253 products were found matching "K01278"!
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DPP (IV) Inhibitor Screening Assay Kit
Item number: Cay700210-96
DPP (IV) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by DPP (IV). GLP-1 extends the action of insulin while suppressing the release...
| Keywords: | Dipeptidyl peptidase IV |
| Application: | DPP (IV) inhibitor screening |
| Species reactivity: | human |
476.00€
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DPP4/CD26 Polyclonal antibody
Item number: E-AN006030L.100
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides, and peptide hormones. The enzyme...
| Keywords: | Anti-ADCP2, DPP4/CD26 Polyclonal antibody |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | mouse,rat |
From 109.00€
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DBPR108
Item number: Cay41117-10
DBPR108 is an inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 0.015 µM). It is selective for DPP-4 over DPP-8 and DPP-9 (IC50s = >50 µM for both). DBPR108 (10 mg/kg) increases plasma levels of glucagon-like peptide 1 (GLP-1) and insulin in rats. It reduces blood glucose levels in an oral glucose tolerance test in...
| Keywords: | Prusogliptin, 1-[2S-[[1,1-dimethyl-3-oxo-3-(1-pyrrolidinyl)propyl]amino]acetyl]-4S-fluoro-2-pyrrolidinecarbonitrile |
| Application: | DPP-4 inhibitor |
| CAS | 1186426-66-3 |
| MW: | 324.4 D |
From 136.00€
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Vildagliptin
Item number: TGM-T1502-10mg
Description: Vildagliptin (LAF237) is a cyanopyrrolidine-based, orally bioavailable inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Vildagliptin's cyano moiety undergoes hydrolysis and this inactive metabolite is excreted mainly via the urine. Target: Ferroptosis, Proteasome, Apoptosis,...
| Keywords: | LAF237, NVP-LAF 237 |
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 274901-16-5 |
| MW: | 303.4 D |
From 31.00€
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Vildagliptin carboxylic acid metabolite (trifluoroacetate...
Item number: TGM-T35815-1mg
Description: Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. Vildagliptin carboxylic acid metabolite has an IC50 value of 477 µM for DPP-4 in human Caco-2 cells. It is formed from hydrolysis of the cyano group on vildagliptin....
| Application: | Major vildagliptin metabolite |
| CAS | 565453-41-0 |
| MW: | 436.428 D |
From 142.00€
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Camegliptin
Item number: TGM-T26941-25mg
Description: Cameglipti, a dipeptidyl peptidase IV (DPP-4) inhibitor, is used potentially for the treatment of type 2 diabetes. Target: Others. Smiles: O(C)C=1C=C2[C@]3(N(C[C@@H]([C@@H](N)C3)N4C[C@@H](CF)CC4=O)CCC2=CC1OC)[H]. References: Kuhlmann O, Carlile D, Noe J, Bentley D. Interaction potential of Carmegliptin...
| Keywords: | R-1579, RG-1579, RO-4876904, RG1579, RO-4876904-001, R1579 |
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 813452-18-5 |
| MW: | 377.45 D |
From 2,421.00€
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Denagliptin tosylate
Item number: TGM-T31378-100mg
Description: Denagliptin (GW823093 or GSK-823093) is a dipeptidyl peptidase IV (DPP-IV) inhibitor. Target: Others. Smiles: S(=O)(=O)(O)C1=CC=C(C)C=C1.C([C@@H](C(=O)N1[C@H](C#N)C[C@H](F)C1)N)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3. References: De Serres M, Bowers G, Boyle G, Beaumont C, Castellino S, Sigafoos J, Dave M,...
| Keywords: | GW823093, GW 823093, GW-823093, GSK823093, GSK-823093, GSK 823093 |
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 811432-66-3 |
| MW: | 545.57 D |
From 1,520.00€
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Gly-Pro-pNA hydrochloride
Item number: TGM-T36583-100mg
Description: Gly-Pro-pNA hydrochloride (Gly-Pro p-nitroanilide hydrochloride) is a dipeptidyl peptidase inhibitor that inhibits dipeptidyl peptidase II, dipeptidyl peptidase IV and dipeptidyl peptidase IX. Target: Proteasome. Smiles: Cl.NCC(=O)N1CCCC1C(=O)Nc1ccc(cc1)[N+]([O-])=O. References: Rai C, et al. Whey...
| Keywords: | Gly-Pro p-nitroanilide hydrochloride |
| Application: | Chromogenic DPP4 substrate |
| CAS | 103213-34-9 |
| MW: | 328.75 D |
From 34.00€
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Teneligliptin
Item number: TGM-T37522-10mg
Description: Teneligliptin (MP-513) is a potent prolylthiazolidine-based DPP-4 inhibitor that competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM. Target: Others. Smiles: Cc1cc(N2CCN(CC2)[C@@H]2CN[C@@H](C2)C(=O)N2CCSC2)n(n1)-c1ccccc1....
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 760937-92-6 |
| MW: | 426.58 D |
From 31.00€
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Teneligliptin hydrobromide hydrate
Item number: TGM-T41250-10mg
Description: Teneligliptin hydrobromide hydrate is a potent, competitive, and long-lasting DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC 50 s of approximately 1 nM [1]. Target: Others. Smiles:...
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 1572583-29-9 |
| MW: | 525.51 D |
From 31.00€
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Saxagliptin hydrochloride
Item number: TGM-T6203L-5mg
Description: Saxagliptin is a new oral hypoglycemic of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in...
| Keywords: | Saxagliptin HCl, BMS-477118, Saxagliptin, BMS477118, BMS 477118 |
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 709031-78-7 |
| MW: | 351.87 D |
970.00€
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Carmegliptin dihydrochloride
Item number: TGM-T68652-100mg
Description: Carmegliptin dihydrochloride is the salt form of Camegliptin (free base), also known as RG-1579 and RO4876904, a dipeptidyl peptidase IV (DPP-4) inhibitor potentially for the treatment of type 2 diabetes. Target: Others. Smiles: Cl.Cl.[H][C@@]12C[C@H](N)[C@H](CN1CCc1cc(OC)c(OC)cc21)N1C[C@@H](CF)CC1=O
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 813452-14-1 |
| MW: | 450.38 D |
From 2,421.00€
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