Human, Recombinant (His) is expressed in Baculovirus.
| Keywords: | Cyclin-dependent kinase 7, 39 kDa protein kinase, CDK-activating kinase 1, TFIIH basal transcription factor complex kinase... |
| MW: | 41.5 kD |
From 369.00€
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CDK7 Protein, Human, Recombinant
Item number: TGM-TMPH-01173-100ug
Description: CDK7 Protein, Human, Recombinant is expressed in E. coli.
| Keywords: | CDKN7, MO15, CAK1, CDK-activating kinase 1, CDK7, 39 kDa protein kinase, TFIIH basal transcription factor complex kinase... |
| MW: | 39.2 kD |
From 390.00€
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BS-181 hydrochloride
Item number: TGM-T6162-100mg
Description: BS-181 hydrochloride (BS-181 HCl) is a highly selective CDK7 inhibitor with IC50 of 21 nM. It is more than 40-fold selective for CDK7 than CDK1, 2, 4, 5, 6, or 9. Target: CDK. Smiles: Cl.CC(C)c1cnn2c(NCc3ccccc3)cc(NCCCCCCN)nc12. References: Ali S, et al. Cancer Res, 2009, 69(15), 6208-6215.
| Keywords: | BS-181 HCl |
| Application: | CDK7 inhibitor |
| CAS | 1397219-81-6 |
| MW: | 416.99 D |
From 31.00€
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Cyclin-dependent kinase 7 (CDK7), human, recombinant
Item number: CSB-BP005075HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-346aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MALDVKSRAK RYEKLDFLGE GQFATVYKAR DKNTNQIVAI KKIKLGHRSE AKDGINRTAL REIKLLQELS HPNIIGLLDA FGHKSNISLV FDFMETDLEV IIKDNSLVLT PSHIKAYMLM TLQGLEYLHQ...
| Keywords: | CAK, CDK7, p39 Mo15, EC=2.7.11.23, EC=2.7.11.22, 39 kDa protein kinase, CDK-activating kinase 1, Cyclin-dependent kinase... |
| Application: | Activity not tested |
| Expressed in: | Insect cells |
| Origin: | human |
| MW: | 41.5 kD |
From 375.00€
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Cyclin-dependent kinase 7 (CDK7), human, recombinant
Item number: CSB-EP005075HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-346aa. Protein Length: Full Length. Tag Info: Tag-Free. Target Protein Sequence: MALDVKSRAK RYEKLDFLGE GQFATVYKAR DKNTNQIVAI KKIKLGHRSE AKDGINRTAL REIKLLQELS HPNIIGLLDA FGHKSNISLV FDFMETDLEV IIKDNSLVLT PSHIKAYMLM TLQGLEYLHQ HWILHRDLKP NNLLLDENGV...
| Keywords: | CAK, CDK7, p39 Mo15, EC=2.7.11.23, EC=2.7.11.22, 39 kDa protein kinase, CDK-activating kinase 1, Cyclin-dependent kinase... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | 39.2 kD |
From 395.00€
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Anti-CDK7
Item number: CSB-PA001537.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-CAK, Anti-CDK7, Anti-p39 Mo15, EC=2.7.11.22, EC=2.7.11.23, Anti-39 kDa protein kinase, Anti-CDK-activating kinase 1,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
From 126.00€
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Anti-CDK7
Item number: CSB-PA010190.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Keywords: | Anti-CAK, Anti-CDK7, Anti-p39 Mo15, EC=2.7.11.22, EC=2.7.11.23, Anti-39 kDa protein kinase, Anti-CDK-activating kinase 1,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
283.00€
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Anti-CDK7
Item number: CSB-PA440881.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CDK7. Antigen Species: Human
| Keywords: | Anti-CAK, Anti-CDK7, Anti-p39 Mo15, EC=2.7.11.22, EC=2.7.11.23, Anti-39 kDa protein kinase, Anti-CDK-activating kinase 1,... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
From 167.00€
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