47 products were found matching "K01324"!
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PKSI-527
Item number: TGM-T35579-2mg
Description: PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 µM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 µM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and...
| Application: | Plasma kallikrein inhibitor |
| CAS | 128837-71-8 |
| MW: | 473.99 D |
77.00€
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Berotralstat
Item number: TGM-T35869-100mg
Description: Berotralstat (BCX7353) is a second-generation, synthetic, and orally active plasma kallikrein inhibitor with low toxicity. It is highly specific and effectively used in the research of hereditary angioedema (HAE) attacks. Berotralstat functions by inhibiting the enzymatic activity of plasma kallikrein,...
| Application: | Targets plasma kallikrein [EC:3.4.21.34] (KLKB1) |
| CAS | 1809010-50-1 |
| MW: | 562.573 D |
From 1,520.00€
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H-D-Pro-Phe-Arg-pNA . 2 HCl
Item number: TGM-T37033-250mg
Description: pFR-pNA, chromogenic substrate for the determination of plasma kallikrein-like activity. CAS Number (net): 64816-19-9. Target: Others. Smiles: NC(NCCC[C@@H](C(Nc1ccc([N+]([O-])=O)cc1)=O)NC([C@@H](NC([C@H]2CCCN2)=O)Cc3ccccc3)=O)=N.Cl.Cl
| Application: | Photometric plasma kallikrein substrate |
| CAS | 62354-56-7 |
| MW: | 611.52 D |
From 198.00€
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Sebetralstat
Item number: TGM-T39350-100mg
Description: Sebetralstat (KVD900) is an inhibitor of plasma kallikrein and can be used in studies about metabolic diseases. Target: Others. Smiles: COCc1nn(Cc2ccc(Cn3ccccc3=O)cc2)cc1C(=O)NCc1nccc(OC)c1F. References: WO2016083820
| Keywords: | KVD900 |
| Application: | Targets plasma kallikrein [EC:3.4.21.34] (KLKB1) |
| CAS | 1933514-13-6 |
| MW: | 491.51 D |
From 31.00€
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Berotralstat HCl
Item number: TGM-T70161-100mg
Description: Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE. Target: Others. Smiles:...
| Application: | Targets plasma kallikrein [EC:3.4.21.34] (KLKB1) |
| CAS | 1809010-52-3 |
| MW: | 635.4886 D |
From 1,971.00€
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KLKB1 Protein, Mouse, Recombinant (His)
Item number: TGM-TMPK-00857-100ug
Description: Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Mouse, Recombinant...
| Keywords: | Plasma kallikrein, KLKB1, PKK, Fletcher factor, KLK3, Kininogenin |
| MW: | 70.3 kD |
From 464.00€
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KLKB1 Protein, Human, Recombinant (His)
Item number: TGM-TMPK-00766-100ug
Description: Plasma kallikrein, also known as Fletcher factor or kallikrein B1 (KLKB1), is a serine endopeptidase, like its homologs tissue kallikrein and kallikrein-related peptidases (KLKs). Its physiological role is to catalyze the release of kinins and other vasoactive peptides. KLKB1 Protein, Human, Recombinant...
| Keywords: | Fletcher factor, Plasma kallikrein, KLKB1, PKK, Kininogenin, KLK3 |
| MW: | 70.3 kD |
From 464.00€
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Feniralstat
Item number: TGM-T63507-100mg
Description: Feniralstat is a pyrazole derivative, a potent inhibitor of kallikrein, which inhibits human plasma kinase (pKal) (IC50: 6.7 nM).Feniralstat does not inhibit human KLK1, human FXIa and human factor Xlla (IC50 >40 µM). Target: Others. Smiles: COCc1nn(Cc2ccc(Cn3cc(F)ccc3=O)cc2)cc1C(=O)NCc1nccc(OC)c1F
| Application: | Targets plasma kallikrein [EC:3.4.21.34] (KLKB1) |
| CAS | 2166320-76-7 |
| MW: | 509.5 D |
From 1,520.00€
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Plasma kallikrein (KLKB1), partial, human, recombinant
Item number: CSB-YP012461HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 20-390aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: GCLTQLYENA FFRGGDVASM YTPNAQYCQM RCTFHPRCLL FSFLPASSIN DMEKRFGCFL KDSVTGTLPK VHRTGAVSGH SLKQCGHQIS ACHRDIYKGV DMRGVNFNVS KVSSVEECQK RCTNNIRCQF FSYATQTFHK...
| Keywords: | KLK3, KLKB1, EC=3.4.21.34, Recombinant Human Plasma kallikrein (KLKB1), partial |
| Application: | Activity not tested |
| Expressed in: | Yeast |
| Origin: | human |
| MW: | 43.4 kD |
From 242.00€
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Human KLK3 Protein, His Tag
Item number: DIM-PME101134.10
Recombinant human KLK3 protein with C-terminal 6×His tag. KLK3(Ala18-Pro261) 6×His tag, Protein function: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also...
| Keywords: | PSA, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, APS |
| Expressed in: | Human cells |
| Origin: | human |
| CAS | 12 |
| MW: | 27.7 kD |
From 172.00€
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Anti-Cleaved-KLKB1 (R390)
Item number: CSB-PA000082.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Keywords: | Anti-KLK3, Anti-KLKB1, EC=3.4.21.34, Fletcher factor antibody, kallikrein B plasma antibody, Kallikrein B plasma (Fletcher... |
| Application: | ELISA, WB, IHC |
| Host: | Rabbit |
| Species reactivity: | human |
From 126.00€
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AEBSF . hydrochloride
Item number: AG-CR1-3610-M050
White solid. Soluble in water or 100% ethanol. Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF, Potent, selective inhibitor of Site-1-protease (S1P), Used to characterize the downstream result of SREBP inhibition...
| Keywords: | 4-(2-Aminoethyl)benzenesulfonylfluoride, Pefabloc SC |
| Application: | Chymotrypsin / kallikrein / plasmin / thrombin / trypsin inhibitor, Stable PMSF alternative |
| CAS | 30827-99-7 |
| MW: | 239,7 D |
From 44.00€
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