73 products were found matching "K01334"!
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Vemircopan
Item number: TGM-T39493-10mg
Description: Vemircopan is a complement factor D inhibitor. Target: Others. Smiles: [H][C@@]12C[C@]1(C)C[C@H](N2C(=O)Cn1nc(C(C)=O)c2cc(ccc12)-c1cnc(C)nc1)C(=O)Nc1nc(Br)ccc1C. References: Wiles, Jason Allan, Phadke, Avinash S., Deshpande, Milind, Agarwak, Atul, Chen, Dawei, Gadhachanda, Venkat Rao, Hashimoto,...
| Keywords: | ALXN2050, ACH-5228, ACH0145228 |
| Application: | Targets complement factor D [EC:3.4.21.46] (CFD) |
| CAS | 2086178-00-7 |
| MW: | 602.493 D |
From 870.00€
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Danicopan
Item number: TGM-T8509-100mg
Description: Danicopan (ACH-4471) (ACH-4471) is a selective, orally active small molecule factor D inhibitor with high binding affinity to human factor D, with a Kd value of 0.54 nM. Danicopan (ACH-4471) inhibits the activity of the complement replacement pathway (APC) and may block the complement replacement...
| Keywords: | ACH-4471 |
| Application: | Targets complement factor D [EC:3.4.21.46] (CFD) |
| CAS | 1903768-17-1 |
| MW: | 580.41 D |
From 97.00€
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Complement Factor D/CFD Protein, Human, Recombinant (hFc)
Item number: TGM-TMPK-00755-100ug
Description: Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal...
| Keywords: | C3 convertase activator, AMBP-1, EC 3.4.21, DF, EC 3.4.21.46, Complement factor D, PFD, FACTOR D, CFD, ADN, Adipsin |
| MW: | 51.2 kD |
From 485.00€
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Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
Item number: TGM-TMPK-00151-100ug
Description: Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal...
| Keywords: | AMBP-1, C3 convertase activator, FACTOR D, PFD, Complement factor D, DF, Adipsin, EC 3.4.21, CFD, ADN, EC 3.4.21.46 |
| MW: | 52.2 kD |
From 533.00€
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Complement Factor D/CFD Protein, Rhesus macaque,...
Item number: TGM-TMPK-00671-100ug
Description: Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal...
| Keywords: | Adipsin, CFD, Complement factor D, ADN, DF, AMBP-1, EC 3.4.21, PFD, C3 convertase activator, EC 3.4.21.46, FACTOR D |
| MW: | 25.7 kD |
From 485.00€
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Complement factor D Protein, Rat, Recombinant (His & Myc)
Item number: TGM-TMPH-03271-100ug
Description: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D Protein, Rat, Recombinant (His & Myc) is expressed...
| Keywords: | Df, Complement factor D, Properdin factor D, Endogenous vascular elastase, Adn, C3 convertase activator, Adipsin, Cfd |
| MW: | 29.8 kD |
From 464.00€
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Complement factor D Protein, Rat, Recombinant (His)
Item number: TGM-TMPH-03272-100ug
Description: Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
| Keywords: | C3 convertase activator, Complement factor D, Endogenous vascular elastase, Adn, Df, Adipsin, Properdin factor D, Cfd |
| MW: | 27.8 kD |
From 281.00€
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Complement Factor D/CFD Protein, Mouse, Recombinant (His)
Item number: TGM-TMPJ-00149-10ug
Description: Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for...
| Keywords: | Cfd, 28 kDa adipocyte protein, Adipsin, Complement factor D, Adn, Properdin factor D, Df, C3 convertase activator |
| MW: | 49 kD |
From 181.00€
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Complement Factor D/CFD Protein, Mouse, Recombinant...
Item number: TGM-TMPY-02167-500ug
Description: Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P03953-2.
| Keywords: | Adn, DF, complement factor D (adipsin) |
| MW: | 27.4 kD |
From 497.00€
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Complement Factor D/CFD Protein, Human, Recombinant (His)
Item number: TGM-TMPY-02183-500ug
Description: Complement Factor D/CFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P00746.
| Keywords: | ADIPSIN, FACTOR D, ADN, DF, PFD, complement factor D (adipsin) |
| MW: | 25.8 kD |
From 497.00€
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Complement factor D (Cfd), rat, recombinant
Item number: CSB-EP005271RA.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 26-263aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: ILGGQEAMAH ARPYMASVQV NGTHVCGGTL VDEQWVLSAA HCMDGVTKDE VVQVLLGAHS LSSPEPYKHL YDVQSVVLHP GSRPDSVEDD...
| Keywords: | Cfd, Adn, Adipsin, EC=3.4.21.46, Properdin factor D, Complement factor D, C3 convertase activator, Endogenous vascular... |
| Application: | Activity not tested |
| Expressed in: | E.coli |
| Origin: | rat |
| MW: | 30.8 kD |
From 292.00€
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Complement factor D (Cfd), rat, recombinant
Item number: CSB-YP005271RA.1
Organism: Rattus norvegicus (Rat). Source: Yeast. Expression Region: 26-263aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: ILGGQEAMAH ARPYMASVQV NGTHVCGGTL VDEQWVLSAA HCMDGVTKDE VVQVLLGAHS LSSPEPYKHL YDVQSVVLHP GSRPDSVEDD LMLFKLSHNA SLGPHVRPLP LQREDREVKP...
| Keywords: | Cfd, Adn, Adipsin, EC=3.4.21.46, Properdin factor D, Complement factor D, C3 convertase activator, Endogenous vascular... |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | rat |
| MW: | 27.8 kD |
From 347.00€
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