210 products were found matching "K01283"!

Spirapril is an inhibitor of angiotensin-converting enzyme (ACE, IC50 = 67 nM) and a prodrug form of spiraprilat. It inhibits the angiotensin I-induced pressor response in rats and dogs with half-maximal inhibitory dose (ID50) values of 16 and 262 µg/kg, respectively. Spirapril (5 mg/kg) decreases systolic blood...

Foroxymithine is a microbial metabolite that has been found in S. nitrosporeus and an angiotensin-converting enzyme (ACE) inhibitor (IC50 = 7 µg/ml for the bovine lung enzyme). It is selective for ACE over nine peptidases (IC50s = >100 µg/ml for all). In vivo, foroxymithine (25 and 50 mg/kg) reduces systolic blood...

Imidaprilat is an inhibitor of angiotensin-converting enzyme (ACE, IC50 = 2.6 nM) and an active metabolite of the prodrug imidapril (Cay-18854). It inhibits bradykinin-induced contractions in isolated guinea pig ileum (IC50 = 1.7 nM). Imidaprilat (50 nM) reduces adhesion induced by chemokine (C-C-) motif ligand 2...

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Cattle ACE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Cattle ACE. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ACE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ACE. Next, Avidin...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rabbit ACE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rabbit ACE. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ACE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ACE. Next,...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ACE. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ACE. Next,...

Colormetric. Detection Range: 78.13-5000 pg/mL. Protein function: Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which...

Captopril is an inhibitor of angiotensin-converting enzyme (ACE, IC50 = 23 nM for the rabbit lung enzyme). It inhibits contractions in isolated guinea pig ileal segments induced by angiotensin I or bradykinin (IC50s = 23 and 3 nM, respectively) but not those induced by angiotensin II, histamine, acetylcholine,...

Ramipril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor ramiprilat (Cay-15557). Ramipril (2.5 mg/kg per day, p.o.) reduces systolic blood pressure in spontaneously hypertensive rats. It reduces aortic valve backscatter and improves aortic flow in a rabbit model of aortic valve stenosis....