65 products were found matching "K01348"!

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 21-431aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: SNELHQVPSN CDCLNGGTCV SNKYFSNIHW CNCPKKFGGQ HCEIDKSKTC YEGNGHFYRG KASTDTMGRP CLPWNSATVL QQTYHAHRSD ALQLGLGKHN YCRNPDNRRR PWCYVQVGLK...

ZK 824859 is an inhibitor of urokinase-type plasminogen activator (uPA, IC50s = 79 and 410 nM for the human and mouse proteins, respectively). It is selective for human uPA over human tissue-type plasminogen activator (tPA) and plasmin (IC50s = 1,580 and 1,330 nM, respectively) but not selective for mouse uPA over...

UK 122 is an inhibitor of urokinase-type plasminogen activator (uPA, IC50 = 0.2 µM). It is selective for uPA over tissue-type plasminogen activator (tPA), trypsin, plasmin, and thrombin (IC50s = >100 µM for all). UK 122 (100 µM) inhibits the migration and invasion of CFPAC-1 pancreatic cancer cells. It prevents...

BC-11 is an inhibitor of the serine protease urokinase-type plasminogen activator (uPA). It reduces cell viability of MDA-MB-231 cells (EC50 = 117 µM).Formal Name: carbamimidothioic acid, (4-boronophenyl)methyl ester, monohydrobromide. CAS Number: 443776-49-6. Synonyms: uPA Inhibitor BC-11, Urokinase-type...

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen...

6-Aminocaproic acid is an inhibitor of the plasmin activating enzymes streptokinase, fibrinokinase, and urokinase (IC50s = ~8 µM for all in an enzyme assay). It is selective for plasmin activating enzymes over trypsin (IC50 = >500 µM). 6-Aminocaproic acid inhibits in vitro plasmin activation and fibrinolysis in a...

Gabexate is a competitive inhibitor of serine proteases that inhibits human thrombin, urokinase, plasmin, and Factor Xa (Kis = 0.97, 1.3, 1.6, and 8.5 µM, respectively)., It also inhibits bovine thrombin, Factor Xa, and trypsin, and porcine plasma kallikrein (Kis = 1.4, 2.1, 2.6, and 0.2 µM, respectively)., In...

Protein function: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. [The UniProt Consortium]

Natural and recombinant human Upa. There is no detectable cross-reactivity with other relevant proteins. Protein function: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. [The UniProt Consortium]

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Plasminogen activator, urokinase Protein function: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. [The UniProt Consortium]