70 products were found matching "K01488"!

Description: Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation and function of T and B lymphocytes. Adenosine deaminase is a polymorphic enzyme that...

Organism: Escherichia coli (strain K12). Source: E.coli. Expression Region: 1-333aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MIDTTLPLTD IHRHLDGNIR PQTILELGRQ YNISLPAQSL ETLIPHVQVI ANEPDLVSFL TKLDWGVKVL ASLDACRRVA FENIEDAARH GLHYVELRFS PGYMAMAHQL PVAGVVEAVI...

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ADA. Antigen Species: Human

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ADA. Antigen Species: Human

EHNA is a reversible adenosine deaminase inhibitor (IC50 = 1.2 µM in human red blood cells) that also selectively inhibits the cGMP-specific phosphodiesterase (PDE2) (IC50s = 0.8 and 2 µM from human and porcine myocardium, respectively, 3.5 µM in rat hepatocyte, and 5.5 µM in human platelet). Comparatively, EHNA is...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Chicken ADA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Chicken ADA. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ADA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ADA. Next,...

Pentostatin is a purine antimetabolite and an adenosine deaminase (ADA) inhibitor (Ki = 0.09 nM). It reduces 2'-deoxyadenosine-induced growth inhibition of MOLT-4 lymphoblast cells (Ki = 5.6 µM). It inhibits erythrocyte and ascites tumor cell ADA in an L1210 murine skin lymphocytic leukemia model when administered...

Isolated from Streptomyces sp. Soluble in DMSO or methanol. Nucleoside analog. Cytotoxic. DNA, RNA and protein synthesis inhibitor. Shows anticancer activity. Anti-mycobacterial. Has tuberculostatic activity. Antifungal activity. Antiviral (anti-Herpes). Adenosine deaminase inhibitor. Can be used to analyze...

Protein function: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell...

Protein function: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine (PubMed:8452534, PubMed:16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a...

Protein function: Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine (PubMed:8452534, PubMed:16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a...