151 products were found matching "K01370"!

Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...

Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic Caspase-1 is the best-described inflammatory caspase. It...

Kit includes 660-YVAD-FMK red caspase-1 probe, 10x Apoptosis Wash Buffer, Fixative, Technical Protocol. The red FLICA® 660-YVAD-FMK caspase-1 detection probe is comprised of the preferred affinity peptide sequence for active caspase-1 (YVAD), a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK)...

This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.

Description: Z-Asp-CH2-DCB is an irreversible inhibitor of broad-spectrum caspases. Target: Others. Smiles: OC(=O)C[C@H](NC(=O)OCc1ccccc1)C(=O)COC(=O)c1c(Cl)cccc1Cl. References: Krakauer T, et al. Caspase inhibitors attenuate superantigen-induced inflammatory cytokines, chemokines, and T-cell proliferation. Clin...

Description: Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1beta , and IFN-gamma. Pralnacasan is an effective, non-peptide, and orally active interleukin-1beta converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential for osteoarthritis and rheumatoid arthritis treatment. Target: Others....

Description: Imperatorin (8-Isopentenyloxypsoralene) is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo. Target: TRP/TRPV Channel, NOD, AChR, AChE. Smiles: CC(C)=CCOc1c2occc2cc2ccc(=O)oc12. References: Koziol, E., &...

Description: Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1beta and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity. Target: Immunology/Inflammation related, Pyroptosis, Caspase, IL Receptor. Smiles:...

Description: Dabcyl YVADAPV EDANS is a fluorescent IL-1beta converting enzyme (ICE) substrate that can be used to detect ICE-like protease activity. Dabcyl YVADAPV EDANS detects fluorescence at lambdaex=360 nm, lambdaem=480 nm. Smiles:...

Description: Ac-YVAD-AFC is a fluorometric peptide substrate of caspase-1, featuring an excitation wavelength (lambda excitation) of 400 nm and an emission wavelength (lambda emission) of 505 nm [1] [2]. Smiles:...

Description: Caspase-1 Protein, Human, Recombinant (HA) is expressed in E. coli expression system with C-HA tag. The predicted molecular weight is 11.4 kDa and the accession number is P29466.